Clinical trials: sponsored by University of Manitoba
Chronic Kidney Disease
Integrating Risk-based Care for Patients With CKD
Chronic kidney disease (CKD) and its end stage of kidney failure are major public health problems in Canada and worldwide. In the primary care setting, accurate prediction of the risk of kidney failure in patients with CKD can…
- Trial name
- NCT03365063
- Testing
- Active Knowledge Translation
- Where
- 2 sites in Canada
- Volunteers
- 5,600 people
- Sponsor
- University of Manitoba
Stress, Psychological, Parenting
Supporting Parent and Child Engagement
The COVID-19 pandemic and measures aimed at reducing the spread of the virus have created unique challenges and stresses for Canadian families.
- Conditions
- Stress, Psychological, Parenting, Covid19
- Trial name
- SPACE (NCT04925258)
- Testing
- SPACE Parenting Program
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- University of Manitoba
Depression, Child Development
Building Regulations in Dual Generations at KIDTHINK
Neurodevelopmental disorders (NDDs) such as attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and intellectual disability (ID) are the most frequently diagnosed disability in children, accounting…
- Conditions
- Depression, Child Development, Self-regulation
- Trial name
- NCT04893850
- Testing
- BRIDGE Therapy Program, Community Services as Usual Clinical Referral list
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Aerobic Exercise
Acute Cardiovascular Responses to Two Types of Exercise
The purpose of this research was to explore potential differences in acute cardiovascular responses between two conditions: 1) moderate-intensity cycle ergometer exercise; and 2) moderate-intensity cycle ergometer exercise with…
- Trial name
- NCT07016594
- Testing
- Aerobic exercise
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pediatric Readiness
Pediatric Readiness Intervention in Manitoba
The goal of this clinical trial is to improve emergency care of children in Manitoba by increasing the weighted pediatric readiness scores (WPRS) of the general EDs through the implementation of provincially derived…
- Trial name
- NCT06257524
- Testing
- Education and training
- Where
- Canada
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Benign Prostate Hypertrophy(BPH)
Trial to Assess the Efficacy and Safety During Convective Radiofrequency Water Vapor Thermal Therapy (REZUM) for Benign Prostate Hyperplasia
The primary aim of the study is to show that methoxyflurane-lorazepam-percocet combination administrated 'per os' is non inferior to deep intravenous sedation in achieving analgesia during Rezum convective radiofrequency water…
- Trial name
- NCT07017452
- Testing
- Methoxyflurane - Penthrox, Control, Percocet Pill
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Benign Prostate Hypertrophy(BPH)
Investigating the Adjunctive Use of Mirabegron in the Early Post-Rezum Procedure Period
The investigators propose conducting a randomized controlled trial at the Men's Health Clinic to evaluate whether patients who start and continue mirabegron postoperatively after undergoing Rezum therapy experience enhanced…
- Trial name
- NCT07017439
- Testing
- Beta-3 agonists (Mirabegron/Myrbetriq)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Chronic Kidney Disease, Diabetes
Kidney Check: Diabetes, Blood Pressure & Kidney Health Checks & Care in Indigenous Communities.
Faced with limited access to preventative health care services, Indigenous people living in rural and remote communities are at a higher risk of Chronic Kidney Disease (CKD) and kidney failure, when compared to the general…
- Conditions
- Chronic Kidney Disease, Diabetes, Hypertension
- Trial name
- NCT03595267
- Testing
- Point-of-care screening
- Where
- 3 sites in Canada
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Anhedonia
Promoting Positive Emotional Functioning in Police and Military Populations
This study will examine whether actively serving and veteran members of the Canadian Armed Forces (CAF) and Royal Canadian Mounted Police (RCMP) who complete a treatment targeting anhedonia symptoms and amplifying positive…
- Trial name
- NCT06035562
- Testing
- PVSET
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Manitoba
Chronic Migraine
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
Chronic headaches are a major cause of disability among adolescents. Cannabis products have supported the management of headaches in adults and may play a role in pediatric chronic pain.
- Trial name
- CAN-CHA (NCT05337033)
- Testing
- MPL-001
- Where
- 3 sites in Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
COPD, Interstitial Lung Disease
Effect of Pulmonary Telerehabilitation and Telemonitoring for Patients With Chronic Respiratory Diseases
This research study is being conducted to evaluate the feasibility of using technology to deliver a remote home exercise program and assess the health outcomes of patients with chronic lung diseases.
- Trial name
- NCT05824910
- Testing
- Exercise program (virtual/remote)
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- University of Manitoba
COVID-19
Self-management of Post COVID-19 Syndrome Using Wearable Biometric Technology
The main objective of this pilot study is to evaluate the impact of a self-management intervention using wearable biometric technology on post-COVID-19 syndrome.
- Trial name
- NCT05507190
- Testing
- Self-management of post COVID-19 respiratory outcomes
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Colo-rectal Cancer, Colon Polyp
Optimizing Timing of Follow-up Colonoscopy
Overall Objective: To optimize timing of surveillance colonoscopy. Principal research question and specific aims: To assess the impact of access to a hand-held application on the timing of surveillance colonoscopy.
- Conditions
- Colo-rectal Cancer, Colon Polyp, Colonic Polyp, Rectal Polyp
- Trial name
- NCT04889352
- Testing
- Access to colonoscopy web app
- Where
- 2 sites in Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Inflammatory Bowel Diseases, Ulcerative Colitis
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our…
- Trial name
- NCT05615779
- Testing
- Randomized B-fructan diet, Personalized pectin diet, Personalized B-fructan diet
- Where
- 2 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Maternal Depression, Self-Regulation, Emotion
Building Regulation in Dual Generations 2022-2025
This randomized control trial aims to investigate whether a novel intervention, the "Building Regulation in Dual Generations (BRIDGE)" program, improves mental wellness and parenting practices among mothers of 3 to 5-year-old…
- Conditions
- Maternal Depression, Self-Regulation, Emotion, Child Mental Disorder, Child Development
- Trial name
- BRIDGE (NCT05959538)
- Testing
- Building Regulation in Dual Generations (BRIDGE), Dialectical Behavioural Therapy Skill Training
- Where
- Canada
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Sleep
Investigating the Efficacy of Sleepgift Blanket on Sleep Quality and Heart Health
Exposure to electromagnetic field (EMF) emitted by mobile phones and devices with WIFI is on the rise and so is the EMF effects on sleep quality and well-being of individuals with high exposures to EMF.
- Trial name
- NCT05463302
- Testing
- Active sleepgift blanket
- Where
- Canada
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy
Normal Brain Imaging Database for Brain Disorder Studies
Healthy volunteers will be recruited. All subjects will be tested a battery of neuropsychological tests, then undergo fluorodeoxyglucose-positron emission tomography (PET) and magnetic resonance imaging (MRI).
- Trial name
- Normal_tDCS (NCT03027869)
- Testing
- transcranial direct current stimulation
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Temporomandibular Joint Disorders, Magnetic Resonance Image
Effectiveness of Handheld Ultrasound for Diagnosing Patients with TMD
The aim of this research is to add to the limited body of knowledge comparing the effectiveness of ultrasound (US) to MRI diagnoses in patients with TMJ disorders.
- Conditions
- Temporomandibular Joint Disorders, Magnetic Resonance Image, Handheld Ultrasound
- Trial name
- NCT05324826
- Testing
- Butterfly Network handheld ultrasound
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Mental Health, Social Isolation
A Mixed Methods Randomized Controlled Trial Evaluating the Hans Kai Program
The Hans Kai trial is a mixed methods randomized controlled trial evaluating the effectiveness of the peer-led health promotion Hans Kai program for Canadian adults with or without chronic health conditions.
- Conditions
- Mental Health, Social Isolation, Loneliness, Health-Related Behavior
- Trial name
- NCT03949725
- Testing
- Hans Kai Program
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Chronic Kidney Diseases
Resistant Starch Prebiotic Effects in Chronic Kidney Disease
In patients with Chronic Kidney Disease (CKD), there is a buildup of nitrogenous uremic toxins of gut microbiome origin, which can contribute to uremic symptoms, reduced quality of life, and earlier progression to dialysis.
- Trial name
- ReSPECKD (NCT04961164)
- Testing
- Resistant Potato Starch, Corn Starch, Corn Starch, Resistant Potato Starch
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- University of Manitoba