Clinical trials: sponsored by University of Manitoba
Influenza A Virus
Trial Comparing High Versus Standard Dose Oseltamivir in Severe Influenza Infection in ICU
Primary Objectives: The primary objective of the trial is to compare the antiviral efficacy of a 10 day course of standard (75 mg bid) and high-dose (225 mg bid) oseltamivir (or equivalent doses in mild-moderate renal failure) in…
- Trial name
- ROSII (NCT01010087)
- Testing
- Oseltamivir
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- University of Manitoba
Cardiovascular Disease
Cholesterol Metabolism in Heterozygous Phytosterolemia
The purpose of the study is to examine the effect of plant sterols on cholesterol absorption and synthesis in people with heterozygous phytosterolemia.
- Trial name
- NCT01102647
- Testing
- phytosterol ester
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Phantom Limb Pain, Neuropathic Pain
Nabilone for the Treatment of Phantom Limb Pain
The purpose of this proposed study is to conduct a randomized double-blind placebo controlled trial assessing the benefit of nabilone in pain management and improvement of quality of life in patients with phantom limb pain.
- Trial name
- NCT00699634
- Testing
- Nabilone
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba
Zone 2 Flexor Tendon Lacerations of the Hand
The Effects of a Stainless Steel Suture MGH Flexor Tendon Repair Coupled With Early Aggressive Range of Motion Rehabilitation: a Randomized Controlled Trial
The investigators are comparing the combination of a stainless steel repair and aggressive early active range of motion rehabilitation protocol for flexor tendon lacerations in the hand with a current, accepted treatment offered…
- Trial name
- NCT01344980
- Testing
- Stainless steel suture, Polypropylene suture, Aggressive early active range of motion rehabilitation
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cervical Radiculopathy
Oral Dexamethasone for the Treatment of Cervical Radiculopathy
The purpose of this study is to determine whether dexamethasone is effective in the treatment of pain and disability resulting from a compressed spinal nerve in the neck (cervical radiculopathy).
- Trial name
- NCT00308594
- Testing
- Dexamethasone
- Volunteers
- 100 people
- Sponsor
- University of Manitoba
Free Flap Post Mastectomy
Goal Directed Fluid Therapy in Free Flap Patients
Fluid management of surgical patients has changed dramatically in recent years. Recent studies have shown that so called 'restrictive' fluid strategies can improve outcomes such as length of stay and time to fitness for…
- Trial name
- NCT00869297
- Testing
- Goal Directed Fluid Administration, Control
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Development of Control of Breathing
Effects of Targeting Lower Arterial Oxygen Saturations on the Development of Control of Breathing in Very Preterm Infants
To determine whether targeting lower arterial oxygen saturations from the day of birth alters the early (first 3 months) postnatal development of the control of ventilation and the hypercapnic and hyperoxic responses in very…
- Trial name
- NCT00573053
- Testing
- Oxygen saturation range
- Where
- 2 sites in Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Analgesia
Analgesia After Total Knee Arthroplasty
The recovery from knee replacement surgery often involves a significant amount of pain. The best way to prevent/treat this pain is unknown.
- Trial name
- NCT00869037
- Testing
- Periarticular Injection, CFNB + Posterior Capsular Injection
- Where
- Canada
- Volunteers
- 90 people
- Sponsor
- University of Manitoba
HIV Infections
Study of Cell Phone SMS Messages for Prevention of Maternal to Child Transmission of HIV
Optimal development of sustainable health systems must use locally relevant infrastructure. Mobile phone technology, driven primarily by local market forces rather than foreign assistance, is spreading rapidly through African…
- Trial name
- NCT01157442
- Testing
- cell phone sms text messaging
- Where
- Kenya
- Volunteers
- 856 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Psoriasis
Efficacy of Two Algae Formulations on Lipid Metabolism, Inflammation and Oxidative Stress Status in Individuals With Psoriasis
Our overall goal is to evaluate the safety and efficacy of consumption of two algae formulations compared to a placebo on: degree of severity of skin lesions, plasma lipid levels, as well as other health-related markers, in…
- Trial name
- PCA (NCT01045395)
- Testing
- Corn starch, Unique Marine Algae Concentrate (UMAC), Golden brown algae
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Postoperative Pain.
The Effects of Peri-operative Pregabalin Administration on Post-operative Analgesia in Patients Undergoing Coronary Bypass Grafting
We hypothesize that the perioperative administration of pregabalin will significantly decrease pain scores and post-operative opioid requirements for patients undergoing coronary artery bypass grafting, and reduces the incidence…
- Trial name
- NCT00623285
- Testing
- Pregabalin
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Prostate Cancer
Exercise in Men With Prostate Cancer
The purpose of this pilot study is to compare a walking exercise program (Exercise Group) to standard medical care (Control Group) in prostate cancer survivors receiving androgen depletion therapy (ADT).
- Trial name
- NCT00834392
- Testing
- Exercise
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Prostate Cancer
Exercise and Cognitive-psychosocial Functions in Men With Prostate Cancer Receiving Androgen Depletion Therapy
The objective of the proposed research is to determine the efficacy of a home-based walking exercise program in promoting cognitive-psychosocial functions of men with prostate cancer receiving androgen depletion therapy (ADT).
- Trial name
- NCT00856102
- Testing
- Exercise, Control
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Manitoba
Premature Infants
The Impact of Nasogastric Indwelling Versus Oral Intermittent Tube Feeding Methods on Premature Infants
This clinical pilot trial is being conducted to learn more about the infant's feeding behavior while being fed by indwelling nasogastric tube placement or by intermittent oral tube placement.
- Trial name
- NCT00798824
- Testing
- Indwelling nasogastric tube placement, Intermittent orogastric tube placement, Nasogastric tube
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Cardiovascular Disease
Effect of Pulse Fractions on Indices on Cardiovascular Disease and Diabetes Risk Factors
The purpose of this study is to determine if whole and fractionated yellow pea flour, administered at USDA recommended dosages (50 g/day), improve risk factors associated with cardiovascular disease and diabetes.
- Trial name
- NCT00839774
- Testing
- Whole yellow pea flour, Fractionated pea flour, White wheat flour
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- University of Manitoba
HIV, AIDS
Cell Phone Intervention to Support Antiretroviral Therapy (ART) Adherence in Kenya
A clinical study to evaluate the use of cell phones to support drug adherence and follow-up of patients taking antiretroviral therapy (ART) for treatment of HIV.
- Conditions
- HIV, AIDS, HIV Infections
- Trial name
- NCT00830622
- Testing
- Cell Phone Intervention
- Where
- Kenya
- Volunteers
- 536 people
- Sponsor
- University of Manitoba
Critical Illness, Burnout, Professional
Effect of Around the Clock Intensivist Coverage on Intensive Care Unit (ICU) Outcomes
Intensive Care Units (ICU) are an important, but troubled, part of modern health care systems. While it seems likely that both the technical and structural elements of ICU care are important determinants of relevant ICU outcomes…
- Conditions
- Critical Illness, Burnout, Professional, Education, Medical, Patient Satisfaction
- Trial name
- NCT01146691
- Testing
- Alternative Intensivist staffing models
- Where
- 2 sites in Canada
- Volunteers
- 627 people
- Sponsor
- University of Manitoba
Critical Illness, Burnout, Professional
Multicenter Intensivist Weekend Scheduling Study
The care of critically ill patients in Intensive Care Units (ICUs) is an important part of modern health care systems. However, ICU care suffers from similar problems as the rest of the health care system.
- Trial name
- NCT01145443
- Testing
- Alternative Intensivist staffing models.
- Where
- 4 sites in United States
- Volunteers
- 1,945 people
- Sponsor
- University of Manitoba
Apnea of Prematurity
CO2 Inhalation as a New Treatment Modality for Apnea of Prematurity
The objective of the present proposed study is to discover whether, in the nursery setting, administration of low concentration inhaled CO2 (0.8%) for a prolonged period (3 days) can make breathing more regular with less apneic…
- Trial name
- NCT01066728
- Testing
- CO2 inhalation, Theophylline
- Where
- 2 sites in Canada
- Volunteers
- 87 people
- Sponsor
- University of Manitoba
Healthy
Barley Tortillas Study in Healthy Volunteers
The variation in starch and fibre composition of prepared barley tortillas will have a significant effect on glycemic response.
- Trial name
- NCT00831285
- Testing
- food product
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba