Clinical trials: sponsored by University of Minnesota
Cardiovascular Diseases, Heart Diseases
Recycling of Chronic Smokers to Sustained Abstinence
To develop and to test a brief telephone intervention following clinic treatment for smoking cessation.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Lung Diseases
- Trial name
- NCT00005710
- Sponsor
- University of Minnesota
Alcohol Use Disorder
Brain Functional Connectivity in Alcohol Use Disorder
Due to the relapsing nature of alcoholism, excessive alcohol consumption represents a significant cost to US society ($249 billion in 20101). About 64% of those entering treatment will relapse within one year.
- Trial name
- NCT02877849
- Testing
- MRI: Brain Imaging data collection
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Wound Infection Due to Staphylococcus Aureus, MRSA Infection of Postoperative Wound
S. Aureus Screening and Decolonization
Staphylococcus aureus (SA) healthcare-associated infections (HAI) cause significant morbidity and mortality. SA causes 15% of all HAI and 30% of surgical site infections (SSIs).
- Trial name
- NCT02182115
- Testing
- antiseptic bundle, standard of care
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Lung Diseases, Lung Diseases, Obstructive
Lung Health Study II
To determine if participants with chronic obstructive pulmonary disease, who were assigned to inhaled corticosteroids had a lower rate of decline in lung function and lower incidence of respiratory morbidity compared to…
- Conditions
- Lung Diseases, Lung Diseases, Obstructive, Chronic Obstructive Pulmonary Disease
- Trial name
- LHSII (NCT00000569)
- Testing
- triamcinolone
- Volunteers
- 1,116 people
- Sponsor
- University of Minnesota
Acute Respiratory Distress Syndrome, Lung Diseases
ARDS - Clinical Epidemiology and the Role of the Inflammatory Response - SCOR in Acute Lung Injury
To investigate the epidemiology of adult respiratory distress syndrome (ARDS) and the evolution of the inflammatory process in patients with acute lung injury.
- Trial name
- NCT00005318
- Sponsor
- University of Minnesota
Tibial Fracture
SPRINT - Randomized Trial of Tibial Fracture Fixation
The purpose of this study is to determine if there is a difference in the rate of healing of a tibia fracture treated with an intramedullary nail based on whether or not the bone was reamed prior to nail insertion.
- Trial name
- NCT00038129
- Testing
- Intramedullary nail implant
- Where
- 16 sites in United States
- Volunteers
- 1,200 people
- Sponsor
- University of Minnesota
Obesity, Cardiovascular Diseases
Worksite Program to Prevent Weight Gain Among Bus Drivers
The purpose of this study is to implement and evaluate a two-year multi-component environmental intervention to prevent weight gain among city bus drivers at four bus garages.
- Conditions
- Obesity, Cardiovascular Diseases, Heart Diseases
- Trial name
- NCT00122993
- Testing
- Healthful eating and food choices behavior change programs and changes in worksite food availability and prices, Physical Activity, Environment
- Where
- United States
- Volunteers
- 1,200 people
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1
Smokers report that they often smoke cigarettes during stressful times. The combined effect of smoking and exposure to stress leads to exaggerated increases in blood pressure, heart rate and other measures of stress response.
- Trial name
- NCT00218439
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
New Moves - Obesity Prevention Among Adolescent Girls
The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity.
- Trial name
- NCT00250497
- Testing
- New Moves
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Kidney Transplant
A Study of Factors That Affect Long-Term Kidney Transplant Function
The causes of deterioration of transplanted kidney function are poorly understood. The purpose of this study is to determine the disease processes that cause transplanted kidney dysfunction and loss in patients who received a…
- Trial name
- DeKAF (NCT00270712)
- Where
- 7 sites in United States, Canada
- Volunteers
- 3,175 people
- Sponsor
- University of Minnesota
Breast Cancer, Obesity
Women in Steady Exercise Research [Formerly Women, Oxidative Stress, Exercise and Estrogens (WOSEE)]
RATIONALE: Exercising regularly may lower the risk of breast cancer. PURPOSE: This randomized clinical trial is studying how well exercise prevents breast cancer in healthy young women.
- Trial name
- WISER (NCT00393172)
- Testing
- exercise
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
The use of smokeless tobacco (ST) as a substitute for cigarette smoking has been suggested since it is considered by some to be a less harmful tobacco product (Russell, Jarvis and Feyerabend, 1980; Russell et al, 1981; Rodu…
- Trial name
- ANTS3 (NCT00469079)
- Testing
- Nicotine gum and lozenge, Taboka, Camel Snus
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Anxiety Disorders
Evaluating the Effectiveness of Early Cognitive Behavioral Therapy With or Without Parental Involvement in Treating Anxious Children
This study will evaluate the effectiveness of school-based cognitive behavioral therapy with or without parental involvement in treating anxious children.
- Trial name
- NCT00557648
- Testing
- Group CBT for children, Group CBT for children plus parent training
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Minnesota
HIV Infections
Understanding the Increased Risk of Cardiovascular Disease in People With HIV
HIV is a virus that can lead to acquired immunodeficiency syndrome (AIDS), a disease for which there is not yet a cure. Antiretroviral therapy (ART) has proven an effective treatment for inhibiting the replication of HIV…
- Trial name
- NCT00577681
- Testing
- Antiretroviral Therapy (ART)
- Volunteers
- 5,472 people
- Sponsor
- University of Minnesota
Obesity
Ready. Set. ACTION! A Theater-Based Obesity Prevention Program for Children
The goal of Ready, Set, ACTION! (RSA) is to test the feasibility of implementing a theater-based after-school program to promote healthy eating, physical activity, and positive body image with children in grades four through six.
- Trial name
- RSA (NCT00604513)
- Testing
- Ready. Set. ACTION! Protocol, Control
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
Environmental Intervention for Weight Gain Prevention
The primary aim of this research is to evaluate the efficacy of a multicomponent worksite-based, environmental intervention in reducing weight increase and obesity over time in working adults.
- Trial name
- HealthWorks (NCT00708461)
- Testing
- weight gain prevention
- Where
- United States
- Volunteers
- 1,747 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Eating Disorders
Effectiveness of Stepped Care Versus Best Available Care for Bulimia Nervosa
This study will compare the medical and cost effectiveness of a stepped approach, including self-help and drug therapies, to the current best available care for bulimia nervosa.
- Trial name
- NCT00733525
- Testing
- Cognitive Behavioral Therapy, Fluoxetine, Guided Self-Help
- Where
- 4 sites in United States
- Volunteers
- 293 people
- Sponsor
- University of Minnesota
Intermittent Claudication, Peripheral Vascular Diseases
Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial Disease (The EXERT Study)
Peripheral arterial disease (PAD) is a disorder that affects more than 8 million people in the United States. As a result of decreased blood flow to the legs, people with PAD may experience leg pain and difficulty with walking.
- Trial name
- EXERT (NCT00895635)
- Testing
- Treadmill Exercise Training, Arm Ergometry Exercise Training, Usual Care
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Minnesota
Appetite
Effect of Food Form on Satiety and Gastric Emptying
Our objective is to determine whether food form (liquid vs. solid) alters gastric emptying, satiety, and food intake, when all macronutrients and fiber are controlled.
- Trial name
- NCT01102907
- Testing
- Liquid Breakfast, Solid Breakfast Meal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cicatrix, Dermabrasion
Laser Resurfacing Versus Dermabrasion for Scar Revision
Dermabrasion has been the historical standard used for resurfacing scars on the skin. Recently, fractionated laser therapy has been FDA approved for scar resurfacing.
- Conditions
- Cicatrix, Dermabrasion, Coagulation, Laser
- Trial name
- NCT01176448
- Testing
- Fractionated laser, Dermabrasion
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Minnesota