Clinical trials: sponsored by University of Nebraska
Wound Heal
Periodontal Inflammation and Wound Healing in Multiple Extractions
Four participants requiring multiple dental extractions will be recruited for this study. Two participants will be 21-50 years old, two participants will be 65-80 years old.
- Trial name
- NCT06185114
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska
Irritable Mood
Dose Response Relationship of Oxytocin on Irritability in Youths
The proposed study is a randomized, double-blind proof of concept (PoC) study on the neural impact of intranasal oxytocin (OXT) administration for adolescents (age 14 to 18), demonstrating a clinically significant level of…
- Trial name
- NCT03863288
- Testing
- Functional MRI (fMRI), Oxytocin Intranasal Spray 8 International Unit (8IU), Oxytocin intranasal spray 24 International Unit (24IU)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Nebraska
Hyposmia, Anosmia
Theophylline Nasal Spray for PD-Related Hyposmia and Anosmia
The goal of this study is to learn if intranasal theophylline (CYR-064) improves sense of smell in participants with hyposmia or anosmia related to the onset of Parkinson's Disease.
- Trial name
- NCT06498687
- Testing
- CYR-064
- Sponsor
- University of Nebraska
Adverse Childhood Experiences, Domestic Violence
The Impact of an Adapted Version of the Strengthening Families Program on IPV Among Caregivers and ACEs Among Children
Adverse childhood experiences (ACEs) are unfortunately common and the known outcomes are concerning. However, very little is currently known about programs that may prevent ACEs among children, such as witnessing intimate partner…
- Trial name
- NCT05129501
- Testing
- Experimental
- Where
- United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
COVID 19, ARDS
Stellate Ganglion Blockade in Corona Virus 2019 (COVID-19) Positive Patients
This study will establish the safety and efficacy of using stellate ganglion blocks in patients with acute respiratory distress syndrome (ARDS) due to COVID-19 disease.
- Trial name
- NCT04445337
- Testing
- Stellate Ganglion Block
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Nebraska
Hearing Loss
Restoration of Spectral Resolution With Hearing-aid Amplification
The objective of this study protocol is to determine the efficacy of using aided measures of spectral resolution to set the dynamic range of hearing with hearing-aid amplification.
- Trial name
- NCT03850678
- Testing
- Hearing Aid
- Where
- United States
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Coronary Artery Disease, Myocardial Perfusion Abnormalities
Regadenoson R-T Perfusion Imaging Trial
To exam the feasibility and accuracy of Regadenoson real time perfusion (RTPE) Imaging during vasodilator stress with Regadenoson for detection of significant coronary artery disease (CAD) in patients scheduled to undergo…
- Trial name
- NCT00837369
- Testing
- Regadenoson
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Nebraska
Acute Lymphoblastic Leukemia (ALL), Critical Illness
Animal Assisted Interactions With Animal Robot in the Intensive Care Unit (ICU)
The purpose of this study is to: 1. Establish the feasibility and acceptability of a therapeutic robot, Paro, for critically ill patients admitted to the Pediatric Intensive Care Unit 2.
- Conditions
- Acute Lymphoblastic Leukemia (ALL), Critical Illness, Physical Therapy Modalities, Occupational Therapy
- Trial name
- PARO (NCT05075395)
- Testing
- PARO therapy seal
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Nebraska
Peripheral Arterial Disease, Peripheral Artery Disease
Dietary Nitrate Supplementation and Thermoregulation
This is a double-blinded, randomized, crossover design study to assess the effects of dietary nitrate supplementation (beetroot juice) on peripheral artery disease (PAD) patients (ages 50-85) diagnosed with Fontaine stage I or II…
- Trial name
- NCT03506646
- Testing
- Beet root juice
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Nebraska
Liver Cancer
Stereotactic Radiation Therapy in Treating Patients With Advanced Liver Cancer
This is a phase I trial studying the side effects and best dose of stereotactic radiation therapy (SRT) in treating patients with advanced liver cancer.
- Trial name
- NCT00607828
- Testing
- stereotactic body radiation therapy
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Nebraska
Cigarette Smoking, Nicotine Dependence
Smokers' Response to Nicotine Dependence Genotyping
Innovative strategies to reduce adult smoking prevalence include using genetic information to motivate cessation and, ultimately, to tailor cessation pharmacotherapy.
- Trial name
- NCT01780038
- Testing
- Receipt of Genetic Results, No results given
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Kidney Transplantation, Vitamin D Deficiency
Vitamin D Replacement After Kidney Transplant
Vitamin D deficiency accelerates vascular risk progression after kidney transplant.
- Trial name
- NCT00748618
- Testing
- Standard vitamin D3 treatment, High dose vitamin D3 treatment
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- University of Nebraska
Stroke
Effects of Biofeedback on Walking Speed Post-stroke
Stroke is the leading cause of serious long-term disability in the United States. Walking speed is related to stroke severity and how well someone can return to community life.
- Trial name
- NCT05420857
- Testing
- Overground Visual Biofeeback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Nebraska
Chronic Heart Failure
Health Behavior-Related Outcomes With Diaphragmatic Breathing Retraining in Heart Failure Patients
The purpose of this study is to provide information on how the practicing of deep breathing ("DBR" - diaphragmatic breathing re-training) may improve the health outcomes and likelihood of heart failure patients to engage in…
- Trial name
- NCT01886391
- Testing
- Diaphragmatic Breathing Retraining
- Sponsor
- University of Nebraska
CMV Viral Loads in Seropositive Renal Transplant Recipients
Study of CMV in Kidney Transplant Recipients
Using novel CYTOF technology to measure a wide array of innate and adaptive cell proportions and cytokine levels, we plan a pilot study in old (>/=60 years) and young (20-40 years) renal transplant recipients who are…
- Trial name
- NCT02061215
- Testing
- CMV viral load
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Stress Echocardiography
Use of Reactivated DEFINITY or LUMASON in Patients Undergoing Rest or Stress Echocardiography
Use of Reactivated DEFINITY® in or LUMASON Patients Undergoing Rest or Stress Echo Purpose of the study: Each patient undergoing a rest or stress echocardiogram uses a full vial of DEFINITY® or LUMASON contrast agent.
- Trial name
- NCT02950493
- Testing
- perflutren lipid microsphere
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Exercise Training
Impact of Muscle Temperature on Muscle Growth and Breakdown: Cooling During Resistance Training
The purpose of this study is to examine the effect of human skeletal muscle temperature during resistance exercise on myogenic and proteolytic signaling.
- Trial name
- NCT05302791
- Testing
- Muscle Cooling, Resistance Exercise
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Sjogren-Larsson Syndrome (SLS)
Sjogren-Larsson Syndrome: Natural History, Clinical Variation and Evaluation of Biochemical Markers
Sjogren-Larsson syndrome (SLS) is a rare genetic disease in which patients typically exhibit ichthyosis (dry, scaly skin), intellectual disability, spasticity, seizures and a distinctive maculopathy.
- Trial name
- SLS (NCT01971957)
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Nebraska
Coronary Artery Disease, Myocardial Perfusion Abnormalities
Regadenoson Real Time Perfusion Imaging Trial-Optison
The purpose if this study is to examine how effective Regadenoson is in detecting coronary artery disease during a stress echocardiogram when Optison is administered.
- Trial name
- NCT01489176
- Testing
- Regadenoson; Optison
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- University of Nebraska
Chronic Disease
Home Based Care Transitions Tailored by Cognition and Patient Activation
There is overwhelming evidence that patients with multiple chronic illnesses need better self-management skills. Discharge from the hospital may not be the most opportune time to be teaching patients these self-management skills.
- Trial name
- NCT02045147
- Testing
- Grp 1a Low Cognition, Low Activation Intervention, Grp 2a Low Cognition, High Activation Intervention, Grp 3a Normal Cognition, Low Activation Intervention
- Where
- United States
- Volunteers
- 263 people
- Sponsor
- University of Nebraska