Clinical trials: sponsored by University of Pittsburgh
Pharmacogenetics, Pharmacogenomic Drug Interaction
An Evaluation of the Impact of Pharmacist Personalized Medication Reviews With and Without a Discussion of Pharmacogenomic Results in an Employee Health Program.
The goal of this prospective randomized clinical trial is to learn if a pharmacist-provided personalized medication review (PMR) that discusses pharmacogenomic test results will improve medication outcomes.
- Trial name
- MyPGx (NCT06660264)
- Testing
- Pharmacist Personalized Medication Review (PMR), Discussion of Pharmacogenomic results during the PMR
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- University of Pittsburgh
HIV Infections, Inflammation
Relationship of Inflammation and Pulmonary Function to Fungal Translocation in HIV
The investigator will study the origin of fungal translocation in HIV, its relationship to the mycobiome, and its relationship to lung function and inflammation.
- Conditions
- HIV Infections, Inflammation, COPD
- Trial name
- RIFFT (NCT05502653)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Pittsburgh
Bladder Cancer, Neurogenic Bladder Disorder
Use of Wearables Following Cystectomy- Part II
The goal of this observational study is to learn about the practical considerations for having health care providers respond in real-time to abnormalities detected remotely for patients recovering from cystectomy following…
- Conditions
- Bladder Cancer, Neurogenic Bladder Disorder, Cystectomy
- Trial name
- NCT07148765
- Testing
- Fitbit Sense 2, Smartphone application survey
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Pittsburgh
Abdominal Surgery
Pip Care to Improve Surgical Patient Outcomes
Pip Care is developing a personalized, interactive surgical journey platform with a live health coach that works directly with health systems to optimize the perioperative care process.
- Trial name
- NCT06661291
- Testing
- Pip Care Digital Health Platform, Standard of Care Protocol
- Where
- 8 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Pittsburgh
ADHD, Parenting
Moms Managing Attention-Deficit/Hyperactivity Disorder (ADHD) Study
The study will develop and test a behavioral program for pregnant individuals with Attention-Deficit/Hyperactivity Disorder (ADHD).
- Trial name
- MomMA (NCT06540547)
- Testing
- MomMA Intervention
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Pittsburgh
Suicidal Ideation, Suicide, Attempted
Reducing Suicide Ideation Among Young People
It is Cluster Randomized Control Trial research to examine feasibility and relevance of the modified tool Nae Disha for Life, which will incorporate suicide prevention and resilience to reduce suicide ideation among young people…
- Trial name
- NCT06474312
- Testing
- Nae Disha
- Where
- India
- Volunteers
- 363 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Speech Impairment, Speech Disorder
Voiceitt for People With Impairments in Speech
The primary objective of this pilot study is to evaluate the feasibility and preliminary effectiveness of the Voiceitt app in improving communication for individuals with speech impairments due to conditions such as cerebral…
- Trial name
- NCT06874322
- Testing
- Voiceitt
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Pittsburgh
Childhood Obesity, Evidence-Based Practice
Network-Based Support to Help Community Coalition Members Choose and Use Strategies to Improve Child Health
Community coalitions bring together residents and organizations to improve child health, but they may need support to identify and put research-supported strategies into practice.
- Conditions
- Childhood Obesity, Evidence-Based Practice, Food Systems, Food Policy
- Trial name
- NCT07804550
- Testing
- Catalyzing Communities, FICAS Implementation Intervention
- Where
- United States
- Volunteers
- 3,300 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Idiopathic Pulmonary Fibrosis
PaTH Clinical Data Research Network (CDRN) Idiopathic Pulmonary Fibrosis (IPF) Clinician Patient Partnership Cohort
The purpose of the PaTH Network IPF Clinician-Patient Partnership Cohort is to use clinical data from electronic health records (EHR) and patient reported outcomes (PRO) to answer questions of clinical importance to patients with…
- Trial name
- NCT02407431
- Where
- 5 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- University of Pittsburgh
Spinal Cord Injuries, Cerebral Palsy
Mobile Health Self-Management and Support System for Chronic and Complex Health Conditions
This study will assess the benefits of using mobile health system designed for individuals with chronic and complex health conditions (such as those with Spinal Cord Injury,Cerebral Palsy, Spina Bifida, and Traumatic Brain…
- Conditions
- Spinal Cord Injuries, Cerebral Palsy, Spinal Dysraphism, Brain Injuries
- Trial name
- NCT02592291
- Testing
- MHealth
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Sexual Violence, Drinking Heavy
Reducing Alcohol Involved Sexual Violence in Higher Education
This cluster-randomized controlled trial across 28+ college campuses focuses on undergraduate college students at elevated risk for sexual violence and hazardous drinking (i.e., students with prior history of sexual violence…
- Trial name
- RAISE (NCT05185440)
- Testing
- GIFTSS Training, Learning Collaborative, Provider Scripts
- Where
- United States
- Volunteers
- 2,400 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Violence in Adolescence, Racism
Forging Hopeful Futures to Reduce Youth Violence
This cluster-randomized community-partnered study will examine the effectiveness of a racial-, gender-, and economic-justice focused youth violence prevention program called Forging Hopeful Futures with youth ages 13-19.
- Conditions
- Violence in Adolescence, Racism, Adolescent Behavior, Coping Skills
- Trial name
- FHF (NCT05743478)
- Testing
- Forging Hopeful Futures, Wellness Check-ins
- Where
- 2 sites in United States
- Volunteers
- 542 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Prescribing Decisions, Diabetes
Optimizing Prescribing Decisions for Hospitalized Older Adults With Chronic Conditions
The goal of this pilot clinical trial is to learn if providing a clinical decision framework for managing older adults chronic conditions during hospitalization to inpatient clinicians improves clinicians' ability to…
- Conditions
- Prescribing Decisions, Diabetes, Multimorbidity, Hypertension
- Trial name
- NCT06605807
- Testing
- Clinical Decision Framework for Managing older adults' chronic conditions during hospitalization.
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of Pittsburgh
Sickle Cell Disease
Effect of MitoQ on Platelet Function and Reactive Oxygen Species Generation in Patients With Sickle Cell Anemia
MitoQ is commercially available as a dietary supplement and it has been tested as a potential drug in other diseases, but it has never been tested in patients with sickle cell disease.
- Trial name
- MitoQ (NCT04109820)
- Testing
- MitoQ
- Where
- 5 sites in United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Depression in Adolescence, Depression in Adults
Neuro-affective Response to Light in Depressed Adolescents and Young Adults
The goal of this neuroimaging pilot study is to understand developmental differences in the impact of therapeutic wavelength light (blue light) versus a non-therapeutic wavelength (red light) on emotional brain function in…
- Trial name
- NCT05712772
- Testing
- Blue Light, Red Light
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Obesity, Childhood, Binge Eating
Project REST: Regulation of Eating and Sleep Topography
Overweight/obesity and inadequate sleep are prevalent, and frequently co-occurring, health risks among children, both of which are associated with serious medical and psychosocial health complications including risk for…
- Conditions
- Obesity, Childhood, Binge Eating, Sleep, Self-regulation
- Trial name
- NCT04057716
- Testing
- Sleep restriction, Sleep extension
- Where
- 2 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Stuttering, Childhood
Speech Signals in Stuttering
The purpose of this research study is to understand how speech and language are processed in the brain. This study will provide information that may help with the understanding how speech and language are processed in children…
- Trial name
- NCT05668923
- Testing
- Speech sound stimulation
- Where
- 2 sites in United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pulmonary Fibrosis
Microarray Analysis of Gene Expression in Idiopathic Pulmonary Fibrosis (IPF)
This study is investigating the way the lung is damaged in a condition called pulmonary fibrosis. Research studies will be conducted on lung tissue obtained from an open lung biopsy performed by the subject's surgeon.
- Trial name
- MAA (NCT00258544)
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Pittsburgh
Pulmonary Fibrosis
Genetic Polymorphisms in Idiopathic Pulmonary Fibrosis (IPF)
The purposes of this study are: to determine if there are specific genetic traits that might explain why patients have developed pulmonary fibrosis; to determine if specific genetic traits account for differing patterns of…
- Trial name
- GP (NCT00258570)
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- University of Pittsburgh
Idiopathic Pulmonary Fibrosis
Genomic and Proteomic Analysis of Disease Progression in Idiopathic Pulmonary Fibrosis (IPF)
The purpose of the study is to identify genetic and biologic markers that may predict the loss of lung function due to idiopathic pulmonary fibrosis.
- Trial name
- GAP (NCT00373841)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Pittsburgh