Clinical trials: sponsored by University of Manitoba
Dementia, Mild
Investigational Dementia Treatment Study
This research investigates the effect of active versus sham tACS paired with cognitive exercises in a regimen protocol of weeks, everyday.
- Trial name
- tACS (NCT05203523)
- Testing
- transcranial alternative current stimulation (tACS), cognitive exercises
- Where
- 2 sites in Canada
- Volunteers
- 73 people
- Sponsor
- University of Manitoba
Healthy Diet, Healthy
A Multidisciplinary Investigation of Cardiovascular Benefits of Wild Rice
In this study 24 adult males and adult females, with overall healthy condition, will consume approximately 30 grams of wild rice every day for 28 days.
- Trial name
- NCT04119791
- Testing
- wild rice
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Arterial Stiffness
Postprandial Effects of Bean and Whole Grain Consumption on Arterial Stiffness
This is a single site, single-blinded, controlled randomized crossover clinical trial designed to compare the effects of black beans or whole grains or white rice at breakfast on postprandial vascular responses in males and…
- Trial name
- NCT05818358
- Testing
- black beans, wheat berries, white rice
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba
Power Assisted Device, Children, Only
Power-assisted Mobility for Children
In this project, we intend to explore the experience of children who use a manual wheelchair (MWC), their parent/guardian, and their prescribing therapist after the child is exposed to a power-assist device (PAD) attached to…
- Trial name
- NCT06159400
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Epilepsy, Sleep
Lemborexant Treatment of Insomnia Linked to Epilepsy
The goal of this clinical trial is to assess whether Lemborexant can improve sleep in patients with epilepsy.
- Trial name
- L'ÉTOILE (NCT06262594)
- Testing
- Lemborexant
- Where
- 2 sites in United States, Canada
- Volunteers
- 26 people
- Sponsor
- University of Manitoba
Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level
Neuromodulation With Spinal Stimulation Methods
This is a pilot research study to test the protocols needed for transcutaneous spinal electrical stimulation in persons living with spinal cord injury (SCI). Up to 24 participants will be enrolled.
- Conditions
- Spinal Cord Injuries, Spinal Cord Injury at C5-C7 Level, Paraplegia, Spinal, Paraplegia, Incomplete
- Trial name
- NCT06272279
- Testing
- spinal stimulation-DCS, spinal stimulation-EPS
- Where
- 2 sites in Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Erectile Dysfunction
Evaluating the Efficacy of Platelet-Rich-Plasma (PRP) for Erectile Dysfunction
There is great interest in restorative therapies (platelet-rich plasma (PRP) injections, shockwave therapy and stem cell therapy) for ED given their non-invasive nature.
- Trial name
- NCT06264635
- Testing
- Platelet-Rich-Plasma, Saline
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Feasibility, Anxiety State
Virtual Reality for Urological Procedures
It is standard practice for most cystoscopies and vasectomies in an office or outpatient setting to be performed under local anesthesia while the patient is awake and conscious.
- Conditions
- Feasibility, Anxiety State, Pain, Satisfaction, Patient
- Trial name
- NCT06534086
- Testing
- Virtual reality (VR) guided meditation therapy, Treatment as usual
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Competence, Consumer Vocational Outcomes
Effects of Practitioner Competency and Impact on Vocational Outcomes
The following proposal aims to determine if increasing the competency of mental health practitioners (e.g., social workers, occupational therapists, psychiatric nurses) in the area of vocational rehabilitation (VR) helps their…
- Conditions
- Competence, Consumer Vocational Outcomes, Consumer Satisfaction
- Trial name
- NCT06778200
- Testing
- client interview, practitioner responses
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Crohn Disease, Ulcerative Colitis
Bowel Preparation for Colonoscopy Among Individuals With Crohn's and Ulcerative Colitis Disease.
The purpose of this study is to compare how effective and how tolerable two different bowel preparation laxatives are for colonoscopy.
- Trial name
- NCT06298461
- Testing
- KleanLyte, Bi-PegLyte
- Where
- Canada
- Volunteers
- 418 people
- Sponsor
- University of Manitoba
ARDS, Human
Depth of Sedation and Its Impact on Cerebrovascular Reactivity in Acute Respiratory Distress Syndrome: a Pilot Analysis
Investigation of the feasibility of monitoring processed transcutaneous electroencephalography (EEG), a method of interpreting brain activity, and near-infrared spectroscopy (NIRS), a method of determining levels of tissue…
- Trial name
- NCT05847634
- Testing
- Masimo O3 NIRS cerebral oximetry and SedLine processed EEG
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Chronic Kidney Disease 5D
Feasibility of a Randomized Cluster Trial for Blood Pressure Targets in In-centre Hemodialysis Units
High blood pressure in people receiving hemodialysis is known to contribute to heart disease and heart-related death from strokes, heart failure, left ventricular hypertrophy (which is a thickening of the heart wall that makes it…
- Trial name
- NCT06695611
- Testing
- Increase systolic blood pressure, Decrease systolic blood pressure
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Skeletal Muscle
Skeletal Muscle Myokine Response to Acute Eccentric Exercise
The purpose of this study is to evaluate the acute local skeletal muscle inflammatory response to thigh muscle (quadriceps) eccentric muscle actions. Eccentric muscle actions occur when the muscle is lengthening as it contracts.
- Trial name
- NCT06677749
- Testing
- Eccentric resistance-exercise
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Obesity
A Pilot Study Evaluating a Clinically Managed Weight Loss Program
This is a pilot study evaluating a clinically managed weight loss program. The program consists of a 17-week weight loss program which involves a multidisciplinary team where personalized interventions are given to participants…
- Trial name
- NCT04290910
- Testing
- Weight Loss Program
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of Manitoba
Blood Glucose
Glycemic Response to Wild Rice and Wild Rice Blends in Humans Study
The goal of this clinical trial is to test the effects of wild rice and wild rice blends compared to other rice on glycemic control and evaluating factors that influence glycemic response to wild rice in healthy individuals.
- Trial name
- EFGW (NCT05976633)
- Testing
- Whole white rice (control), Whole brown rice, Whole wild rice
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
High Risk Non-cardiac Surgery, Death
Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery
Cerebral desaturations occur frequently in patients undergoing non-cardiac surgery. The definition of what constitutes a cerebral desaturation, the incidence of the phenomenon, the association between desaturations and…
- Conditions
- High Risk Non-cardiac Surgery, Death, Delirium, Kidney Injury
- Trial name
- NCT01838733
- Testing
- Observational study
- Where
- Canada
- Volunteers
- 146 people
- Sponsor
- University of Manitoba
Neck Pain, Psychomotor Disorders
Effectiveness of Dry Needling Shoulder Muscles on a Head Turning Task in Participants Aged 30-45 With Neck Pain
The goal of this clinical trial is to compare the immediate effects of stimulating shoulder muscles with an acupuncture needle (dry needling) on people from thirty to forty-five years old with recurrent neck pain.
- Trial name
- NCT05846022
- Testing
- Dry Needling
- Where
- Canada
- Volunteers
- 36 people
- Sponsor
- University of Manitoba
Peri-Implantitis and Peri-implant Mucositis
Effectiveness of Zirconia Glaze Removal and Polish in the Treatment of Peri-implant Mucositis
This clinical trial is being conducted to study peri-implant mucositis (inflammation in the gums around dental implant that does not extend into the implant-supporting bone).
- Trial name
- NCT06619158
- Testing
- Crown modification
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of Manitoba
Open Fracture, Trauma
Powdered Intrawound Vancomycin in Open Fractures Trial
The purpose of this randomized control trial is to compare the rate of post-operative infection in patients with open fractures in upper or lower extremity long bones randomized to receive intra-operative intrawound topical…
- Conditions
- Open Fracture, Trauma, Infection, Surgical Site, Fractures, Open
- Trial name
- PIVOT (NCT06504992)
- Testing
- Vancomycin 1000 MG
- Where
- Canada
- Volunteers
- 350 people
- Sponsor
- University of Manitoba
Self-Compassion, Physical Inactivity
A Single-arm Pilot and Feasibility Study of the CALM Hearts Intervention
The primary aims of this study are to explore the feasibility, acceptability, and safety, of the Compassionate And Loving Mindset towards heart health risk (CALM Hearts) intervention.
- Conditions
- Self-Compassion, Physical Inactivity, Cardiovascular Diseases
- Trial name
- NCT06576349
- Testing
- Compassionate And Loving Mindset towards Heart Health Risk (CALM Hearts) Intervention
- Where
- Canada
- Volunteers
- 11 people
- Sponsor
- University of Manitoba