Clinical trials: sponsored by University of Nebraska
Anterior Cruciate Ligament Injuries, Knee Osteoarthritis
Optimizing Movement After Anterior Cruciate Ligament Injury
Fifty percent of teenagers and young adults who suffer an anterior cruciate ligament (ACL) injury develop knee osteoarthritis (OA) within 15 years.
- Trial name
- NCT05363683
- Testing
- Squat Biofeedback, Standard Care
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Nebraska
Ankle Injuries
Neurophysiology of Ankle Instability
Chronic ankle instability (CAI) is a common debilitating orthopedic condition that disrupts physical function and decreases quality of life. Not all CAI is the same.
- Trial name
- NCT06576687
- Testing
- Physical Rehabilitation
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Wound Heal
Porcine Membrane vs Bovine Wound Dressing in Human Tooth Extraction Sites
The purpose of this study is to compare porcine collagen membrane and bovine collagen wound dressing in human tooth extraction sites. The outcomes measured will be soft tissue thickness changes as well as bone density changes.
- Trial name
- NCT05802602
- Testing
- Porcine Collagen Membrane, Bovine Collagen Dressing
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Childhood Obesity
Family Connections: Cultural Adaptation and Feasibility Testing for Rural Latino Communities
There are marked ethnic and rural-urban disparities in the prevalence of childhood obesity (CO). Among Latino/Hispanic children, CO is almost 60% higher than that of non- Latino/Hispanic Whites, and among children in rural areas…
- Trial name
- NCT04731506
- Testing
- Family Connections
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Nebraska
Dietary Intervention, Gut Microbiota
Effects of Distinct Nebraska-Dry Bean Market Classes on Gut Microbiota
Beans are well known for their health benefits. Many of these benefits relate to gut health, as many of the nutrients found in beans support beneficial microbes that live in the gut.
- Trial name
- NCT06935435
- Testing
- Pink Beans, Great Northern Beans, Five-Bean Mixture
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Diabetes Mellitus, Type 2, PreDiabetes
Blood Markers of Early Pancreas Cancer
Identifying biomarkers of early pancreatic ductal adenocarcinoma (PDAC) could facilitate screening for individuals at higher than average risk and expedite the diagnosis in individuals with symptoms and substantially improve an…
- Conditions
- Diabetes Mellitus, Type 2, PreDiabetes, Pancreas Cyst, Chronic Pancreatitis
- Trial name
- NCT03568630
- Where
- United States
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Behavior, Health Risk, Implementation Science
Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation
This study aims to evaluate the feasibility and compare the preliminary effect of vaping cessation program consisting of media literacy education and real-time text messaging support and leverage insights from behavioral…
- Conditions
- Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking
- Trial name
- NCT05586308
- Testing
- Text-massaging suport, Financial incentive, Media literacy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Opioid Use, Opioid Use, Unspecified
Patient Utilization of Opioid Destruction Bags in the Post-op Period
This is a study on how patients use and store opioid pain medications at home after surgery and what happens to left over pills when patients are done taking them.
- Conditions
- Opioid Use, Opioid Use, Unspecified, Patient Empowerment, Total Knee Arthoplasty
- Trial name
- NCT05875857
- Testing
- Opioid destruction education
- Where
- United States
- Volunteers
- 163 people
- Sponsor
- University of Nebraska
Health, Subjective, Work Related Stress
Evaluation of the CHIME Intervention for Improving Early Head Start/Head Start Educator Well-being
This study will test how well a mindfulness-based intervention called CHIME improves the emotional well-being of educators in Early Head Start and Head Start (EHS/HS) settings.
- Conditions
- Health, Subjective, Work Related Stress, Compassion, Social Skills
- Trial name
- CHIME (NCT05791825)
- Testing
- Cultivating Healthy Intentional Mindful Educators
- Where
- United States
- Volunteers
- 571 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Meningioma, Refractory Meningioma
A Study of ONC201 for Refractory Meningioma
The goal of this clinical trial is to learn about treatment for a type of brain tumor called a meningioma. This study will enroll two groups of people.
- Conditions
- Meningioma, Refractory Meningioma, Relapsed Meningioma
- Trial name
- NCT06012929
- Testing
- ONC201
- Sponsor
- University of Nebraska
Gait
The Role of Perturbed Auditory Information for Self-motion in Gait
As people walk and interact with objects such as when opening a door, their movements make sounds. It is possible that these sounds are also used as feedback to stabilize and adapt movement.
- Trial name
- NCT05713383
- Testing
- Auditory Feedback
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
HFpEF - Heart Failure With Preserved Ejection Fraction
HEART Camp Connect -Promoting Exercise in Adults With Heart Failure With Preserved Ejection Fraction
The goal of this study is to learn more about patients with heart failure with preserved ejection fraction (HFpEF) and exercise.
- Trial name
- NCT05784753
- Testing
- HEART Camp, HEART Camp Connect
- Where
- 3 sites in United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Acute Disruption of Ankle Syndesmosis
Comparison of Gait in Syndesmosis Injuries Treated With Screw Fixation vs Suture Button
Injuries to the distal tibiofibular syndesmosis are common and occur in an estimated 25% of all rotational ankle fractures. Anatomic reduction of the syndesmosis has been associated with improved functional outcome as well as…
- Trial name
- NCT04972578
- Testing
- Suture Button vs Screw Fixation
- Where
- 3 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Primary Brain Tumor, Metastatic Brain Tumor
Assessment of Eloquent Function in Brain Tumor Patients
Purpose of the study: AIM 1: Prospectively collect pre-operative [functional magnetic resonance imaging (fMRI), diffusion tensor imaging (DTI), magnetoencephalography (MEG)] and intra-operative mapping data in patients with…
- Trial name
- NCT01535430
- Testing
- Brain mapping
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Nebraska
Obesity
Modifiable Predictors of Neural Vulnerabilities for Obesity
The purpose of this study is to examine patterns of neural activation in a priori selected brain regions associated with reward process during anticipation and delivery of appetizing food stimuli (milkshake sips) among young…
- Trial name
- NCT04522947
- Testing
- Milkshake fMRI
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Stem Cell Transplant Complications
The Patients' Experience After Stem Cell Transplant
This study will examine how adults ≥ 60 years old thinking and memory abilities are affected by stem cell transplant; whether these changes affect day-to-day activities and quality of life and how thinking and memory abilities…
- Trial name
- NCT03454568
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Nebraska
Dietary Intervention, Dietary Proteins
Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption
The goal of this clinical trial is to learn if eating more lean pork will lead to better cognition and a healthier brain in older adults.
- Conditions
- Dietary Intervention, Dietary Proteins, Dietary Assessment, Older Adults (65 Years and Older)
- Trial name
- NCT07031076
- Testing
- Ready-to-eat lean pork in frozen, 5-oz packages
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Women, Reproductive Age
Enhancing Uptake of Preconception Care Services in Family Practice Clinics Using a Patient Centered Screening Tool
Sixteen years have passed since the Centers for Disease Control recommended routine preconception screening and counseling in primary care settings, yet time constraints and low preconception counseling adherence have prevented…
- Trial name
- NCT06582160
- Testing
- Risk-Based Pre-conception Screening, Patient-centered Pre-conception Screening
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Heart Failure With Preserved Ejection Fraction
HEART Camp Connect: A Feasibility Study
This study builds on the tested and refined HEART Camp intervention which has been shown to improve long-term adherence to exercise in individuals diagnosed with heart failure.
- Trial name
- NCT05985395
- Testing
- HEART Camp Connect
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Parkinson Disease
Biomarker Assessments of Leukine During Treatment of Parkinson's Disease
First, the investigators will determine the safety of a 36 month regimen of Leukine administered as a weight-based dose at 3 µg/kg/day for 5 days (week), followed by a 2-day holiday (weekend).
- Trial name
- NCT03790670
- Testing
- sargramostim
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska