Clinical trials: sponsored by University of Minnesota
Intermittent Claudication, Peripheral Vascular Diseases
Evaluating Two Exercise Training Programs to Reduce Leg Pain in People With Peripheral Arterial Disease (The EXERT Study)
Peripheral arterial disease (PAD) is a disorder that affects more than 8 million people in the United States. As a result of decreased blood flow to the legs, people with PAD may experience leg pain and difficulty with walking.
- Trial name
- EXERT (NCT00895635)
- Testing
- Treadmill Exercise Training, Arm Ergometry Exercise Training, Usual Care
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- University of Minnesota
Unplanned Use of Health Care Services
Telehealth Nursing Intervention for Children With Complex Health Care Needs (CCHCN)
The overall objective of this study is to evaluate the effectiveness of a telehealth care coordination and case management nursing intervention for children with complex special health care needs.
- Trial name
- NCT01328353
- Testing
- telehealth plus aprn triage
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Minnesota
Orthodontic Malocclusion
Randomized, Blinded, Controlled Clinical Trial of Surgically Facilitated Orthodontic Treatment
The purpose of this investigation is intended to evaluate the efficacy of surgically facilitated orthodontic treatment (SFO) in terms of treatment time, incidence of root shortening, and occurrence of mucogingival side effects…
- Trial name
- NCT01866345
- Testing
- Surgically facilitated Orthodontic treatment, Conventional orthodontic treatment
- Sponsor
- University of Minnesota
Cancer, Infection
Comparison of "Wet Suction" Technique to Contemporary "Dry Suction" Technique Using a 22 Gauge Needle for EUS FNA
ROLE OF SUCTION IN EUS-FNA: Current suction technique involves suctioning the aspirate into the needle that has an air column. The needle is not flushed with any liquid prior to passing into the desired solid lesion.
- Conditions
- Cancer, Infection, Inflammation, Tumor
- Trial name
- NCT01720745
- Where
- 2 sites in United States
- Volunteers
- 128 people
- Sponsor
- University of Minnesota
Portion Sizes
Portion Size Effects on Body Weight:Free Living Setting
The study purpose was to evaluate the effects of portion sizes on body weight and energy intake in a free-living setting. 223 healthy adults were recruited from an urban worksite and randomized to one of four groups for a…
- Trial name
- NCT01820403
- Testing
- portion size kcal of box lunch
- Where
- United States
- Volunteers
- 233 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Migraine, Headache
Cognitive Effects of Immediate Release Topiramate vs Extended Release Topiramate in Patients With Migraine
Crossover, randomized, double blind: Q12h dosing in both periods; matching placebo for evening dosing during XR treatment; target dose: 100mg
- Trial name
- NCT03280342
- Testing
- IR-TPM (Topamax), XR-TPM (Trokendi XR)
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Neurofibromatosis 1, Scoliosis
Genetic Evaluation of NF1 and Scoliosis Patients
Neurofibromatosis (NF) is a common genetic disorder that cause tumors to grow along various types of nerves and, in addition, can affect the development of bones and skin. It occurs in 1:4000 persons.
- Trial name
- NCT01776125
- Testing
- Cheek swab
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Minnesota
Sanfilippo Syndrome Type A, Sanfilippo Syndrome Type B
Neurobehavioral Phenotypes in MPS III
Hypothesis #1: Factor analysis of the revised Sanfilippo Behavior Rating Scale (SBRS) will identify a group of externalizing behaviors and a group of Klüver-Bucy syndrome-like behaviors as two different factors that are at least…
- Conditions
- Sanfilippo Syndrome Type A, Sanfilippo Syndrome Type B, Hurler Syndrome
- Trial name
- NCT01873911
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Minnesota
Heart Diseases, Heart Failure
Mindfulness & Stress Management Study for Cardiac Patients
The guideline-recommended standard of care for patients who have experienced a heart attack, heart failure, or other coronary event or procedure is exercise-based cardiac rehabilitation (CR).
- Conditions
- Heart Diseases, Heart Failure, Myocardial Infarction, Chronic Stable Angina
- Trial name
- NCT02722213
- Testing
- Mindfulness-Based Stress Reduction (MBSR).
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Minnesota
Hypoxia, Respiratory Distress
Advancement of Modified Bubble CPAP
This study proposes that modifying the current form of bCPAP by adjusting the nasal prongs to fit older children, will create a safe form of respiratory support that may help to decrease respiratory distress and thus mortality…
- Trial name
- NCT02208323
- Testing
- Bubble CPAP
- Where
- Uganda
- Volunteers
- 87 people
- Sponsor
- University of Minnesota
Multicomponent School Based Behavioral Intervention, Prevent Further Weight Gain and or Promote
Team COOL Pilot Study
The goal of this exploratory pilot study was to develop and test the acceptability and feasibility of an innovative alternative high school-based intervention to prevent further weight gain and/or promote weight loss among a…
- Conditions
- Multicomponent School Based Behavioral Intervention, Prevent Further Weight Gain and or Promote, Weight Loss Among Adolescents
- Trial name
- Team COOL (NCT01315743)
- Testing
- Team COOL
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
Environmental Intervention for Weight Gain Prevention
The primary aim of this research is to evaluate the efficacy of a multicomponent worksite-based, environmental intervention in reducing weight increase and obesity over time in working adults.
- Trial name
- HealthWorks (NCT00708461)
- Testing
- weight gain prevention
- Where
- United States
- Volunteers
- 1,747 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Vitamin D Deficiency
Vitamin D Levels Following Topical Application of Vitamin D Ointment
This is a pre-post open label trial to assess the change in Vitamin D blood levels following treatment with three doses of topical Vitamin D3 in subjects with existing Vitamin D deficiency.
- Trial name
- VITD-001 (NCT02676674)
- Testing
- Dose 1, Dose 2
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sit-Stand Workstations
Increasing Workplace Physical Activity in Sedentary Office Workers
Purpose: The purpose of this study is to implement and evaluate a randomized controlled trial in sitting office workers to reduce sitting time through the use of motorized and non-motorized sit/stand workstations as well as a…
- Trial name
- NCT01846013
- Testing
- Stand, Move, Stand and Move
- Where
- 3 sites in United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Parkinson's Disease, Gaucher's Disease
Intravenous N-acetylcysteine for the Treatment of Gaucher's Disease and Parkinson's Disease
The investigators are interested in determining if the investigators are able to detect changes in brain chemistry using Magnetic Resonance Spectroscopy (MRS) in individuals with Parkinson's disease (PD), those with Gaucher's…
- Trial name
- NCT01427517
- Testing
- N-acetylcysteine
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Breast Cancer, Obesity
Women in Steady Exercise Research [Formerly Women, Oxidative Stress, Exercise and Estrogens (WOSEE)]
RATIONALE: Exercising regularly may lower the risk of breast cancer. PURPOSE: This randomized clinical trial is studying how well exercise prevents breast cancer in healthy young women.
- Trial name
- WISER (NCT00393172)
- Testing
- exercise
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
New Moves - Obesity Prevention Among Adolescent Girls
The New Moves study will evaluate the impact of a school based program for inactive high school girls who are overweight or at risk for being overweight due to low levels of physical activity.
- Trial name
- NCT00250497
- Testing
- New Moves
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Nicotine Dependence
Health Effects of SLT, Cigarette Smoking, and New Tobacco Products
The use of smokeless tobacco (ST) as a substitute for cigarette smoking has been suggested since it is considered by some to be a less harmful tobacco product (Russell, Jarvis and Feyerabend, 1980; Russell et al, 1981; Rodu…
- Trial name
- ANTS3 (NCT00469079)
- Testing
- Nicotine gum and lozenge, Taboka, Camel Snus
- Where
- United States
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Breast Cancer
Prospective Radiologic Evaluation of Changes Following Fat Grafting
Breast implants are currently used for cosmetic breast augmentation and in breast reconstruction following mastectomy for breast cancer.
- Trial name
- NCT01343030
- Where
- 2 sites in United States, France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Sickle Cell Disease
Functional Neuroimaging of Pain Using EEG and fMRI
The purpose of this research is to use non-invasive imaging technologies to study how the human brain processes pain. The investigators will use contact heat to induce pain and record data scalp EEG and functional magnetic…
- Trial name
- NCT02212691
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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