Clinical trials: sponsored by University of Manitoba
Spinal Cord Injuries, Spinal Cord Diseases
Non-invasive Spinal Cord Stimulation After Spinal Cord Injury
Spinal cord injury (SCI) is a central nervous system injury that often leads to motor dysfunction. Non-invasive electrical stimulation of the spinal cord has been recognized as a potential method of reactivating lost spinal…
- Trial name
- SCI-ES-WALK (NCT06260735)
- Testing
- Trans-spinal electrical stimulation, Electrical muscle activation, Treadmill walking
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- University of Manitoba
Scrotum Disease, Hydrocele Male
Efficacy of EMLA Cream Assisted Loco-sedation for Office-based Andrology Procedures
Scrotal, urologic surgery has traditionally been conducted in the hospital setting, typically with the use of sedation, spinal anesthesia or general anesthesia.
- Conditions
- Scrotum Disease, Hydrocele Male, Spermatocele, Scrotal Hematocele
- Trial name
- NCT06242977
- Testing
- Eutectic mixture of local anesthetics (EMLA; Astra Pharmaceutical Products Inc., Westborough, MA), Control cream
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Bowel Ileus, Flatus
Chewing Gum on Postoperative Ileus in Children
Traditional postoperative care has been challenged recently to improve and speedup recovery (including the return of bowel function) such that patients can be discharged to home more quickly.
- Trial name
- GUM_1 (NCT03666377)
- Testing
- Gum chewing
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Pregnancy Early
Assessing Gestational Age in First Trimester Pregnancies Using Ultrasound
The objective of this study is to assess equivalency of the transabdominal Clarius handheld wifi C3 ultrasound (which uses Bluetooth to locate the ipad Mini 5 and then uses wifi direct to show the images) to the current standard…
- Trial name
- NCT03957200
- Where
- 2 sites in Canada
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Traumatic Brain Injury
Early Diagnosis of Mortality Using Admission CT Perfusion in Severe Traumatic Brain Injury Patients (ACT-TBI Study)
Background: Severe traumatic brain injury (TBI) is a principal cause of post-injury hospitalization, disability, and death throughout the world.
- Trial name
- ACT-TBI (NCT04318665)
- Testing
- CT Perfusion
- Where
- 4 sites in Canada
- Volunteers
- 200 people
- Sponsor
- University of Manitoba
Cardiac Arrest
CT Perfusion (CTP) for Assessment of Poor Neurological Outcome in Comatose Cardiac Arrest Patients
ABSTRACT Brief Overview: Neurological assessment of comatose cardiac arrest patients (CCAP) is challenging because most of these patients are treated with sedatives and therapeutic hypothermia that prevent complete…
- Trial name
- CANCCAP (NCT04323020)
- Testing
- CT Perfusion
- Where
- Canada
- Volunteers
- 91 people
- Sponsor
- University of Manitoba
COVID-19
Pulmonary Rehabilitation Post-COVID-19
The main objective of this pilot study was to evaluate the feasibility, safety, and satisfaction of a remote interdisciplinary PR program delivered using two exercise approaches (video conference and self-directed) on the…
- Trial name
- NCT05003271
- Testing
- Exercise program (virtual/remote)
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Cancer
Urinary Excretion of Acetylamantadine by Cancer Patients
The investigators have determined that the drug amantadine hydrochloride is metabolized by acetylation by a specific enzyme named spermidine/spermine N-acetyltransferase (SSAT). This enzyme is increased in cancer cells.
- Trial name
- NCT00755898
- Testing
- Ingestion of a 200 mg dose of amantadine hydrochloride
- Where
- Canada
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
End Stage Renal Disease, Pruritus
DIalysis Symptom COntrol-Pruritus Outcome Trial
The purpose of this study is to test whether or not a medication called nabilone, which is a synthetic (non-natural) medication derived from cannabis, compared to placebo improves symptoms of itch in hemodialysis as measured by…
- Trial name
- DISCO-POT (NCT05180968)
- Testing
- Nabilone 0.5 MG Oral Capsule
- Where
- 2 sites in Canada
- Volunteers
- 14 people
- Sponsor
- University of Manitoba
Older Adult Manual Wheelchair Users
Enhancing Participation In the Community by Improving Wheelchair Skills: Phase 2
The purpose of this project is to conduct a pilot study of the EPIC WheelS wheelchair skills home training program for older adults in preparation for a third phase feasibility study.
- Trial name
- EPIC WheelS (NCT01644292)
- Testing
- EPIC WheelS
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- University of Manitoba
Cancer, Epilepsy
Real World Evidence on the Use of Medical Cannabis in Pediatrics
CAN-RWE is an observational study that is following 500 children who have authorizations for medical cannabis for two years from across Canada.
- Conditions
- Cancer, Epilepsy, Neurodevelopmental Disorders
- Trial name
- CAN-RWE (NCT05863910)
- Testing
- Medical Cannabis
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- University of Manitoba
Mobility Limitation
Training to Enhance Adaptation and Management for Wheelchair Users (TEAMWheels)
The purpose of this study is to evaluate the effect of a 1-month, peer-led eHealth training program (TEAM Wheels) on satisfaction with activity participation and related rehabilitation outcomes among individuals transitioning to…
- Trial name
- TEAMWheels (NCT04090177)
- Testing
- TEAM Wheels
- Where
- 3 sites in Canada
- Volunteers
- 54 people
- Sponsor
- University of Manitoba
Lower Back Injury
Implementation of a Fitness Education and Training Program to Support Safe Patient Handling and Safe Lifting
This project involves the delivery of education and training sessions to Seven Oaks General Hospital (SOGH) staff, with the goal of workplace injury prevention.
- Trial name
- NCT05834959
- Testing
- An Educational and Training Program
- Where
- Canada
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Communication
A Pragmatic Feasibility Trial to Promote Student Perspective-Taking on Client Physical Activity: A Collaborative Project
This mixed-methods parallel two-arm trial assessed the feasibility, appropriateness, and acceptability of a theoretically-informed intervention designed to improve perspective-taking skills in preparation for a future definitive…
- Trial name
- NCT06123507
- Testing
- Student practitioner perspective-taking intervention
- Where
- Canada
- Volunteers
- 163 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Diabetic Retinopathy, Type 2 Diabetes
Enriched Eggs for Retina Health in Type 2 Diabetes
Diabetes mellitus has been declared a major public health issue. Among the complications of the disease, retinopathy can have a significant impact on mobility and quality of life for individuals living with diabetes.
- Trial name
- NCT04496817
- Testing
- Docosahexaenoic Acid and Lutein Enriched Eggs, Regular Eggs
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
HIV
Inducing Immune Quiescence the Genital Tract With ASA
There are 33.4 million individuals living with HIV/AIDS worldwide. Despite successful HIV prevention strategies such as condom use and reduction of sexual partners, HIV continues to spread at an alarming rate.
- Trial name
- IIQ-2 (NCT03629327)
- Testing
- ASA 81mg, Control Group, ASA 325mg
- Where
- Kenya
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Osteoarthritis, Knee, Chronic Knee Pain
Comparison Between Ultrasound-Guided Genicular Nerve Phenol Neurolysis and Intra-articular Steroid Injections
Genicular nerve neurolysis (GN) constitutes a relatively novel technique, whereby different chemical compounds (i.e. alcohol, phenol) are injected in close proximity to the genicular nerves of the knee joint, with the intention…
- Trial name
- NCT06000709
- Testing
- 6% aqueous phenol, MethylPREDNISolone 40 MG
- Volunteers
- 40 people
- Sponsor
- University of Manitoba
Understand the Effects of tACS on the Brain
Investigating Transcranial Alternating Current Stimulation (tACS) Preconditioning Effects on Resting and Active Motor Threshold
Previous studies have looked at the potential of using transcranial direct current stimulation (tDCS) to prime the brain in order to lower the resting motor threshold.
- Trial name
- NCT05503823
- Testing
- tACS or tRNS and TMS
- Where
- Canada
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Healthy Participants
Pilot Assessment of the Safety of a Combination of Curcumin, Omega-3, and Vitamin D Supplements
Curcumin, Omega-3 and Vitamin-D (COD) are commonly used dietary supplements, which are licensed natural health products in Canada.
- Trial name
- PASCOD (NCT05414838)
- Testing
- Curcumin, Omega-3 and Vitamin-D (COD)
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Early Childhood Caries
A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children
Silver diamine fluoride (SDF) is an antibiotic liquid that has the potential to arrest Early Childhood Caries in young children and delay treatment until children can be seen in outpatient settings.
- Trial name
- NCT04054635
- Testing
- Silver diamine fluoride
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- University of Manitoba