Clinical trials: sponsored by University of Minnesota
Obesity
Location of GLP-1 Release
Background: Physicians do not have a unified, scientifically tested theory of causation for obesity and its comorbidities, nor do they have explanations for the mechanics of the metabolic/bariatric surgery procedures.
- Trial name
- NCT02036710
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Autism Spectrum Disorders
Intranasal Oxytocin and Learning in Autism
: The objective of this study is to determine the tolerability and therapeutic potential of oxytocin in children and adolescents with Autism Spectrum Disorders (ASD) when paired with a computer game intervention that is designed…
- Trial name
- NCT02090829
- Testing
- Syntocinon (synthetic oxytocin)
- Where
- United States
- Sponsor
- University of Minnesota
Epistaxis, Hereditary Hemorrhagic Telangiectasia
Office-sclerotherapy for Epistaxis Due to Hereditary Hemorrhagic Telangiectasia
The purpose of this study is to test a novel and tolerable office-based treatment method, sclerotherapy with sodium tetradecyl sulfate, for recurrent epistaxis (nosebleeds) related to Hereditary Hemorrhagic Telangiectasia (HHT)…
- Trial name
- NCT01408732
- Testing
- Sclerotherapy, Standard Treatment
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Minnesota
Prolapse, Urinary Incontinence
What is the Prevalence of Female Pelvic Floor Disorders in Minnesota?
To determine the prevalence of pelvic organ prolapse and urinary incontinence among women in Minnesota using a short web-based self-administered questionnaire.
- Conditions
- Prolapse, Urinary Incontinence, Fecal Incontinence, Bladder Pain Syndrome
- Trial name
- NCT03536221
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Appetite
Effect of Food Form on Satiety and Gastric Emptying
Our objective is to determine whether food form (liquid vs. solid) alters gastric emptying, satiety, and food intake, when all macronutrients and fiber are controlled.
- Trial name
- NCT01102907
- Testing
- Liquid Breakfast, Solid Breakfast Meal
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Physical Inactivity
Mindful Movement for Physical Activity and Wellbeing in Older Adults
Physical inactivity has reached pandemic proportions and is associated with increased morbidity, mortality, and healthcare costs.
- Trial name
- NCT03114709
- Testing
- Mindful Movement, 10 Keys to Health & Wellbeing
- Where
- 3 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
EBV Viremia, CMV Viremia
Treating Kidney Donors With Valganciclovir to Reduce Viral Transmission to Recipients
The aim of our study is to reduce viral (CMV and EBV) transmission from donor to recipient. The discovery that anti-retroviral therapy to mothers with HIV reduced transmission of the virus to their babies was pivotal to the…
- Trial name
- NCT01329185
- Testing
- Valganciclovir
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Minnesota
Acute Respiratory Distress Syndrome, Lung Diseases
ARDS - Clinical Epidemiology and the Role of the Inflammatory Response - SCOR in Acute Lung Injury
To investigate the epidemiology of adult respiratory distress syndrome (ARDS) and the evolution of the inflammatory process in patients with acute lung injury.
- Trial name
- NCT00005318
- Sponsor
- University of Minnesota
Weight Loss
Weight Tracking and Weight Loss Outcomes: Establishing the Standard of Care
To achieve the long term goal of strengthening behavioral weight loss programs, the purpose of this project is to test an enhanced, daily weight tracking instruction against the current standard of care (weekly weight tracking)…
- Trial name
- Tracking (NCT01646086)
- Testing
- 12 month behavioral weight loss intervention
- Where
- United States
- Volunteers
- 339 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Tobacco Use Disorder
Effect of Paroxetine on Smokers' Cardiovascular Response to Stress - 1
Smokers report that they often smoke cigarettes during stressful times. The combined effect of smoking and exposure to stress leads to exaggerated increases in blood pressure, heart rate and other measures of stress response.
- Trial name
- NCT00218439
- Testing
- Paroxetine
- Where
- United States
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Eating Disorders
Effectiveness of Stepped Care Versus Best Available Care for Bulimia Nervosa
This study will compare the medical and cost effectiveness of a stepped approach, including self-help and drug therapies, to the current best available care for bulimia nervosa.
- Trial name
- NCT00733525
- Testing
- Cognitive Behavioral Therapy, Fluoxetine, Guided Self-Help
- Where
- 4 sites in United States
- Volunteers
- 293 people
- Sponsor
- University of Minnesota
Stroke
Ankle Tracking Training in Stroke
The purpose of this study is to compare the improvement in ankle control and brain activation in subjects with stroke resulting from two different forms of telerehabilitation: tracking training, emphasizing accurate movements…
- Trial name
- NCT01298583
- Testing
- ankle tracking training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Minnesota
Wound Infection
A Randomized Trial of Ostomy Closure Techniques
Stoma closure has been associated with a high rate of surgical site infection (SSI). The rate for SSI following stoma closure has been noted to be 7-41%; a rate that is higher than expected for a clean-contaminated operative…
- Trial name
- NCT01713452
- Testing
- Purse string closure, Primary closure
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Minnesota
Smoking
Palatability of Experimental Cigarettes - Study 2
Smoking remains a leading cause of preventable disease and premature death worldwide. Approximately 1 out of every 5 deaths is associated with cigarette smoking, and roughly half of all daily smokers will die prematurely from…
- Trial name
- NCT01568905
- Testing
- Low level nicotine cigarette, Intermediate nicotine level cigarette, High level nicotine cigarette
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Osteoarthritis, Knee, Quality of Life
Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study
The study hypothesized that it is feasible and safe to use Hatha yoga in older women with knee osteoarthritis (OA), and practicing Hatha yoga regularly will help reduce pain and stiffness, enhance physical function, and improve…
- Conditions
- Osteoarthritis, Knee, Quality of Life, Poor Quality Sleep, Physical Impairment
- Trial name
- NCT01832155
- Testing
- Hatha yoga
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Epilepsy
A Study of Diazepam After Intranasal and Intravenous Administration to Healthy Volunteers
The purpose of this clinical research study is to assess the bioavailability and pharmacokinetics of two formulations of diazepam after intranasal (nasal spray) and injectable diazepam after intravenous (I.V.) administration
- Trial name
- NCT01364558
- Testing
- Diazepam
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
HIV Infections
Understanding the Increased Risk of Cardiovascular Disease in People With HIV
HIV is a virus that can lead to acquired immunodeficiency syndrome (AIDS), a disease for which there is not yet a cure. Antiretroviral therapy (ART) has proven an effective treatment for inhibiting the replication of HIV…
- Trial name
- NCT00577681
- Testing
- Antiretroviral Therapy (ART)
- Volunteers
- 5,472 people
- Sponsor
- University of Minnesota
Hallux Valgus, Instability of the Foot Arch
Measurement of Arch Motion After Bunion Surgery
This study is an observational "change from baseline" outcome measures design. Data is collected for the sake of evaluating treatment (fusion surgery) performed as standard medical care, but the investigator does not assign…
- Trial name
- NCT02074748
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Clostridium Difficile
Observational Study of C. Diff in Post-Transplant Patients
The primary objective of this observational study is to estimate the 90-day response rates to treatment for a first episode of C. difficile infections (CDI) in adult transplant recipients.
- Trial name
- CDIFF (NCT02747017)
- Where
- 9 sites in United States, Argentina and 3 more
- Volunteers
- 132 people
- Sponsor
- University of Minnesota
Anorexia Nervosa, Bulimia Nervosa
Yoga in the Treatment of Eating Disorders: a Randomized Trial
Yoga facilitates the treatment of eating disorders by decreasing symptom severity over time.
- Trial name
- TEP (NCT02191995)
- Testing
- yoga
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
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