Clinical trials: open to volunteers, sponsored by University of Michigan
Parkinson Disease
A Pilot Study of In-lab Dynamic Standing in Parkinson's Disease
This research is studying the use of a new type of standing desk in a small number of people to learn about the user experience for people with Parkinson's disease.
- Trial name
- FOGSTAND (NCT07543861)
- Testing
- Dynamic Standing Desk
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Michigan
Postpartum Depression (PPD)
Informing Implementation of a Circadian-Focused Intervention for Postpartum Depression
The proposed study is an open-label trial of Re-Timer® wearable morning bright light therapy for postpartum depression. The study is focused on evaluating the feasibility, acceptability, and implementation context of morning…
- Trial name
- NCT07766161
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Gum Disease
Influence of Implant Crown Transmucosal Contour Design on Soft and Hard Tissue Clinical Outcomes
This study will evaluate how the crown's shape under the gums will influence the gum tissue around dental implants.
- Trial name
- NCT06185075
- Testing
- Implant crown delivery
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healthy, Covert Consciousness
Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study
This research is studying whether mental functions take place during different levels of anesthesia, using a commonly used drug (either dexmedetomidine [with propofol in some participants] or ketamine), which shows areas in the…
- Trial name
- NCT07705022
- Testing
- Dexmedetomidine (+propofol as indicated), Ketamine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Depression
Intern Health Study
Retrospective studies have established a strong correlation between reports of life stress and depression. Investigators have begun to further explore this relationship by examining the role of gene x stress interactions in the…
- Trial name
- NCT01809080
- Where
- United States
- Volunteers
- 25,000 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Epilepsy
Outcomes After Planned Discontinuation of AntiSeizure Medication
The main purpose of this study is to understand the effects of continuing versus discontinuing antiseizure medications after a period of seizure-freedom.
- Trial name
- STOP-ASM (NCT07750496)
- Testing
- Discontinue antiseizure medications
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Perimenopause
Hemodynamics After Resistance Training
Women's blood vessel health gets worse after menopause, or "the change of life". Some women exercise less during menopause. Exercise can improve blood vessel health.
- Trial name
- HeART (NCT07022340)
- Testing
- Resistance Training Intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Physical Inactivity, Aging
Motivating Activity Through Text Communications - Helping Adults Increase Movement
The goal of this clinical trial is to compare the effect of different types of text messages on physical activity levels of middle-aged and older adults and to determine whether these messages are effective in adults age 40 and…
- Conditions
- Physical Inactivity, Aging, Cognitive Ability, Behavior Change
- Trial name
- MATCH AIM (NCT07593677)
- Testing
- Text Messaging Intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Horizontal Ridge Deficiency
Implant Phenotype Modification Via GBR and ADM
Single implant sites with bone loss can often be managed by bone grafting alone. The purpose of this study is to determine whether putting a soft tissue graft substitute over the bone graft will provide an increased benefit for…
- Trial name
- NCT07082244
- Testing
- Dental implant placement, Guided bone regeneration with collagen membrane, Guided bone regeneration with acellular dermal matrix.
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Pediatric Surgical Procedures
Adolescent Surgery Roadmap Feasibility and Acceptability Study
The goal of this clinical trial is to test the feasibility and acceptability of using a mobile health app, Ane-Roadmap, designed to support adolescents (ages 12-17) undergoing painful surgeries and their caregivers.
- Trial name
- Ane-Roadmap (NCT06991673)
- Testing
- Behavioral Treatment
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Kidney Injury, Acute
Inorganic Nitrate (NaNO3) Prevention of Contrast-Associated Acute Kidney Injury
This pilot study is designed to test the logistics and recruitment of a trial testing the benefit of sodium nitrate in the prevention of contrast-associated kidney injury in a group of patients at high-risk.
- Trial name
- NCT07016074
- Testing
- Sodium Nitrate
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Michigan
Blood Loss, Surgical, Blood Loss, Postoperative
Prophylactic Intravenous Calcium Gluconate to Decrease Blood Loss at Time of Cesarean Delivery in Pregnant Patients at High Risk for Uterine Atony
This research study is being done to learn what effect a single dose of calcium gluconate will have on blood loss at the time of cesarean delivery in pregnancy patients at high risk for uterine atony.
- Conditions
- Blood Loss, Surgical, Blood Loss, Postoperative, Uterine Atony
- Trial name
- NCT07217899
- Testing
- Calcium Gluconate, Saline
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Inflammatory Bowel Diseases
Virtual Reality (VR) -Directed Brain Gut Behavioral Treatment (BGBT) for Inflammatory Bowel Disease (IBD) Inpatients
The research is studying virtual reality (VR)-directed brain-gut behavioral therapy (BGBT) as a pain treatment option for hospitalized patients with inflammatory bowel disease (IBD).
- Trial name
- NCT06188793
- Testing
- Virtual reality-directed BGBT
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Inflammatory Bowel Diseases, Ulcerative Colitis
Developing a Self-Management Intervention to Improve Health Outcomes for Patients With Inflammatory Bowel Disease
This research is studying whether changing an individual's behaviors may have an impact as a treatment or outcome for inflammatory bowel disease.
- Conditions
- Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
- Trial name
- NCT07456566
- Testing
- Digital self-management program, Standard Care
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Opioid Use Disorder, Healthy
Adversity, Brain and Opioid Use Study
The way people process and remember information may be related to adverse childhood experiences and Opioid Use Disorder symptoms.
- Trial name
- NCT06355778
- Testing
- Magnetic Resonance Imaging (MRI), Computer Tasks
- Where
- United States
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Suicidal, Suicide, Attempted
Improving Coping to Reduce Suicide Risk Following ED Discharge
The researchers hope to learn whether an electronic safety plan (ESP) and a supportive text messaging program are feasible and acceptable to adult patients with recent suicidal thoughts or behavior after emergency department (ED)…
- Conditions
- Suicidal, Suicide, Attempted, Suicidal Ideation
- Trial name
- NCT06614946
- Testing
- Electronic Safety Plan (ESP), Text support
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Health Promotion, Cardiovascular Health
Health Impact 360: Advancing Physical, Social, and Mental Health Toward Cardiovascular Disease Prevention in Community Settings
The purpose of this clinical trial is to evaluate an evidence-based intervention, Health Impact 360, toward the promotion of cardiovascular health (CVH), including physical, mental, and social health outcomes, among adults living…
- Trial name
- HI360 (NCT07034352)
- Testing
- Health Impact 360, Usual care - Wait list control
- Where
- 7 sites in United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Healing Wound
Effect of Age on PRF Quality; Assessed by Evaluating Healing Outcomes of ARP
This study will examine whether using PRF and your age are going to affect the healing and regeneration benefits gained from PRF.
- Trial name
- NCT07023757
- Testing
- Socket preservation
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Obesity
Identification of Phenotypic Factors That Predict Success for Weight Loss and Long-term Weight Maintenance
The Investigational Weight Management Clinic now entitled the Weight Management Program at the University of Michigan was created to identify strategies that will result in cost-effective, long term weight management for…
- Trial name
- NCT02043457
- Testing
- phenotyping
- Where
- United States
- Volunteers
- 3,200 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Clostridioides Difficile Infection
Lifestyle and Recurrent Clostridioides Difficile Infection (CDI)
This study aims to evaluate the impact of diet on the gut microbiome in adults with Clostridioides difficile infection (CDI). Eligible participants will be randomized and receive meals plus different types of health counseling.
- Trial name
- NCT07613645
- Testing
- Health counseling sessions, Diet (control diet), Diet (experimental diet)
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Michigan