Clinical trials: sponsored by University of Minnesota
No Disease State or Condition
Nutritional Language Model
Colorectal cancer survivors often face unique nutritional challenges and require support in their recovery and long0term health.
- Trial name
- NLM (NCT06661590)
- Testing
- Nutritional Messaging
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Dysbiosis, Sarcopenia
Bacterial Intestinal Gut Modification Around Cancer Surgery (BIG MACS) Diet
The long-term study objective is to develop optimized nutritional therapies for surgery and test them in clinical practice. This pilot study will test a microbiome-optimization diet in colorectal cancer surgery patients.
- Conditions
- Dysbiosis, Sarcopenia, Colon Cancer
- Trial name
- NCT05658263
- Testing
- Standard Diet, BIG MACS Diet
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Minnesota
Tobacco Use
Telehealth-Filter Ventilation ( COMET2P1 )
The goals of this project are to determine the effects of varying degrees of cigarette filter ventilation on biomarkers of toxicant exposure and smoking behavior and on subjective responses to the cigarette.
- Trial name
- NCT04969783
- Testing
- Ventilated Cigarette Filter, Unventilated Cigarette Filter
- Where
- 2 sites in United States
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Dyskeratosis Congenita, Aplastic Anemia
Hematopoietic Stem Cell Transplant for Dyskeratosis Congenita or Severe Aplastic Anemia
Fludarabine-based preparative regimen followed by an allogeneic hematopoietic stem cell transplant using related or unrelated donor in persons 0-70 years of age diagnosed with dyskeratosis congenita or severe aplastic anemia who…
- Trial name
- NCT02162420
- Testing
- Alemtuzumab, Fludarabine, Cyclophosphamide
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Spasmodic Dysphonia
Laryngeal Vibration for Spasmodic Dysphonia
The general aim of the research is to provide scientific evidence that vibro-tactile stimulation (VTS) represents a non-invasive form of neuromodulation that can induce measurable improvements in the speech of people with…
- Trial name
- SD-VTS (NCT03746509)
- Testing
- Laryngeal Vibration (Treatment), Laryngeal Vibration (Comparator)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Type 2 Diabetes
Treatment Burden Screening Questionnaire Pilot Study
The main objective of this study is to develop and evaluate a clinic-based pilot intervention to optimize patient-centered diabetes care for low income patients at risk for low quality diabetes care and poor outcomes.
- Trial name
- TBQ (NCT05870202)
- Testing
- screening tool
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- University of Minnesota
Frontal Fibrosing Alopecia
Platelet Rich Plasma for Frontal Fibrosing Alopecia
The primary objective of this study is to assess the efficacy and safety of platelet rich plasma in reducing scalp symptoms and promoting hair growth in patients diagnosed with frontal fibrosing alopecia.
- Trial name
- NCT03335228
- Testing
- Eclipse Easy Spin for PRP
- Where
- United States
- Sponsor
- University of Minnesota
Preterm Birth, Pain
Effects of Music Based Intervention (MBI) on Pain Response and Neurodevelopment in Preterm Infants
Pilot prospective randomized, double blinded, controlled study to test effect of music based intervention (MBI) on pain response and neurodevelopment in preterm infants.
- Trial name
- NCT04286269
- Testing
- Music Based Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tinnitus
Assessment of Bimodal Stimulation Device Compliance and Satisfaction in Individuals With Tinnitus
The research objective of the proposed usability study is to assess the compliance and acceptance/satisfaction of using a bimodal stimulation device with the ability to self-adjust the sound stimulus presented to the ears via…
- Trial name
- NCT05518682
- Testing
- Lenire bimodal stimulation device
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Minnesota
Tobacco Use, Tobacco Use Disorder
QuitGuide for American Indians: Aims 2 & 3
Aim 3: To test feasibility, acceptability, and preliminary efficacy of the tailored QuitGuide for smoking cessation among AIs.
- Trial name
- NCT05447156
- Testing
- Tailored QuitGuide app, Standard QuitGuide app
- Where
- United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Tobacco Use
Remote Trial - Tobacco Product Standard (VLNC)
The goal of this pilot project is to explore the feasibility of a real-world marketplace study design examining the effects of a reduced nicotine product standard for cigarettes on smoking in the context of a flavor restriction…
- Trial name
- NCT06442384
- Testing
- Tobacco and non-tobacco e-cigarettes, Tobacco only e-cigarettes
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Masonic Cancer Center, University of Minnesota
Musculoskeletal Syndrome
A Feasibility Study of Topical Cannabinoids for Treatment of Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) in Adults With Hormone Receptor-Positive Breast Cancer (CanAroma)
Aromatase inhibitors (AIs) are commonly used for post-menopausal women with hormone-positive breast cancer. Compared to tamoxifen, AIs improve breast cancer recurrence rates and lower 10-year breast cancer mortality.
- Trial name
- NCT05935891
- Testing
- CBD-dominant, THC dominant
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Minnesota
Stress, Stress Disorder
The Professional Peer Resilience Initiative
The Professional Peer Resilience Initiative (PPRI) study is an observational study aimed at understanding how symptoms of traumatic stress and resilience evolve over time in the University of Minnesota (UMN) healthcare workforce…
- Conditions
- Stress, Stress Disorder, Stress, Psychological, Trauma, Psychological
- Trial name
- PPRI (NCT04396600)
- Testing
- MinnRAP Peer Support Program
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma
FMBI With War-affected Families
This study has two central research questions: 1) Is implementing a family mindfulness-based intervention with war-affected immigrant families through community based participatory research methods feasible?; and 2) Does the…
- Conditions
- Family Mindfulness-based Intervention in War-affected Families, Intergenerational Trauma, War-Related Trauma
- Trial name
- NCT05241314
- Testing
- Learning to BREATHE, After Deployment Adaptive Parenting Tools (ADAPT)
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Alzheimer Disease, Dementia
A Mobile Informatics Solution to Aid in Memory
The researchers propose to develop an informatics system to assist people with memory impairment. Persons with Memory Concern (PWMC) recognize the faces they see daily, such as a spouse or caregiver, but they may confuse visiting…
- Trial name
- NCT04700540
- Testing
- Smartwatch Reminder (SR) system
- Where
- United States
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Chronic Kidney Disease, End-stage Kidney Disease
Applications of MRI in Kidney Disease
This study has two major purposes: 1. To test developed multiple anatomic and functional MRI methods; 2. To evaluate the potentials of these MRI methods in the diagnosis, prognosis, and monitoring of the progression of renal…
- Trial name
- NCT02832505
- Testing
- No intervention but only observational
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Minnesota
Hepatocellular Carcinoma, Secondary Malignant Neoplasm of Liver
Radioembolization of Primary and Secondary Liver Malignancies and The Effect On The Immune System
The goal of this study is to understand the immunologic effects radioembolization has on the immune system. This will be done by evaluating the changes on biopsy, peripheral blood monocytes, and cytokines.
- Trial name
- NCT03889093
- Testing
- Yttrium-90
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Minnesota
Cystic Fibrosis
The Impact of Insulin Therapy on Protein Turnover in Pre-Diabetic Cystic Fibrosis Patients
Insulin replacement therapy may be effective in breaking the cycle of protein catabolism, undernutrition and overall clinical deterioration in pre-diabetic, insulin insufficient CF youth because of its potent anabolic effect.
- Trial name
- NCT02496780
- Testing
- novolog insulin, levemir insulin
- Where
- 2 sites in United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Temperature Change, Body
Heated Humidification System Breathing Circuit for Maintenance of Body Temperature in Pediatric Patients
Our goal is to evaluate the efficacy of the Westmed system vs the Bair Hugger Blanket.
- Trial name
- ANAPOD (NCT03896867)
- Testing
- Anapod™ Humi-Therm Heated Humidification System Breathing Circuit, Bair Hugger™ Warming Blanket
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Psychosis
Transcranial Direct Current Stimulation and Cognitive Remediation Therapy for Psychosis
The proposed pilot study is a randomized controlled study to assess effectiveness of transcranial direct current stimulation (tDCS) to enhance cognitive remediation therapy in patients with psychotic disorders. tDCS.
- Trial name
- NCT02085421
- Testing
- tDCS
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Minnesota
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