Clinical trials: sponsored by University of Nottingham
Glycemic Response to Feeding in Healthy Participants
White Rice and Effect of Gellan Gum on Glucose Responses by MRI
Rice is a staple food for over half the world's population. High consumption of white rice has been linked with high obesity and increased risk for type 2 diabetes.
- Trial name
- WIGG (NCT05080400)
- Testing
- White rice, Gellan gum
- Where
- United Kingdom
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Primary Raynaud Phenomenon
Cocoa Flavanol Supplementation in Raynaud's Phenomenon
The study aims to investigate the effect that supplementing the diet with cocoa flavanols has on vasospasm symptoms and temperature regulation in women with primary Raynaud's phenomenon (PRP).
- Trial name
- NCT03815162
- Testing
- High Flavanol Cocoa extract, Alkalised cocoa
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Clostridium Difficile Infection
Rifaximin for Preventing Relapse of Clostridium Associated Diarrhoea
Clostridium difficile associated diarrhoea is an important cause of morbidity in patients treated with antibiotics, especially in hospital. Clinical relapse occurs after up to 30% of initially successful treatments for colitis.
- Trial name
- RAPID (NCT01670149)
- Testing
- Rifaximin
- Where
- United Kingdom
- Volunteers
- 151 people
- Sponsor
- University of Nottingham
Ataxia Telangiectasia
A National Retrospective Population Based Cohort Study of the Natural History of Ataxia Telangiectasia
This is a retrospective observational study of natural-history of ataxia-telangiectasia. Understanding the natural history and its variability is not only vital to planning effective patient-centred services, and counselling…
- Trial name
- N-HAT (NCT04991701)
- Where
- 2 sites in United Kingdom
- Volunteers
- 178 people
- Sponsor
- University of Nottingham
Vaccination, Infection
Flu and Mood in Older Adults
Randomised control trial comparing the effects of a standardised and individualised positive affect digital intervention versus usual care on mood and antibody responses to influenza vaccination in older adults.
- Trial name
- For-ME (NCT03956329)
- Testing
- Standardised Digital Intervention, Individualised Digital Intervention
- Where
- United Kingdom
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Covid19
Process Evaluation of a Residence-Based SARS-CoV-2 Testing Participation Pilot
Mixed-methods process evaluation of a residence-based asymptomatic SARS-CoV-2 testing participation pilot
- Trial name
- RB-TPP (NCT05045989)
- Testing
- Residence-based testing participation pilot (SARS-CoV-2 testing with relaxed social distancing restrictions)
- Where
- United Kingdom
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Osteoarthritis, Knee, Pain, Joint
Knee Pain Nurse Led Package of CareTrial
1. To develop a training package for nurse-led management of knee osteoarthritis (OA), incorporating information about OA and core non-pharmacologic and pharmacologic principles of management of OA as recommended in the National…
- Trial name
- Team-KP (NCT03670706)
- Testing
- Exercise, analgesic optimisation
- Where
- United Kingdom
- Volunteers
- 1,806 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
HIV
Test@Work Study: Evaluation of Attitudes and Uptake Within Employee Health Checks in the Construction Industry
This project is called Test@Work. In this project the investigators will offer general health checks and tailored health advice to up to 650 employees in the construction industry at sites across the East Midlands.
- Trial name
- Test@Work (NCT04292002)
- Testing
- Test@Work
- Where
- United Kingdom
- Volunteers
- 456 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Physical Activity
Digital Worksite Exercise Intervention in China: Outcome and Process Evaluation
The aim of the study is to evaluate the outcomes and processes of a video and web-based worksite exercise intervention for sedentary office workers in China.
- Trial name
- Move-It (NCT04038658)
- Testing
- Move-It
- Where
- United Kingdom
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Mental Health Wellness 1
Evaluation of Staff COVID-19 Wellbeing Centres in a Healthcare Workplace: COVID-WELL Study
Evaluation of a workplace intervention to implement supported wellbeing centres in a healthcare workplace during and after the COVID-19 pandemic.
- Trial name
- COVID-WELL (NCT04410016)
- Testing
- Staff Wellbeing Centres
- Where
- United Kingdom
- Volunteers
- 819 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Type 2 Diabetes, Physical Exercise
The Use of Short SMS Messaging With Type 2 Diabetes (T2DM)
Physical activity (PA) can play a vital and an independent role in type 2 diabetes (T2DM) management care. Health research studies have shown evidence that PA can improve glycaemic control and glucose levels.
- Trial name
- mHealth (NCT04243174)
- Testing
- SMS Messaging
- Where
- Saudi Arabia
- Volunteers
- 57 people
- Sponsor
- University of Nottingham
Psychological Wellbeing
COVID-19 Psychological Wellbeing for Healthcare Students
We have developed an online learning resource designed to support healthcare staff during and after the COVID-19 pandemic. This resource has been produced in anticipation of the psychological effect of working during this time.
- Trial name
- PoWerS (NCT04429828)
- Testing
- COVID-19 e-package: Psychological wellbeing for healthcare workers
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Acute Kidney Injury
Non-recovery of Kidney Function After AKI
One in five patients admitted to hospital suffer a sudden reduction in kidney function, termed acute kidney injury (AKI). Rather than kidney 'injury' being caused by physical trauma, the term describes reversible damage caused by…
- Trial name
- RECOVER-AKI (NCT05014022)
- Testing
- Multiparametric renal MRI
- Volunteers
- 50 people
- Sponsor
- University of Nottingham
Interstitial Lung Disease, Idiopathic Pulmonary Fibrosis
It's Not JUST Idiopathic Pulmonary Fibrosis Study
Study of progression of fibrosis in ILD
- Trial name
- INJUSTIS (NCT03670576)
- Testing
- Optional Bronchoscopy, Quality of Life Questionnaires, Blood Samples for Biomarkers
- Where
- 24 sites in United Kingdom
- Volunteers
- 250 people
- Sponsor
- University of Nottingham
Hearing Loss, Fatigue
Fatigue and Hearing Loss.
An intervention group and a control group will complete a battery of questionnaires at four time points to investigate the impact of first-ever hearing aid fitting on fatigue and associated variables.
- Trial name
- NCT04875117
- Testing
- Hearing aid
- Where
- 2 sites in United Kingdom
- Volunteers
- 129 people
- Sponsor
- University of Nottingham
Muscle Atrophy, Postoperative Complications
Postoperative Electrical Muscle Stimulation (POEMS)
Patients lose a significant amount of muscle following major abdominal surgery. This is partly due to a catabolic response to the surgical insult and inflammation, but is also probably due to a lack of muscle use secondary to…
- Trial name
- POEMS (NCT04199936)
- Testing
- Electrical Muscle stimulation
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Nottingham
Asthma
Asthma: Phenotyping EXacerbations
The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation.
- Trial name
- APEX (NCT04293588)
- Testing
- spirometry, FOT, Induced sputum, bloods, nasal brushes, nasal lavage, skin prick, throat swab
- Where
- United Kingdom
- Volunteers
- 200 people
- Sponsor
- University of Nottingham
ASTHMA
Asthma: Phenotyping Exacerbations 2
The main outcomes of this study are to establish a cohort of well-phenotyped asthma patients with a recent history of an exacerbation.
- Trial name
- APEX 2 (NCT04293445)
- Testing
- spirometry, FOT, Induced sputum, bloods, nasal brushes, nasal lavage, skin prick, throat swab
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Nottingham
Infant, Newborn, Pharmacoepidemiology
Commonly Used Medicines On Neonatal Units in the UK
This retrospective analysis of drug utilisation data aims to study the patterns of use of medicines in neonatal units in the UK from 2010 to 2017.
- Conditions
- Infant, Newborn, Pharmacoepidemiology, Intensive Care Units, Neonatal
- Trial name
- COMMON (NCT03773289)
- Testing
- No intervention
- Where
- United Kingdom
- Volunteers
- 642,729 people
- Sponsor
- University of Nottingham
Medication Errors
Process Evaluation of OptimiseRx and PINCER
This study aims to evaluate two interventions designed to make medication prescribing safer, OptimiseRx and PINCER, which are being used in general practices across England.
- Trial name
- NCT04766619
- Where
- 3 sites in United Kingdom
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Nottingham