Clinical trials: sponsored by University of Michigan
Bipolar Disorder, Schizo Affective Disorder
Brain Stimulation and Cognitive Training
People with serious mental illness often report difficulties with thinking skills like memory. These difficulties can make it harder to perform day-to-day activities.
- Conditions
- Bipolar Disorder, Schizo Affective Disorder, Schizophrenia
- Trial name
- NCT03338673
- Testing
- tDCS, BrainHQ
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Sedentary Behavior
Active for Life Assisted Living Feasibility and Acceptability Study
This study examines the effects of a physical activity and behavioral program, called Active for Life, to promote increased physical activity and reduced sedentary behavior of older adults who live in assisted living.
- Trial name
- NCT04386434
- Testing
- Active for Life: Assisted Living
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Michigan
Esophageal Cancer
Routine Post-Operative Supplemental Nutrition
Patients undergoing an esophagectomy will be randomized to receive either (1) routine post-operative tube feeding for 1 month post-operative or (2) usual practice, which is tube feeding to continue in the hospital until the…
- Trial name
- NCT02297607
- Testing
- Tube Feeding
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Michigan
Healthy
Neuroimaging of Anesthetic Modulation of Human Consciousness
This study's purpose is to see if mental functions take place during different levels of anesthesia, using a commonly used drug (Propofol).
- Trial name
- NCT03361605
- Testing
- Propofol
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Opioid-Related Disorders
The OPT-IN Project
Prescription opioid overdose represents a public health crisis. A number of efforts have been implemented to address opioid prescribing and opioid risk mitigation strategies for prescribers, but relatively few efforts have sought…
- Trial name
- NCT03526380
- Testing
- Behavioral: the OPT-IN Intervention
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- University of Michigan
Pain
Mechanistic Study of Duloxetine in Breast Cancer Patients With Chronic Pain
Early stage breast cancer is typically treated with surgery, chemotherapy, radiation therapy, and/or endocrine therapy. Following treatment, 25-60% of breast cancer survivors have reported chronic pain, which can be difficult to…
- Trial name
- NCT01912612
- Testing
- Duloxetine
- Where
- 2 sites in United States
- Volunteers
- 82 people
- Sponsor
- University of Michigan Rogel Cancer Center
Fibromyalgia
Developing Biomarkers for Fibromyalgia
The hypothesis of this study is that biological markers are present in the body that are good indicators of chronic pain. Eligible participants will be assessed at baseline and after receiving a series of acupuncture or "sham"…
- Trial name
- Biomarkers (NCT00932061)
- Testing
- Traditional Acupuncture
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Prostate Cancer
Abemaciclib With or Without Atezolizumab in Metastatic Castration Resistant Prostate Cancer
This research is studying two experimental drugs, abemaciclib and atezolizumab, alone and in combination with each other, to learn about the safety and effectiveness of these treatments and their side effects.
- Trial name
- NCT04272645
- Testing
- Abemaciclib 200 MG, Atezolizumab 1200 MG in 20 ML Injection, Abemaciclib 150 MG
- Where
- 4 sites in United States
- Sponsor
- University of Michigan Rogel Cancer Center
Hypertension
Utilizing Consumer Health Informatics to Support Management of Hypertension by Clinical Pharmacists in Primary Care
The purpose of this research study is to test the feasibility, acceptability, and preliminary effectiveness of the use of a mobile pharmacist-led intervention that incorporates home BP monitoring and medication reminders with…
- Trial name
- NCT02898584
- Testing
- BP Track
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Michigan
Ovarian Cancer Risk, Risk-reducing Surgery
Why do Oral Contraceptives Prevent Ovarian Cancer?
Use of oral contraceptives (OCs) reduces a woman's risk of ovarian cancer very significantly and the protective effect continues for at least 25 years after use of OCs is stopped; the mechanisms of how this occurs are not…
- Conditions
- Ovarian Cancer Risk, Risk-reducing Surgery, Fallopian Tube Fimbriae, Ovarian Cortical Inclusion Cysts
- Trial name
- NCT02155777
- Testing
- OrthoNovum 1/35
- Where
- 3 sites in United States, Canada
- Volunteers
- 52 people
- Sponsor
- University of Michigan
Mantle Cell Lymphoma
Bortezomib in Combination With Ibrutinib in Ibrutinib Relapsed Mantle Cell Lymphoma
This is a phase II study to evaluate the efficacy of ibrutinib in combination with bortezomib in in MCL (mantle cell lymphoma) patients who relapsed on single agent ibrutinib.
- Trial name
- NCT03617484
- Testing
- Bortezomib, Ibrutinib
- Where
- United States
- Sponsor
- University of Michigan Rogel Cancer Center
Diet, Healthy
Warning Labels and College Students' Sugar-Sweetened Beverage Intake
Sugar-sweetened beverages (SSBs) are one of the few dietary items causally linked to the development of obesity and chronic disease.
- Trial name
- NCT04435145
- Testing
- Sugar-sweetened beverage warning label
- Where
- United States
- Volunteers
- 1,067 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Heart Failure
Self-Management App for Patients With Left-Ventricular Assist Devices
The purpose of this study is to evaluate the use of VAD Care App in an out-patient mechanical circulatory support program. The specific aim for this pilot study is to obtain preliminary efficacy data of the VAD Care App as a…
- Trial name
- NCT03049748
- Testing
- Mobile phone app (VAD Care App), Usual LVAD Care
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Michigan
Liver Fibroses
Increased Liver Stiffness: A Study of Acoustic Radiation Force Impulse (ARFI) Elastography
The goal of this study is to determine if ultrasound tools can be used to detect liver stiffness. Acoustic radiation force impulse (ARFI) elastography and backscatter will be used to see if they can detect liver stiffness in…
- Trial name
- NCT03382119
- Testing
- Ultrasound with ARFI (acoustic radiation force impulse), Ultrasound with backscatter imaging
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Michigan
Hypothyroidism; Surgery, Head and Neck Cancer
Wound Complications in Head and Neck Surgery
This is a prospective observational study evaluating wound complications following head and neck surgery. Patients undergoing major head and neck surgery will be included in the study.
- Conditions
- Hypothyroidism; Surgery, Head and Neck Cancer, Wound Heal, Laryngeal Cancer
- Trial name
- NCT03134976
- Testing
- Levothyroxine
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of Michigan
Breast Cysts, Breast Tumors
Simulated Screening Study for Breast Imaging
This is a pilot, simulated breast cancer screening study. The goal of the study is to explore these scanning modalities: 1) Combined digital breast tomosynthesis(DBT)/dual-sides 3 dimensional-automated ultrasound(AUS) 2.
- Trial name
- NCT01807754
- Testing
- X-ray and ultrasound imaging scanning, Photoacoustic imaging scans for breast cancer screening
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Michigan
High Utilization of Emergency Departments
An Evaluation of the Michigan State Innovation Model in Washtenaw and Livingston Counties
This study will examine the effects of a care management program on the health and health spending outcomes of patients residing in Michigan's Washtenaw and Livingston Counties.
- Trial name
- NCT03293160
- Testing
- Care management services
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Michigan
Hepatic Irradiation
Assessment Of Liver Function in Patients Undergoing Hepatic Irradiation
The goal of the trial is to assess the effect of radiation treatment on liver function as determined by indocyanine green extraction.
- Trial name
- IC-Green (NCT01519219)
- Testing
- Hepatic Irradiation
- Where
- United States
- Volunteers
- 208 people
- Sponsor
- University of Michigan Rogel Cancer Center
Brain Tumors
Evaluation of Human Brain Tumor Therapy Response by Magnetic Resonance (MR)
The purpose of this study is to determine if new MRI methods that measure various information and chemical makeup in the brain, will give early information regarding response to treatment in patients with brain tumors.
- Trial name
- NCT00724191
- Testing
- MRI
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- University of Michigan
Depression
Happy@Home: Delivering iCBT With Homecare Workers to At-Home Seniors
Depression is one of the most common and debilitating conditions among older adults. At-home seniors, also called homebound seniors, are older adults who are confined to a bed or chair and are unable to get about outdoors.
- Trial name
- Happy@Home (NCT04267289)
- Testing
- Beating the Blues
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Michigan