Clinical trials: sponsored by University of Massachusetts, Worcester
Binge Alcohol Consumption, Suicidal Ideation
Preliminary Trial of an Avatar Guided Digital Intervention for Emerging Adults
The goal of this clinical trial is to learn whether a novel digital avatar (virtual coach) support program can help emerging adults ages 18-29 who present to the emergency department with suicidal thoughts and alcohol misuse…
- Trial name
- EA-Avatar (NCT07418047)
- Testing
- EA-Avatar, Suicide safety planning app
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Massachusetts, Worcester
Binge Drinking, Suicidal Ideation
Open Pilot Trial Evaluating an Avatar-Guided Intervention for Emerging Adults With Alcohol Use Problems and Suicide Risk
This study is an open pilot usability trial to test the 1) usability of a newly developed mobile health intervention to help manage suicidal ideation and alcohol use problems and 2) feasibility of research protocols with emerging…
- Trial name
- EA-Avatar (NCT06595862)
- Testing
- EA-Avatar
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Tobacco Smoking
Adapt2Quit - An Adaptive Motivational System for Socio-Economically Disadvantaged Smokers
The goal of this research is to test the Adapt2Quit computer program that uses participant input (message rating on how much the text motivational message might influence one to quit smoking) to select and text motivational…
- Trial name
- A2Q (NCT04720625)
- Testing
- Adapt2Quit, Control
- Where
- 3 sites in United States
- Volunteers
- 757 people
- Sponsor
- University of Massachusetts, Worcester
Weight Stigma
Adapting a Health at Every Size Intervention to Obstetric Care
Perinatal mental health disorders occur in 1 in 5 pregnancies and have significant negative intergenerational consequences including being the leading cause of overall and preventable mortality during pregnancy and the first year…
- Trial name
- OB-HAES (NCT06919783)
- Testing
- Health at Every Size in Obstetrics
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Massachusetts, Worcester
Inflammatory Bowel Diseases
The Inflammatory Bowel Disease - Anti-Inflammatory Diet (IBD-AID)
The goal of this study is to prospectively test the hypothesis that specific dietary modification can improve patient symptoms by promoting beneficial changes in the composition of the microbiome that, in turn, alter the immune…
- Trial name
- IBD-AID (NCT04757181)
- Testing
- The IBD-AID
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Massachusetts, Worcester
Pediatric Delirium
Pediatric Delirium
Preventing emergent delirium in pediatric ambulatory surgery through preoperative use of intra-nasal Dexmedetomidine and oral Midazolam.
- Trial name
- NCT04669457
- Testing
- Intra-nasal Dexmedetomidine, Oral Midazolam
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Antisocial Behavior
Multisystemic Therapy-Emerging Adults Trial
This study's purpose is to test the effectiveness of a promising intervention for emerging adults (EAs) with mental illness (MI) and serious antisocial behavior in achieving the ultimate outcome of reduced antisocial behavior…
- Trial name
- MST-EA (NCT02922335)
- Testing
- Multisystemic Therapy for Emerging Adults, Enhanced Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 193 people
- Sponsor
- University of Massachusetts, Worcester
Vaccination, Vaccination Promotion
ARISe at UMass Chan
The goal is to identify the most impactful strategies for capturing attention and enhancing effectiveness of vaccine promotion messages.
- Trial name
- ARISe (NCT07236034)
- Testing
- Exposure to source and message content
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Diabetes Mellitus Type 2, Social Determinants of Health (SDOH)
Re-Engineered Discharge for Diabetes Care Transitions
The goal of this project is to test a novel bedside SDOH screening intervention coupled with post-discharge navigation for hospitalized patients with a diabetes diagnosis to reduce unmet social needs, compared to usual care.
- Conditions
- Diabetes Mellitus Type 2, Social Determinants of Health (SDOH), Hospital Readmission
- Trial name
- REDDCAT2 (NCT06869057)
- Testing
- REDDCAT2 Post-Discharge Navigation, Treatment as Usual (TAU)
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- University of Massachusetts, Worcester
Tobacco Cessation
Tobacco Cessation Texting Intervention for People Living With HIV Who Smoke in Vietnam
The intersection of smoking and HIV/AIDS poses a serious public health threat in Vietnam. Vietnam is dealing with these two challenges with parallel rather than integrated plans.
- Trial name
- M2Q2-HIV (NCT05863923)
- Testing
- mHealth Messaging to Motivate Quitline use and Quitting among Persons Living With HIV (PLWH) in Vietnam (M2Q2-HIV), M2Q2-HIV Comparison
- Where
- 2 sites in United States, Vietnam
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Influenza, COVID-19
Patient-Centered Practical Vaccine Talk For Busy Clinicians
The goal of this study is to assess the effect of an educational intervention for primary care providers (PCPs) on influenza and COVID-19 vaccine uptake among their adult patients through a pragmatic, cluster randomized trial in…
- Trial name
- PCP-VAX (NCT07651761)
- Testing
- Provider communication training
- Where
- United States
- Volunteers
- 24,500 people
- Sponsor
- University of Massachusetts, Worcester
Suicide Risk
Telehealth to Improve Prevention of Suicide (TIPS)
The study will rigorously evaluate whether synchronous, within-visit telemental health evaluation and intervention services can successfully overcome poor access to behavioral health and substandard suicide-related care in…
- Trial name
- TIPS (NCT04800029)
- Testing
- TIPS Program, TIPS Program + ED-SAFE
- Where
- United States
- Volunteers
- 32,406 people
- Sponsor
- University of Massachusetts, Worcester
Hypertension in Pregnancy, Chronic Hypertension
Moms@Home: A Storytelling-based Mobile Health Intervention to Improve Blood Pressure Management in Pregnancy
This pilot study will examine the effects of a digital health approach, Moms@Home, on home blood pressure monitoring in a diverse population of pregnant women with hypertension.
- Conditions
- Hypertension in Pregnancy, Chronic Hypertension, Gestational Hypertension
- Trial name
- Moms@Home (NCT06835959)
- Testing
- Moms@Home, Enhanced Standard of Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Massachusetts, Worcester
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Depression, Economic Vulnerability
ASHA Bangladesh--An Integrated Intervention to Address Poverty and Depression
The goal of this randomized controlled trial is to compare the impact of an integrated intervention combining poverty alleviation and depression treatment to depression treatment alone, in low income rural Bangladeshi women with…
- Conditions
- Depression, Economic Vulnerability, Anxiety, Culture Specific Symptoms
- Trial name
- NCT06295250
- Testing
- Manualized Group Based Psychotherapy, Poverty Alleviation
- Where
- Bangladesh
- Volunteers
- 600 people
- Sponsor
- University of Massachusetts, Worcester
COPD, Early-Onset
SPIROMICS Study of Early COPD Progression (SOURCE)
This is an observational study of 1000 participants to further define the nature of early chronic obstructive pulmonary disease (COPD) in younger, at-risk individuals.
- Trial name
- SOURCE (NCT05033990)
- Where
- 14 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Preterm Birth
The Social Determinants of Health Screening and Referral Project
Up to a quarter of the families with preterm infants have unmet social needs, such as housing or job insecurity, which represent adverse social determinants of health (SDOH).
- Trial name
- NCT06582147
- Testing
- Implementation of social determinants of health screening and referral
- Where
- 7 sites in United States
- Volunteers
- 882 people
- Sponsor
- University of Massachusetts, Worcester
Hyperlipidemias, Diabetes
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful…
- Conditions
- Hyperlipidemias, Diabetes, Depression, Pediatric Asthma
- Trial name
- NCT06903897
- Testing
- WE CARE SDOH System, Standard Pediatric Care
- Where
- 3 sites in United States
- Volunteers
- 68,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Schizophrenia, Schizo Affective Disorder
Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia
The main question this study is trying to answer is whether lumateperone, an FDA-approved antipsychotic drug, can help reduce possible side effects of clozapine, such as weight gain and elevated levels of sugar and bad…
- Trial name
- NCT06174116
- Testing
- Lumateperone
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Massachusetts, Worcester
Safe Sleep Education, SUID
Social Media and Risk-reduction Training for Preterm Infant Care Practices
SMART Preemie is a cluster randomized trial that will investigate the effectiveness of NICU-based and post-discharge interventions to improve adherence to safe sleep practices among mothers of preterm infants.
- Conditions
- Safe Sleep Education, SUID, Sudden Infant Death Syndrome (SIDS)
- Trial name
- SMART Preemie (NCT07420686)
- Testing
- Safe Sleep NICU Quality Improvement Campaign, Shared Reading NICU Quality Improvement Campaign, Safe Sleep TodaysNICUBaby videos and messages
- Where
- United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester