Clinical trials: sponsored by University of Manitoba
Type 2 Diabetes Mellitus, Adolescent Obesity
A Study of the Effects of Exercise Intensity on Insulin Sensitivity in Overweight Youth
Background: The investigators know that exercise helps children develop strong bones and muscles and generally stay healthy. What is unclear however, is how much exercise a child needs to lower their risk of developing type 2…
- Trial name
- POWER (NCT00755547)
- Testing
- Aerobic Exercise Training
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Peripheral Arterial Disease
Effects of Canola Oil on Blood Vessel Function in Peripheral Arterial Disease
The fatty acid composition of canola oil will have beneficial acute and chronic effects on vascular function in individuals with peripheral arterial disease.
- Trial name
- NCT01250275
- Testing
- traditional canola oil, high oleic canola oil, soybean oil
- Where
- Canada
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Disease
Efficacy of High-oleic Canola and Flaxseed Oils for Hypercholesterolemia and Cardiovascular Disease Risk Factors
The purpose of this study is to assess the efficacy of high-oleic canola oil and a high-oleic canola/flaxseed oil blend as compared to a typical Western diet on plasma lipids, fatty acid profiles, and risk factors associated with…
- Trial name
- NCT00927199
- Testing
- High-Oleic Canola Oil, High-Oleic Canola/Flaxseed Oil Blend, Western Dietary Control
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Manitoba
Hyperlipidemia, Obesity
Metabolic Health Benefits of Dairy Protein
The purpose of this study is to evaluate the effects of regular low fat diary consumption on markers of cardiovascular (CV) and metabolic (cardiometabolic) health including body composition (% body fat, body weight), blood…
- Trial name
- NCT01761955
- Testing
- High Dairy
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hypoxia
Apneic Oxygenation Via Nasal Cannulae Prevents Arterial Hypoxemia
The purpose of the study is to evaluate the effectiveness of continuous oxygen provided by nasal prongs in preventing or delaying hypoxemia during the apneic period that occurs after induction of general anesthesia.
- Trial name
- NCT00782977
- Testing
- Nasal oxygen therapy
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
Healthy Volunteers
Krill Oil Study Compared to Fish Oil
The main purpose of the study is to evaluate the absorption of omega-3 fatty acids into the blood following consumption of krill oil compared with fish oil and placebo.
- Trial name
- Krill (NCT01323036)
- Testing
- Krill oil, Fish Oil
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Hemifacial Spasm
Hemifacial Spasm and Desflurane
Patients are chosen to participate in this study because they will undergo a particular type of brain surgery to treat their hemifacial spasm.
- Trial name
- HFS (NCT01726725)
- Testing
- desflurane
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Simplified Postoperative Radiographs
A Prospective Trial Comparing the Cost of Post Operative X-rays for Fractures Treated With Stable Internal Fixation
The standard post-operative radiographic protocol for the monitoring of fractures at HSC includes post-operative in hospital radiographs as well as radiographs at the two week follow up appointment.
- Trial name
- SPOR (NCT01644344)
- Testing
- No-Xray, Xray
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- University of Manitoba
Patellofemoral Syndrome, Patellofemoral Pain Syndrome
Use of Wii Fit (TM) to Increase Compliance With Home Exercises in Treating Patellofemoral Syndrome
To determine the utility of the Wii Fit TM interactive video game program in patellofemoral symptom resolution, development of increased muscle strength and flexibility as a result of increased compliance with home exercises in…
- Conditions
- Patellofemoral Syndrome, Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
- Trial name
- NCT01007643
- Testing
- Wii Fit (TM) Interactive Video Game, Traditional Home Exercise Program
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- University of Manitoba
Neuropathic Pain, Multiple Sclerosis
Efficacy and Safety Evaluation of Nabilone as Adjunctive Therapy to Gabapentin for the Management of Neuropathic Pain in Multiple Sclerosis
The purpose of this study is to determine whether nabilone (Cesamet) when used as an adjunctive agent with gabapentin (Neurontin) provides significantly improved pain relief over gabapentin alone for the management of neuropathic…
- Trial name
- NCT00480181
- Testing
- nabilone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Neuropathic Pain, Multiple Sclerosis
Neuropathic Pain Assessment Comparing Pregabalin and Paroxetine in Management of MS-induced Neuropathic Pain
This is a comparative drug trial involving patients with clinically definite Multiple Sclerosis and documented neuropathic pain. Patients will be randomized to receive treatment with either paroxetine or pregabalin.
- Trial name
- NCT00291148
- Testing
- paroxetine, pregabalin
- Where
- Canada
- Volunteers
- 75 people
- Sponsor
- University of Manitoba
Osteoporosis
A Randomized Controlled Trial of a Bone Density Decision Aide
This research study is being conducted to determine if a modified bone mineral density (BMD) test report that contains additional fracture risk information will be a useful physician decision aide in selecting patients for…
- Trial name
- NCT00285168
- Testing
- Bone Density Decision Aide
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Complete Edentulism
Within-subject Comparison of Mandibular Overdentures Retained by 1,2,or 3 Implants
This research is being done to find out the ideal number of implants/attachments required to provide adequate stability of dentures during function.
- Trial name
- NCT01566227
- Testing
- Questionnaire
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Rheumatoid Arthritis
Treatment of TNFa Naive Patients With Poor Prognosis Rheumatoid Arthritis
The purpose of this study is to determine how well Rituximab works in early stages of disease and the effects it has on an inflamed joint and blood cells.
- Trial name
- NCT00963703
- Testing
- Rituximab
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Manitoba
Rotator Cuff Tear
Workers Compensation Board: Rotator Cuff Tear Management
The overall goal of this proposed randomized study is to determine if surgery at the time of diagnosis or rehabilitation +/- surgery (i.e. surgery only when rehabilitation fails) results in shorter times to claim closure.
- Trial name
- NCT01498198
- Testing
- Rotator Cuff Repair Surgery, Non Operative Treatment
- Where
- Canada
- Volunteers
- 144 people
- Sponsor
- University of Manitoba
Hypercholesterolemia
Efficacy of Plant Sterol-Fortified Dairy Product on Plasma Lipid and Plant Sterol Concentrations in Humans
The aim of this clinical study was to determine the efficacy on plasma cholesterol-lowering of a water dispersible formulation of plant sterol (WD-PS) preparation versus plant sterol esters (PS-ester), consumed within dairy…
- Trial name
- NCT01478789
- Testing
- WD-PS intervention phase, PS-Ester intervention phase
- Where
- Canada
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Lumbar Herniated Disc
Evaluation of Minimally Invasive Microdiscectomy Versus Conventional Open Microdiscectomy For Lumbar Herniated Disc
Overall Objective: To evaluate pain and functional status of patients undergoing surgical correction for lumbar herniated disc, pre- and post-surgery, using subjective (VAS, Oswestry, PSQI, Patient Expectation), as well as…
- Trial name
- NCT00927056
- Testing
- Microdiscectomy
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Lumbar Spinal Stenosis
Effects of a Walking Program on Functional Status of Post-Surgical Lumbar Spinal Stenosis Patients
Overall Objective: To evaluate the efficacy of an interventional walking program on the quality of life and functional status of patients with Lumbar Spinal Stenosis, post-surgery, using subjective (VAS, ODI, RMDQ, SF-36), and…
- Trial name
- NCT00958490
- Testing
- Walking program
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Healthy
Efficacy of Two Yogurt Formulations in Healthy Humans
This study is to evaluate the safety and efficacy of consumption of: L.Ruteri containing yogurt, L.Fermentum containing yogurt VERSUS placebo on plasma lipids, as well as gastrointestinal microflora distribution in hyperlipidemic…
- Trial name
- MPH (NCT01409668)
- Testing
- L. Amylovorus, L. Fermentum
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Mobility Limitation
Effects of Game-based Balance Exercise for Older Adults With Fall History
Due to the many problems associated with reduced balance and mobility, providing an effective and engaging rehabilitation regimen is essential to progress recovery from impairments and to help prevent further degradation of motor…
- Trial name
- NCT01381237
- Testing
- game-based balance exercises
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba