Clinical trials: sponsored by University of Nebraska
Uveitis
Grading Scale of Vitreous Haze in Patients With Uveitis Using Ultrasonography
This study is aimed at creation and validation of a vitreous haze scoring system using ultrasonography B-scan of the eye. Images will be obtained from patients with uveitis and quantification of inflammation will be done to…
- Trial name
- NCT02311192
- Testing
- Ultrasonography B-scan
- Sponsor
- University of Nebraska
Alzheimer Disease, Early Onset, Mild Cognitive Impairment
Effects of Mitochondrial-targeted Antioxidant on Mild Cognitive Impairment (MCI) Patients
Neurodegenerative diseases such as Mild Cognitive Impairment, Alzheimer's, and dementia affect millions of Americans. Although these diseases are heavily researched, there is very little research examining the impact of…
- Trial name
- NCT03514875
- Testing
- MitoQ
- Sponsor
- University of Nebraska
Cardiovascular Diseases
Effects of Oral Antioxidant Cocktail in Cardiovascular Disease Patients
Title: Effects of oral antioxidant cocktail on vascular function and muscle function in cardiovascular disease patients Cardiovascular disease (CVD) generally refers to various conditions involving narrowed or blocked…
- Trial name
- NCT03629613
- Testing
- Oral antioxidant cocktail, Baseline
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Wounds, Infection
Autologous Platelet Gel in Wound Healing of Coronary Artery Bypass Grafting (CABG) Patients
This study will determine if autologous platelet gel (APG) on sternal incision and conduit sites will improve wound healing and decrease infection in coronary artery bypass grafting surgery patients.
- Trial name
- NCT00672672
- Testing
- autologous platelet gel
- Sponsor
- University of Nebraska
Uterus Transplant
Initiation of a Deceased Donor Uterine Transplantation Program at the University of Nebraska Medical Center
This study will explore the feasibility of initiating a uterine transplant program at UNMC. Using the procedural templates established by a successful Swedish team, the investigators will identify emotionally and socially stable…
- Trial name
- NCT02409147
- Testing
- Uterine Transplant
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Cerebral Vasospasm, Subarachnoid Hemorrhage
Safety Study of Sildenafil in Treatment of Cerebral Aneurysm Vasospasm
Rupture of a cerebral aneurysm is a serious medical condition that may result in permanent disability or even death just related to the aneurysm rupture itself.
- Trial name
- NCT00871065
- Testing
- Sildenafil citrate
- Sponsor
- University of Nebraska
Diarrheal Episodes
Evaluate the Effect of Planet Water Foundation's Clean Water, Sanitation and Hygiene Intervention
The objective of the study is to evaluate the impact of the Planet Water Foundation's intervention to improve Water, Sanitation and Hygiene related illness for reducing absenteeism and diarrheal episodes among school children…
- Trial name
- NCT02015325
- Testing
- Planet Water Foundation's Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Acute Coronary Syndrome, Myocardial Infarction
Utilization of Diagnostic Ultrasound in the Detection and Therapy of Acute Coronary Syndromes
The study will see if mechanical impulses delivered by an echocardiographic probe during a continuous infusion of MRX 801 are capable of improving blood flow in smaller heart vessels in patients with acute coronary syndromes.
- Trial name
- NCT00955136
- Testing
- Use of intermittent high MI impulses during echocardiogram
- Sponsor
- University of Nebraska
Arthritis
Total Shoulder Replacement Outcomes With Autologous Bone Graft as Fixator for Glenoid Anchor Peg.
We hypothesize that there will be a low incidence of glenoid loosening with a total shoulder arthroplasty using an anchor peg glenoid and autologous bone grafting.
- Trial name
- Glenoid (NCT02136251)
- Sponsor
- University of Nebraska
Feeding; Difficult, Newborn, Necrotizing Enterocolitis
A Multi-strain Synbiotic Versus a Multi-strain Probiotic in Premature Infants
The aims are to 1) compare two probiotic treatments (multi-strain synbiotic vs. multi-strain probiotic) on bifidobacteria fecal colonization counts at 1, 2, 3, and 4 weeks of life, 34 weeks corrected gestation age (CGA) ; 2)…
- Trial name
- NCT01337921
- Testing
- Multi-strain Probiotic
- Sponsor
- University of Nebraska
Recurrent Prostate Cancer, Stage I Prostate Cancer
Atorvastatin Calcium in Preventing Metabolic Syndrome in Prostate Cancer Patients Receiving Androgen-Deprivation Therapy
This randomized pilot clinical trial studies atorvastatin calcium in preventing metabolic syndrome in patients with prostate cancer receiving long-term androgen-deprivation therapy.
- Conditions
- Recurrent Prostate Cancer, Stage I Prostate Cancer, Stage IIA Prostate Cancer, Stage IIB Prostate Cancer
- Trial name
- NCT01555632
- Testing
- atorvastatin calcium
- Sponsor
- University of Nebraska
Peripheral Vascular Disease
Lower Extremity Regional Anesthesia and Infrainguinal Bypass Grafting
In this investigation, the investigators will attempt to demonstrate that patients who have received nerve blocks (regional anesthesia) prior to open surgical vascular bypass of the lower extremities (infrainguinal bypass…
- Trial name
- NCT01803165
- Testing
- Single shot femoral and sciatic nerve block
- Sponsor
- University of Nebraska
Lung Cancer
Clearance of NNAL and Cotinine From Second-hand Smoke in Hair and Urine
This study will investigate how long it takes for NNAL and cotinine, markers of second hand smoke, to clear the human body.
- Trial name
- NNAL (NCT00863824)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Chronic Myeloproliferative Disorders, Leukemia
Donor Stem Cell Transplant, Pentostatin, and Total-Body Irradiation in Treating Patients With Hematological Cancer
RATIONALE: Giving low doses of chemotherapy and total-body irradiation before a donor peripheral blood stem cell transplant helps stop the growth of cancer cells.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Myelodysplastic Syndromes
- Trial name
- NCT00816413
- Testing
- cyclosporine, mycophenolate mofetil, pentostatin
- Sponsor
- University of Nebraska
Cesarean Section
Best Incision Site for Obese Patients - Low Versus High Transverse
Retrospective chart review using both out patient and inpatient records of obese patients (BMI of 30 or greater) who have had a cesarean section since the year 2009.
- Trial name
- NCT03041220
- Testing
- cesarean section
- Sponsor
- University of Nebraska
Short Bowel Syndrome
Pharmacokinetics of Citalopram in Patients With Short Bowel Syndrome
This study will look at how the body interacts with citalopram in adult participants with short bowel syndrome. While information on depression in patients with short bowel syndrome is sparse, the investigators' experience is…
- Trial name
- NCT00876226
- Testing
- Citalopram
- Sponsor
- University of Nebraska
Peritoneal Neoplasms, Echocardiography Guided Fluid Management
Comparison of Traditional and Echocardiography Guided Fluid Management During Cytoreductive Surgery With HIPEC
Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) is performed in patients with peritoneal tumors. Classically, this procedure is prolonged in duration and involves significant fluid shifts.
- Trial name
- NCT01225757
- Testing
- Echocardiogram
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Diffuse and Focal Abnormalities of the Liver and Pancreas
Abdominal MR Imaging at 3.0T: Sequence Optimization and Implementation
This project will facilitate the optimization of body MR imaging at 3 Tesla.
- Trial name
- NCT01007357
- Testing
- Body MR imaging
- Where
- 2 sites in United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Pain, Postoperative, Postoperative Nausea and Vomiting
Post-tonsillectomy Pain Control in Adults
This is a randomized prospective study to determine the optimal postoperative pain medication regimen for adults (18 years old and older) undergoing tonsillectomy with or without adenoidectomy for chronic tonsillitis and/or…
- Conditions
- Pain, Postoperative, Postoperative Nausea and Vomiting, Postoperative Hemorrhage, Body Weight Changes
- Trial name
- NCT02358850
- Testing
- Norco (Hydrocodone and Acetaminophen), Percocet (Oxycodone and Acetaminophen), Dilaudid (hydromorphone)
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Alcoholic Intoxication
Alcohol Myopia, Objectification, and Sexual Assault
The present project integrates previous research on factors associated with alcohol-involved sexual assault, with research on how intoxication alters attention and social perceptions in ways that increase the risk of sexual…
- Trial name
- NCT03956238
- Testing
- Alcohol intoxication, Objectification
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln