Clinical trials: sponsored by University of Nebraska
Premature Infants
Serum 25-hydroxy Vitamin D [25(OH)D] Levels, Supplemental Vitamin D, and Parathyroid Hormone Levels in Premature Infants
This study will determine levels of vitamin D supplementation to achieve goal serum 25-hydroxy vitamin D [25(OH)D] levels of 30 ng/mL, and to define serum 25(OH)D levels required to achieve suppression of parathyroid hormone in…
- Trial name
- NCT01469650
- Testing
- cholecalciferal, cholecalciferol
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Nebraska
Age-related Macular Degeneration
Evaluation of the Distortion Correction Data Collection (DCDC) App Software
The purpose of the research study is to evaluate how well the Distortion Correction Data Collection (DCDC) App works. The DCDC App is an experimental software application that is being developed at the University of Nebraska…
- Trial name
- NCT02337647
- Testing
- DCDC App
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Nebraska
Nasal Sinus; Inflammation, Opioid Abuse
Pain Management Following Sinus Surgery
This Study evaluates the effect of adding Non-steroidal anti-inflammatories (NSAIDs) to the post-operative pain management of sinus surgery patients and wether or not this addition reduces or eliminates the need for narcotic pain…
- Conditions
- Nasal Sinus; Inflammation, Opioid Abuse, Pain, Postoperative
- Trial name
- NCT03822962
- Testing
- Ibuprofen 600Mg Tablet, Standard Regimen | Tylenol
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Urticaria, Angioedema
Vitamin D Levels in Subjects With Chronic Urticaria and Angioedema
The objective of this study is to perform an exploratory analysis to determine if a possible relationship between vitamin D and chronic urticaria and/or angioedema exists.
- Trial name
- NCT00876369
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Neovascular Macular Degeneration
Pharmacokinetic Study of Intravitreal Aflibercept Injection in Eyes With Wet Age-related Macular Degeneration
The main goal is to study way that aflibercept injection behaves in the eye and in the body of patients with wet macular degeneration, in patients who have had previous vitreous removal surgery.
- Trial name
- DRAW (NCT02204683)
- Testing
- Aflibercept
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Nebraska
Body Weight Changes
Weight Maintenance Through Physical Activity and Social Support in Rural Middle-Aged Women
The purpose of this study is to compare an technology-based weight maintenance intervention using action plans, videos discussion boards and health behavior tracking (weight, calories in and out, pedometer steps) with a…
- Trial name
- NCT01487538
- Testing
- Videos, Action Plans, Discussion Boards
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Cardiovascular Risk Factor
Care4U: Self Management Intervention for Older Adult Caregivers
Older adults caring for others often neglect their own health. This research is being done to see if helping caregivers focus on their own needs can improve their health and ability to care for others
- Trial name
- NCT01764399
- Testing
- Care4U
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Nebraska
Multiple Sclerosis
Influence of Exercise on the Mobility and Balance of Individuals With Multiple Sclerosis
Outcomes from the investigators' recent investigation suggested that a high dosage of challenging physical therapy exercises can result in clinically improvements in the postural balance and walking speed of individuals with MS.
- Trial name
- NCT02524483
- Testing
- Therapeutic Challenge Program, Therapeutic Exercise Program
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Nebraska
Surgical Site Infection
Detection of Staph Colonization in Pre-op Arthroplasty Patients
This study will evaluate which body site(s) provide the best source of possible staph presence in participants undergoing total joint arthroplasty.
- Trial name
- Staph (NCT01648088)
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Thyroid Cancer
Optimal Measurement of Thyroglobulin Measurement Following Thyroidectomy
The optimal timing to measure thyroglobulin(Tg) after thyroidectomy is unknown in patients with thyroid cancer. The ATA and NCCN guidelines are not specific on optimal timing of Tg levels in post-op state and suggest anywhere…
- Trial name
- NCT02347683
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Gastroesophageal Reflux Disease, Hiatal Hernia
Long-term Outcome of Laparoscopic Hiatal Hernia Repair With or Without Alloderm Mesh at a University Hospital
To study the long term outcome of Laparoscopic Hiatal Hernia Repair with human acellular dermal matrix Alloderm (LifeCell, Branchburg, NJ) mesh.
- Conditions
- Gastroesophageal Reflux Disease, Hiatal Hernia, Paraesophageal Hernia
- Trial name
- NCT01776827
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Nebraska
Rheumatoid Arthritis
Rheumatoid Arthritis Comorbidity: Bone Health in Men and African Americans
The objective of the proposed study is to assess bone health and determinants of bone health among select subpopulations of rheumatoid arthritis patients.
- Trial name
- NCT00595894
- Where
- United States
- Volunteers
- 1,745 people
- Sponsor
- University of Nebraska
Healthy
Impact of a High-fat Meal on Assessment of Clopidogrel-induced Platelet Inhibition in Healthy Subjects
The purpose of this study is to determine whether a high-fat meal affects the ability of platelet function tests to measure platelet inhibition by clopidogrel.
- Trial name
- NCT01307657
- Testing
- high fat meal
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Lymphoma
Rituximab & Combination Chemotherapy Followed by Transplantation in Relapsed or Refractory Non-Hodgkin's Lymphoma
RATIONALE: Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells.
- Trial name
- NCT00007852
- Testing
- rituximab, carmustine, cytarabine
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Nebraska
HIV, Contraception
A Pharmacokinetic Evaluation of Levonorgestrel Implant and Antiretroviral Therapy
The use of hormone contraception poses a significant challenge for the estimated 16 million HIV-infected women of childbearing age.
- Trial name
- NCT01789879
- Testing
- Levonorgestrel, Nevirapine, Efavirenz
- Where
- Uganda
- Volunteers
- 60 people
- Sponsor
- University of Nebraska
Vision Loss
First-Sight Refractive Error Correction in the Developing World
The aim of this study is to test the efficacy of the First-Sight refractive kit designed to provide refractive correction of simple hyperopia, myopia and astigmatism with autorefraction.
- Trial name
- NCT01598818
- Where
- 2 sites in United States, Haiti
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Breast Cancer
Effect of Tamoxifen or an Aromatase Inhibitor on Estrogen Metabolism in Women Treated for Newly Diagnosed Breast Cancer
RATIONALE: Studying samples of urine in the laboratory from women with breast cancer may help doctors learn whether tamoxifen and aromatase inhibitors alter the metabolism of estrogens.
- Trial name
- NCT00569543
- Testing
- high performance liquid chromatography, laboratory biomarker analysis, mass spectrometry
- Where
- 2 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Nebraska
Normal Tension Glaucoma
IOP Lowering Effects of Topical Anesthetics Used Frequently in the Ophthalmology Clinic
The primary purpose of this study is to determine whether topical ophthalmic anesthetics lower the intraocular pressure in the eye.
- Trial name
- NCT01254149
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Rheumatoid Arthritis
Gene-Environment Interactions in Rheumatoid Arthritis Autoimmunity Disease Severity
The objective of the proposed study is to assess the role of smoking and complex gene-smoking interactions in two understudied Rheumatoid Arthritis (RA)groups.
- Trial name
- NCT00594451
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Nebraska
Heart Failure
Heart Failure Exercise And Resistance Training Camp (HEART Camp)
The purpose of this feasibility study was to obtain pilot data, as the basis for a future, larger investigation, testing the impact of an innovative training camp intervention called HEART CAMP (Heart failure Exercise And…
- Trial name
- HEART (NCT01771900)
- Testing
- Heart Camp Group, Attention Control Group
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Nebraska