Clinical trials: completed, sponsored by University of Michigan
Hirschsprung Disease
Probiotic Prophylaxis of Hirschprung's Disease Associated Enterocolitis (HAEC)
Prospective, randomized, controlled trial to test if post-operative administration of probiotics in HD patients will lead to a reduction in the occurrence of HAEC.
- Trial name
- NCT00630838
- Testing
- VSL#3
- Where
- 2 sites in United States
- Volunteers
- 62 people
- Sponsor
- University of Michigan
End Stage Renal Failure
Volume,Sodium and Blood Pressure Management in HD
The purpose of this study to conduct a pilot, randomized trial in stable HD patients to evaluate the effect of gradual, step-wise reduction of post-hemodialysis target weight, combined with diligent dietary sodium restriction and…
- Trial name
- VSBP (NCT01766882)
- Testing
- Lower sodium intervention, Progressive Challenge to Post Dialysis Weight
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
Childhood Obesity
Active Class Space Metabolic Benefits Study
ACS examined the potential influence of intermittent physical activity breaks of various intensities (control, light, moderate, vigorous) on measures of immediate mental performance, mood, hunger and several metabolic outcomes in…
- Trial name
- ACS (NCT02831309)
- Testing
- Light-Intensity Condition, Moderate-Intensity Condition, High-Intensity Condition
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Food Allergy
Quality of Life in Food Allergic Families
Food allergies are becoming more prevalent with more children being diagnosed with food allergies each year. Food allergies place a tremendous burden not just on the patient but on his/her family as well.
- Trial name
- NCT01054950
- Testing
- Counseling
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Asthma
Breathing Exercises for Asthma
Despite the advances in pharmacological therapy for asthma, there has been an increasing worldwide interest in alternative therapies for asthma.
- Trial name
- NCT02151422
- Testing
- Breathing exercise
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Breast Cancer, Arthralgia
Loss of Grip Strength, BMI, and Adjuvant Endocrine Therapy Breast Cancer
Early stage hormone receptor positive breast cancer is typically treated with adjuvant endocrine therapy in order to decrease risk of breast cancer recurrence and to improve overall survival from the disease.
- Conditions
- Breast Cancer, Arthralgia, Obesity
- Trial name
- LOGRIBMET (NCT01896050)
- Testing
- anastrozole, letrozole, exemestane, Tamoxifen
- Where
- United States
- Volunteers
- 115 people
- Sponsor
- University of Michigan Rogel Cancer Center
Sleep, Pain
Sleep Enhancing Tools: Pilot Study
To demonstrate whether use of sleep enhancing aids (face mask, ear plugs or white noise machine) in hospitalized patients can positively affect subjective symptoms of sleep quality, fatigue and pain.
- Trial name
- NCT02068703
- Testing
- Sleep Education Presentation, Sleep Tool Demonstration
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Michigan
Endocrine and Metabolic Responses to Exercise and Diets
Exercise Effects on Insulin, Gut Peptides, and Appetite
Determine whether the mid-day suppression of hunger and amplified increase in the release of glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide 1 (GLP-1) following morning exercise is due to increased fat…
- Trial name
- XFG (NCT01891617)
- Testing
- Exercise and diets
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Asthma
Women of Color and Asthma Control
The proposed randomized controlled trial will evaluate an innovative intervention in 420 African American women with asthma. It will be the first to use a highly tailored, telephone counseling approach to address both specific…
- Trial name
- NCT01117805
- Testing
- Telephone counseling intervention
- Where
- United States
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- University of Michigan
African American Infant Sleep Beliefs and Practices
Improving the Self-Efficacy of African American Parents in Infant Supine Sleep
This is a research study of African American parents/caregivers of newborns. The purpose of this research study is to learn what type of educational materials about infant safety and safe infant sleep are most effective and…
- Trial name
- PrAAIS (NCT01707173)
- Testing
- Tailored education, Standard Education
- Where
- United States
- Volunteers
- 735 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Diabetes Mellitus
REACH Detroit Partnership Family Intervention
The objectives of the proposed study are to determine whether culturally diverse community residents with diabetes are willing to participate in our community health worker intervention using randomized controlled trial (RCT)…
- Trial name
- NCT00800410
- Testing
- Community Health Worker (CHW) services
- Where
- United States
- Volunteers
- 183 people
- Sponsor
- University of Michigan
Kidney Transplant Recipient, Heart Transplant Recipient
Pharmacokinetics of Mmf and Valganciclovir
The primary objective of this study is to determine whether a clinically significant PK drug interaction ( a 30% difference in the AUC of MPA) exists between mycophenolate mofetil (under steady state conditions) and VGCV in renal…
- Trial name
- NCT00189150
- Testing
- Mycophenolate mofetil, Valganciclovir
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Thrombosis
Ultrasound Elasticity Imaging of Venous Thrombi
The purpose of this study is to see if the investigators can use ultrasound imaging to determine the type of clots in patients to help better manage their care.
- Trial name
- NCT00726947
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 254 people
- Sponsor
- University of Michigan
Pregnancy, Weight Gain
Effectiveness of Video Messaging About Diet, Exercise and Weight Gain in Pregnancy in Regional and National Samples
The primary purpose of this study is to assess the responses of pregnant women and their social network to six videos about health in pregnancy.
- Trial name
- NCT02490579
- Testing
- Responses to Brief Video Messages (Facebook), Response to Brief Video Messages (Clinic), Response to Brief Video Messages (Social Network)
- Where
- United States
- Volunteers
- 1,670 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Bladder Cancer
Study of Gemcitabine and Cisplatin With or Without Cetuximab in Urothelial Cancer
This study will compare the effects, good and/or bad, of chemotherapy (Gemcitabine and Cisplatin) with or without the addition of the chemotherapy drug Cetuximab to find out which treatment is better.
- Trial name
- NCT00645593
- Testing
- Gemcitabine,, Cisplatin, Cetuximab
- Where
- 14 sites in United States
- Volunteers
- 89 people
- Sponsor
- University of Michigan Rogel Cancer Center
Systemic Lupus Erythematosus
Dehydroepiandrosterone (DHEA) in Systemic Lupus Erythematosus (SLE) for Coronary Artery Disease (CAD) Prevention
The purpose of this study is to evaluate the effect of DHEA on endothelial dysfunction in patients with systemic lupus by measuring: 1. changes in brachial artery flow-mediated dilatation (FMD) and 2.
- Trial name
- NCT00189124
- Testing
- Dehydroepiandrosterone (DHEA)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Michigan
Non-Hodgkin's Lymphoma
Imaging Based Dosimetry for Individualized Internal Emitter Therapy
The goal of this study is to develop imaging based methods to accurately determine the energy absorbed (absorbed dose) by tumor tissue and bone marrow after radioimmunotherapy with I-131 tositumomab .
- Trial name
- NCT01988272
- Testing
- SPECT/CT imaging
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Michigan
ALS, Amyotrophic Lateral Sclerosis
Cortex Changes in Real/Imagined Movements in Amyotrophic Lateral Sclerosis (ALS)
The purpose of this study is to track areas of the brain, via functional magnetic resonance imaging (fMRI), that retain structural and functional integrity throughout the lifespan of people with amyotrophic lateral sclerosis…
- Trial name
- NCT00809224
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Urinary Incontinence
Translating Unique Learning for Incontinence Prevention
More than one in three US women suffers from the distressing, embarrassing, and often unreported problem of urinary incontinence (UI). UI severity increases with age and the financial cost exceeds $19 billion per year .
- Trial name
- TULIP (NCT01599715)
- Testing
- Instructional DVD, Bladder Health Class
- Where
- 2 sites in United States
- Volunteers
- 647 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Chronic Obstructive Pulmonary Disease (COPD)
Developing a COPD Case Finding Methodology for Primary Care
The purpose of this qualitative work is to inform the content and structure of a new screening measure for identifying undiagnosed at-risk COPD cases in primary care and support content validity of the measure.
- Trial name
- NCT01880177
- Where
- 4 sites in United States
- Volunteers
- 346 people, healthy volunteers welcome
- Sponsor
- University of Michigan