Clinical trials: sponsored by University of Manitoba
Smoking Cessation
Manitoba Pharmacist Initiated Smoking Cessation Pilot Project
A single arm pilot study conducted to assess the feasibility of having Manitoba Pharmacists provide support (product and cognitive) to low-income (receiving social assistance) smokers wishing to quit smoking.
- Trial name
- NCT02554071
- Testing
- Pharmacist - Smoking Cessation Support
- Where
- Canada
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Chronic Pain
Online Chronic Pain Therapy for Adults
This study will evaluate the usefulness of an online, self-directed treatment for chronic pain that has been designed specifically for individuals who are currently or have previously served in the military.
- Trial name
- NCT01600248
- Testing
- Online ABBT for Chronic Pain in Military
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of Manitoba
ACL-injury
The Effectiveness of Neuromuscular Training in Healthy and ACL-Injured Adolescent Females
Recently, there has been a dramatic rise in the number of children participating in competitive sports. Adolescents involved in sports that require cutting, pivoting or body contact are at greatest risk for sustaining an anterior…
- Trial name
- NCT02316639
- Testing
- Neuromuscular Training
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Respiratory Distress Syndrome
NHFOV Versus NCPAP to Prevent Exubation Failure
The purpose of the study is to assess whether nasal high frequency ventilation (NHFV) is superior to nasal continuous positive pressure (nCPAP) to prevent tracheal intubation and mechanical ventilation in preterm infants less…
- Trial name
- NCT01852916
- Testing
- CPAP, NHFOV
- Where
- 2 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Respiratory Distress Syndrome
Impact of Different Modes of Noninvasive Ventilation on Regional Oximetry and Hemodynamics in Premature Newborn
The purpose of this study is to examine the blood flow and the delivery of oxygen to the brain and gut in preterm babies while they are supported with two modes of breathing machine and compare these two methods to see if one…
- Trial name
- NCT01942967
- Testing
- Echocardiography, Near Infrared Spectroscopy Monitoring
- Where
- 2 sites in Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Hypotension, Spinal Cord Injury
Effect of Tadalafil (Cialis) on the Cardiovascular System of Spinal Cord Injury (SCI) Males
To address the effect of tadalafil (Cialis) on the cardiovascular system of men with complete spinal cord injury at T-6 and above. The hypothesis is that tadalafil will cause significant hypotension in people with tetraplegia.
- Trial name
- NCT01067391
- Testing
- tadalafil
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Obstructive Sleep Apnea
Respiratory Drive on Obstructive Apnea
This study is being conducted to determine whether inhaling exhaled carbon dioxide is effective for the treatment of sleep apnea.
- Trial name
- NCT01961648
- Testing
- Rebreathing bag, Mask
- Where
- 2 sites in Canada
- Volunteers
- 13 people
- Sponsor
- University of Manitoba
Spinal Stenosis
Level of Activity in Lumbar Spinal Stenosis Patients Pre- and Post-surgery
The purpose of the proposed research is to explore the relationship between objectively measured physical activity and surgical intervention for lumbar spinal stenosis (LSS).
- Trial name
- NCT02154191
- Testing
- Surgical Intervention
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Radius Fractures
Reducing Range of Motion Deficits Post Radial Fracture
This a randomized controlled study to test the hypothesis that patients who perform in-cast exercises will have superior range of motion immediately post-cast removal, without a concomitant increase in complication rate when…
- Trial name
- NCT01262807
- Testing
- Exercises
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Manitoba
Complicated Urinary Infection
Urinary Tract Infection Study With the Antibiotic Levofloxacin Given at a Higher Dose Over a Shorter Period of Time
The purpose of the study is to compare the safety and effectiveness of the antibiotic levofloxacin by administering a higher dose of levofloxacin and using a shorter course of therapy.
- Trial name
- NCT00245791
- Testing
- Levofloxacin
- Where
- 3 sites in Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Generation of Reactive Oxygen Species, Intestinal Inflammation
Assessment of Complementary Feeding of Canadian Infants
With the recent recommendation from Health Canada to extend exclusive breast-feeding to 6 months of age there has arisen concern about what is the best solid food to introduce at that time.
- Trial name
- Infant Feeding (NCT01790542)
- Testing
- Iron fortified cereal, Iron fortified cereal with fruit, Meat
- Where
- Canada
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pregnancy
The Role of Timing of Dexamethasone Administration on Pain Scores and Quality of Recovery in Cesarean Section.
The purpose of our study was to evaluate the hypothesis that single dose dexamethasone given sixty minutes preoperatively reduces visual analog scale (VAS) pain scores and improves quality of recovery in patients undergoing…
- Trial name
- NCT02112422
- Testing
- Control, Intervention
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Spinal Stenosis
The Impact of Spinal Manipulation on Leg Movement in Lumbar Spinal Stenosis Patients
The objectives of the proposed research are to quantify the impact on motor performance of a single SM intervention on surgical waitlist patients with degenerative Lumbar Spinal Stenosis (LSS) using a recently established lower…
- Trial name
- NCT02118103
- Testing
- Spinal Manipulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University of Manitoba
Influenza, Human, Orthomyxoviridae Infections
DNA-based Influenza Vaccine in the Elderly
The purpose of this study is to determine whether FVH1, a DNA-based influenza vaccine, will be safe and generally well tolerated in healthy elderly adult volunteers and will result in greater immunogenicity when used to prime the…
- Conditions
- Influenza, Human, Orthomyxoviridae Infections, RNA Virus Infections, Virus Diseases
- Trial name
- NCT01587131
- Testing
- FVH1 - a DNA-based influenza vaccine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Personal Satisfaction
Evaluating the Clinical Efficacy and Safety of Colflex
This study is designed to test the safety and efficacy of Colflex, an oral spray created by Innotech Nutrition, on human subjects to measure changes on frequency/duration of colds and sore throats, as well as dental and oral…
- Trial name
- NCT02011035
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Brain Injuries
Rehabilitation Boot Camp: Intensive Balance and Mobility Therapy for People With Acquired Brain Injury
The purpose of this study is to determine 1. if it is practical to treat moderately to severely brain injured patients who have problems with their balance and mobility in a group "boot camp" (3 days a week, 6 hours/day for 4…
- Trial name
- NCT02019173
- Testing
- Boot Camp Balance Training
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Muscle Spasticity as a Result of Spinal Cord Injury
Effect of Cannabinoids on Spasticity and Neuropathic Pain in Spinal Cord Injured Persons
This study is being conducted to study the effect of nabilone (a synthetic cannabinoid)on spasticity in spinal cord injured persons.The study will be a phase 2, randomized, placebo-controlled crossover study.
- Trial name
- NCT01222468
- Testing
- nabilone 0.5 mg
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Manitoba
Apnea of Prematurity
Inhalation of Low Concentration of CO2 in Preterm Infants Not Responding to Caffeine for the Treatment of Apnea
In premature infants, apnea of prematurity is one of their major clinical problems. Caffeine is currently a worldwide therapy to reduce the number and severity of these apneas.
- Trial name
- NCT01911182
- Testing
- Inhalation of low concentration of CO2
- Where
- Canada
- Volunteers
- 7 people
- Sponsor
- University of Manitoba
Sleep Apnea
Outcome and Treatment of Complex Sleep Apnea
The purpose of the project is: 1. to determine the incidence of complex sleep apnea 2. to determine what percentage of cases will resolve over time with therapy with Continuous Positive Airway Pressure 3.
- Trial name
- NCT01137214
- Testing
- Non-invasive positive pressure ventilator
- Where
- Canada
- Sponsor
- University of Manitoba
Obesity, Hypercholesterolemia
Lentils as a Functional Food to Improve Glucose and Decrease Cardiovascular Risk
Compared to control foods, consumption of 3 cups of cooked lentils given weekly for 12 weeks will significantly improve glucose tolerance and lower LDL-cholesterol in individuals with high cholesterol and obesity.
- Trial name
- LEN-0-2012 (NCT01562171)
- Testing
- Cooked Lentils, Potato-Based Foods
- Where
- 2 sites in Canada
- Volunteers
- 102 people
- Sponsor
- University of Manitoba