Clinical trials: sponsored by University of Minnesota
Tobacco Use
Sugars in Cigarettes
The aim of this study is to investigate the impact of sugar levels in cigarette tobacco on cigarette abuse liability and appeal.
- Trial name
- NCT05308316
- Testing
- Cigarettes with added sucrose
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Congenital Heart Disease
RAPID: a Comparison Study of a Novel Ultrasound Device of Automated Congenital Heart Imaging
The RAPID ultrasound is a portable imaging device that captures a one point image from the subcostal region of the heart. The device is set on the patient's chest and captures the image in \<1 minute.
- Trial name
- NCT06281639
- Testing
- RAPID
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Minnesota
TBI (Traumatic Brain Injury)
Depth Electrode Detection of Cortical Spreading Depolarization After Traumatic Brain Injury
Preliminary evaluation of depth electrode recording and novel algorithms to determine Cortical Spreading Depolarization's (CSD) following traumatic brain injury (TBI) requiring neurosurgical intervention.
- Trial name
- NCT05205174
- Testing
- depth electrodes
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Minnesota
Cystic Fibrosis
The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development
While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the relative abundance of bacterial taxa at…
- Trial name
- NCT03016689
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Minnesota
Hearing Loss
A System and Process to Improve the Satisfaction With Hearing Health Products
Innovative Design Labs Inc. (IDL) and its collaborators, proposes to create a cloud-based system which integrates advances and techniques from Health and Wellness Coaching (HWC) into the Hearing Aid (HA) fitting and trial process.
- Trial name
- NCT04926636
- Testing
- Health and Wellness Coaching
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Minnesota
Smoking, Tobacco Use
The Effect of Tobacco Products on Wound Healing
The purpose of this study is to evaluate the effect of various tobacco products (including but not limited to combustible cigarettes, medicinal nicotine, electronic cigarettes, and smokeless tobacco) on cutaneous wound healing.
- Conditions
- Smoking, Tobacco Use, Tobacco Smoking
- Trial name
- NCT04870970
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Gaucher Disease Type 1
Role of Oxidative Stress and Inflammation in Type 1 Gaucher Disease (GD1)
The purpose of this study is to measure levels of blood and brain chemicals related to oxidative stress and inflammation in healthy volunteers and individuals with Type 1 Gaucher disease (GD1) to see if these levels are altered…
- Trial name
- NCT02583672
- Testing
- N-acetylcysteine
- Where
- 2 sites in United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Rib Fractures
Cryo Rib Fracture Study
The purpose of this study is to determine if patients with rib fractures who undergo cryoablation of the intercostal nerves have improved pain control 7 days from procedure when compared to those who have a ESP catheter.
- Trial name
- NCT06347874
- Testing
- Cryoablation, ESP Catheter
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Minnesota
Cognition, Healthy Participants
Cognitive Strategies in Early Psychosis 1
The goal of this clinical is to learn more about decision making in psychosis spectrum disorders, like schizophrenia. The investigators will ask people who do not have psychosis to take a single dose of modafinil and then…
- Trial name
- COSTEP 1 (NCT07231497)
- Testing
- Modafinil
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smokers, Vaping
Persistence of Oral DNA Adducts in Smokers and Vapers
This study aims to better understand what damage caused to oral cells from smoking and vaping might be important in the formation of oral cancers.
- Conditions
- Smokers, Vaping, Healthy Volunteers
- Trial name
- NCT06983392
- Testing
- Abstain from smoking/vaping
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Treatment Resistant Depression
Enhanced Spatial Targeting in ECT Utilizing FEAST
The purpose of this research study is to find an alternative version of ECT that reduces the negative side effects (mainly memory loss) while still providing patients with relief from depressive symptoms.
- Trial name
- NCT04099342
- Testing
- FEAST, FEAST RP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
HTN
mGlide-Care: A Partnership With Caregivers
Hypertension (HTN) is the most significant stroke, cardiovascular disease and dementia risk factor and is substantially under-treated especially in older persons.
- Trial name
- NCT05850416
- Testing
- mGlide-Care, Usual Care +
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Minnesota
Opioid Use Disorder, Anxiety
Autonomous Digital CBT Intervention for Opioid Use Disorder in Individuals With Co-Occurring Internalizing Disorders
The primary objective of this protocol is to implement the UG3 phase (Phase 1) of a National Institute on Drug Abuse (NIDA) UG3/UH3 grant (RFA-DA-23-049).
- Conditions
- Opioid Use Disorder, Anxiety, Depression
- Trial name
- NCT06545071
- Testing
- NEAT-O program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Minnesota
Colorectal Cancer
Colorectal Cancer Legal and Administrative Burden Support: A Pilot Clinical Trial
This is a single center single-arm, pilot study of proactive and early connection with free legal care services for persons with advanced colorectal cancer to assess the feasibility, acceptability, and preliminary efficacy of…
- Trial name
- NCT06475664
- Testing
- Personalized legal care services
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Minnesota
Covid19, SARS-CoV Infection
Direct Topical Lung T3 Treatment to Improve Outcome & Sequelae of COVID-19 Acute Respiratory Distress Syndrome
Acute treatment of COVID-ARDS with direct topical lung instilled T3 therapy for patients on mechanical ventilation.
- Conditions
- Covid19, SARS-CoV Infection, ARDS, ARDS, Human
- Trial name
- NCT04725110
- Testing
- Instilled T3
- Where
- United States
- Sponsor
- University of Minnesota
Major Depressive Disorder
Feasibility Pilot of Accelerated Stimulation With TMS for Treatment of Major Depressive Disorder (FAST-MDD)
This is a mixed-methods study that includes three steps. The first is a focus group to collect opinions and feedback about implementation of aTMS among clinicians, technicians, nurses, and other clinical staff at the St.
- Trial name
- NCT06961851
- Testing
- aTMS utilizing the MagVenture TMS device
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Behavior Problem, Behavior, Child
Effectiveness of an Online Parenting Training
Child and adolescent behavioral health problems are related to the leading causes of youth morbidity and mortality. Parent-focused preventive interventions, such as GenerationPMTO (GenPMTO), effectively prevent behavioral health…
- Conditions
- Behavior Problem, Behavior, Child, Parents, Parent-Child Relations
- Trial name
- NCT05111886
- Testing
- Communication Skills Training, eHealth GenPMTO, Written Referral Process
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Type 2 Diabetes
Collaborative Solutions for Breaking up Sedentary Time in Black Older Adults With Type 2 Diabetes: The Interrupt Diabetes Study
The disparate burden of Type 2 Diabetes (T2D) faced by Black individuals makes attention to preventing or delaying the development of T2D and its associated cardiovascular (CV) complications, essential.
- Trial name
- NCT06283849
- Testing
- strategies to break up SB
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
Duodenal Neoplasm, Pancreatic Neoplasm
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
This phase II trial compares the effect of rectus sheath block with liposomal bupivacaine to thoracic epidural analgesia (TEA) on pain control in patients following surgical removal of all or part of the pancreas and duodenectomy…
- Trial name
- NCT06411795
- Testing
- Bupivacaine, Hydromorphone, Iopamidol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Solid Tumor, Adult, Cytotoxicity
Probiotic Supplementation During Cytotoxic Chemotherapy for Solid Tumor Malignancies
This is a pilot single-blind placebo-controlled randomized trial to establish experimental feasibility. We plan on enrolling a pilot cohort of 40 patients, with up to 5 patients in treatment phase 0 and the remaining in treatment…
- Trial name
- NCT06772090
- Testing
- Lactobacillus and Bifidobacterium
- Volunteers
- 40 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
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