Clinical trials: sponsored by University of Oklahoma
Hemoptysis
Urokinase Like Plasminogen Activator Levels in Patients Undergoing Bronchoscopy
Some of the risk factors for bleeding following bronchoscopy is having a malignancy or an immunocompromised state. The etiology of this remains uncertain.
- Trial name
- NCT00929565
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Oklahoma
Gastrointestinal Hemorrhage
Effect of Tranexamic Acid in Upper Gastrointestinal Bleeding
The investigators hypothesize that addition of Tranexamic acid, an antifibrinolytic agent, to conventional therapy will lead to an improved outcome characterized by lower transfusion requirements.
- Trial name
- NCT01005147
- Testing
- tranexamic acid
- Sponsor
- University of Oklahoma
Sepsis
Coagulation Factors, Cytokines and Tissue Injury Markers in Sepsis
In an effort to better understand the interaction between the different mediators, the investigators propose to examine the time course of mediators, the indexes of organ injury and the coagulation cascade.
- Trial name
- Histone (NCT01012115)
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Oklahoma
Vascular Access
Fluoroscopy Guided Femoral Arterial Access
The purpose of this study is to compare the use of fluoroscopic guidance, (a commonly used X-ray technique), with the traditional approach, (where the doctors feel for the strongest pulse), to obtain access to the blood vessel in…
- Trial name
- NCT00222430
- Testing
- Fluoroscopy, Active Comparator
- Where
- 2 sites in United States
- Volunteers
- 990 people
- Sponsor
- University of Oklahoma
Liver Cancer
A Retrospective Review of Malignant Liver Tumors
This study will review the treatment and outcomes of patients having primary and metastatic hepatic malignancies. Patients treated with surgical resection, percutaneous radiofrequency ablation (RFA), and transarterial…
- Trial name
- NCT00728650
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- University of Oklahoma
Colon Cancer
Reminding Patients of the Important of Colorectal Cancer Screening Results in Patient-Initiated Promoting Colorectal Cancer Screening Via Colonoscopy
Colorectal cancer is the third most common cancer diagnosed and third leading cause of cancer-related deaths in the United States for both men and women.
- Trial name
- NCT01526239
- Testing
- Colorectal cancer screening pamphlet
- Where
- United States
- Volunteers
- 274 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pain
Using Dexamethasone After Uvulopalatopharyngoplasty
This study looks at lessening the pain after a Uvulopalatopharyngoplasty (UPPP) surgery by using Dexamethasone (a corticosteroid).
- Trial name
- NCT00584168
- Testing
- Dexamethasone
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Mild Cognitive Impairment
MemoryXL Effects on Mild Cognitive Impairment Patients
A vitamin nutriceutical, Memory XL, has been shown to provide maintenance of cognitive status in mild, moderate, and severe Alzheimer's disease patients (2 publications by T. Shea).
- Trial name
- MemoryXL (NCT00903695)
- Testing
- Memory XL
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- University of Oklahoma
PreTerm Birth, PreTerm Neonate
Trial of Immediate vs. Delayed Cord Clamping in the Preterm Neonate
To determine the short and long term effects of placental transfusion at birth by milking and delayed cord clamping of the umbilical cord in neonates born between 24 weeks 0 days and 34 weeks 0 days weeks' gestation.
- Trial name
- NCT00579839
- Testing
- Delayed Cord Clamping, Immediate Cord Clamping
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Coronary Artery Disease, Chest Pain
The Effect of Clopidogrel on Coated-Platelets in Patients Undergoing Cardiac Catheterization
This study will explore the effect of clopidogrel on coated-platelets in patients who are given a loading dose before diagnostic catheterization or percutaneous coronary intervention.
- Trial name
- NCT00644657
- Testing
- Clopidogrel
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Oklahoma
Thrombocytopenia
Study of the Effect of Differing Platelet Transfusion Times in Neonates
To evaluate changes in platelet counts and hemodynamics between "rapid" and "long" platelet infusion groups.
- Trial name
- NCT00948792
- Testing
- Short platelet transfusion, Long platelet transfusion
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Oklahoma
Child Neglect
Effectiveness Trial for Project SafeCare for Child Neglect
The study is a field trial comparing the SafeCare family preservation model to a comparable usual care model for parents in child welfare. The study also compares two levels of service quality control.
- Trial name
- NCT01391754
- Testing
- SafeCare, In vivo coached quality control, Services As Usual
- Where
- 3 sites in United States
- Volunteers
- 2,175 people
- Sponsor
- University of Oklahoma
Nulliparous Women
Effects of Age on the Levator Ani Muscle of Nulliparous Women
The purpose of the study is to characterize the levator ani structures (pubovaginalis, puboperinealis, puboanalis, puborectalis, and the iliococcygeous) using 3-D ultrasonography in nulliparous women 21-70 years old.
- Trial name
- NCT00964145
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Hematological Neoplasms, Hematopoietic Stem Cell Transplantation
Reduced-Intensity Allogeneic Hematopoietic Stem Cell Transplantation for Malignant Hematological Diseases
To evaluate engraftment and toxicity of a reduced intensity preparative regimen for patients who receive a matched related or unrelated donor allogeneic stem cell transplant (ASCT) for malignant hematological diseases
- Trial name
- NCT00582894
- Testing
- Busulfex, Fludarabine, ALemtuzumab
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Oklahoma
Mucositis, Head and Neck Cancer
A Trial of Homeopathic Medication TRAUMEEL S for the Treatment of Radiation-Induced Mucositis
The specific aim of this study will be to determine the safety of TRAUMEEL S for mucositis in head and neck cancer patients undergoing radiation therapy.
- Trial name
- TRAUMEEL (NCT00584597)
- Testing
- Saline, Traumeel S
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Chronic Renal Failure
A Study of Cytokine and Inflammatory Markers in Patients With Chronic Renal Failure
We hope to study components within the blood that may predict success, failure or other associated complications in relation to the type of vascular access being used.
- Trial name
- NCT00565994
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Non-Hodgkin's Lymphoma
Assessment of Hematopoietic Recovery Following Chemotherapy for Non-Hodgkin's Lymphoma
A study to determine the accuracy of FLT-PET in quantifying tumor cell proliferation at the initial staging of patients with Non-Hodgkin's Lymphoma in comparison wit the "gold standard" FDG-PET.
- Trial name
- NCT00775957
- Testing
- FLT-PET scan, FDG-PET scan
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Oklahoma
Fall Prevention
The Effects of Lower Body Resistance Training on Balance and Fall Prevention in the Elderly
The aim of the study is to prevent falls related to poor lower body strength adn balance in the elderly.
- Trial name
- NCT01178970
- Testing
- Resistance training
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Severe, Profound Deafness
Balance in Children With Cochlear Implants
The purpose is to test the balance of children with unilateral,bilateral cochlear implants and patients having unilateral implants before,bilateral implants after surgery,using the Bruininks-Oseretsky Test 2nd ed.
- Trial name
- NCT00642343
- Testing
- Evaluation of motor proficiency skills., Evaluation of motor proficiency, Evaluation of motor proficiency.
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Oklahoma
Tonsillectomy, Children
Closure Method Study Following Tonsillectomy in Children
This is a children's study evaluating the effects of a tonsillectomy with tonsillar fossae closure compared to without closure of the operative wound.
- Trial name
- NCT00730340
- Testing
- Closure of the Tonsillar Fossa, Tonsillectomy with open fossa
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma