Clinical trials: sponsored by University of Rochester
Hearing Loss, Sensorineural
Hearing Study: Sensitivity to Features of Speech Sounds
The purpose of this study is to better understand the sensitivity of listeners to the fast changes in frequency or amplitude of sounds that occur in speech.
- Trial name
- NCT03666676
- Testing
- Signal processing to improve intelligibility
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Discoid Lupus Erythematosus
Study of Ruxolitinib Cream for the Treatment of Discoid Lupus Erythematosus
The purpose of this study is to assess the potential efficacy of topical ruxolitinib for the treatment of discoid lupus erythematosus (DLE)
- Trial name
- NCT04908280
- Testing
- Ruxolitinib
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Breast Cancer
Development of a Personalized Discussion Prioritization Tool for Older Adults Considering Adjuvant Chemotherapy for Breast Cancer
The investigators have developed a Discussion Prioritization Tool (DPT) for older adults consider adjuvant chemotherapy that utilizes Conjoint Analysis (CA) methodology and the objective of the current study is to assess…
- Trial name
- NCT05073432
- Testing
- Experimental
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Rochester
Community Practice, Staff
Understanding the Impact of Drug Shortages on Oncology Care Delivery
This trial studies the impact of drug shortages on oncology care delivery. Gathering information about cancer drug shortages over time may help researchers improve access to drugs during times of shortages.
- Trial name
- NCT03953027
- Testing
- Survey Administration
- Where
- 6 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester NCORP Research Base
Exotropia
Evaluation of Exotropia After Patching the Eye or After Prism Adaptation
This study intends to determine the number and percent of subjects initially diagnosed with divergence excess exotropia which would be reclassified as simulated divergence excess exotropia if tested after 24 hours of monocular…
- Trial name
- DESDEE (NCT05242510)
- Testing
- Patching, Prism Adaptation
- Where
- 9 sites in United States, Canada and 3 more
- Volunteers
- 1 people
- Sponsor
- University of Rochester
Dysphagia
TTE and Dysphagia in Anterior Cervical Surgery
The purpose of this study is to evaluate if Tracheal Traction Exercises (TTE) performed prior to anterior cervical spine surgery can result in a decreased rate of dysphagia.
- Trial name
- NCT02326116
- Testing
- Trachael Preparation Education
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Rochester
Covid19, Cancer
Serologic Response to the SARS-CoV-2 (COVID-19) MRNA-1273 Vaccine in Select Subsets of Oncology Patients
To explore the immune response to the COVID-19 vaccine in cancer patients and compare to the general population.
- Trial name
- NCT04854980
- Testing
- Blood Sample
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Rochester
Urinary Calculi
SP TLF Versus Ho:YAG Laser
The investigators aim to compare the performance of the Super Pulse Thulium fiber laser (SP TFL) with that of the standard Holmium: Yttrium-Aluminium-Garnet (Ho:YAG) laser.
- Trial name
- NCT05048706
- Testing
- Laser lithotripsy (SP TLF), Laser lithotripsy (Ho:YAG)
- Where
- 2 sites in United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Huntington Disease, Chorea
Risperidone for the Treatment of Huntington's Disease Involuntary Movements
The purpose of this study is to assess the safety and benefit of risperidone for the treatment of chorea (involuntary movements) in Huntington's disease.
- Trial name
- NCT04201834
- Testing
- Risperidone, BioStamp nPoint device
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Rochester
Substance Use, Violence
Brief Intervention for Justice-Involved Substance Users
This is a randomized clinical trial to study ways of helping justice-involved people change to more healthy behavior.
- Trial name
- NCT03308877
- Testing
- BMI, Stadard Care (SC)
- Where
- 2 sites in United States
- Volunteers
- 132 people
- Sponsor
- University of Rochester
Basal Cell Carcinoma
Investigation of Standard Excision Surgical Margins Using Two Photon Fluorescence Microscopy
The goal of this clinical trial is to compare the use of two photon fluorescence microscopy for detecting residual basal cell carcinoma during standard local excision.
- Trial name
- NCT06473103
- Testing
- Two photon fluorescence microscopy imaging
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Rochester
Premature Birth
Is Milk Associated with Glycemia in the NICU
The purpose of this study is to determine if concentrations of hormones in prepared human milk (HM) feeds are associated with metabolic disturbances in the recipient premature infant.
- Trial name
- MAGIC (NCT05256927)
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Rochester
Psoriasis
Serum, Cellular and Imaging Markers of Arthritis in Psoriasis Patients
The events that underlie the conversion from Psoriasis to Psoriatic Arthritis (PsA) are not well understood. This conversion occurs 30% of the time within the first 10 years of psoriasis diagnosis.
- Trial name
- RRF (NCT02413801)
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Social Connectedness
Social-LEAF Life Enhancing Activities for Caregivers
This study examines a behavioral intervention to improve social connection and reduce loneliness for caregivers of a loved one with Dementia with Lewy Bodies (DLB).
- Trial name
- NCT05274074
- Testing
- Social LEAF
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Loneliness, Social Isolation
Engage Psychotherapy to Promote Connectedness in Caregivers
The Engage Coaching Project is a Stage 1 intervention development study. This study asks: "what behavioral strategies are needed to help socially disconnected caregivers with significant barriers to increasing connectedness?"…
- Conditions
- Loneliness, Social Isolation, Caregiver Burnout
- Trial name
- NCT04176601
- Testing
- Engage coaching
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Chronic Hand Dermatitis
Topical Ruxolitinib in Chronic Hand Dermatitis
This is an investigator-initiated, proof of concept, open study to assess efficacy of a topical Ruxolitinib in subjects with Chronic Hand Dermatitis (CHD).
- Trial name
- NCT05293717
- Testing
- Ruxolitinib
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Rochester
Opioid Use, Loneliness
The Association Between Loneliness and Substance Use
The proposed study will determine if cognitive behavioral therapy will help improve loneliness in people who use opioids.
- Trial name
- NCT04938492
- Testing
- Cognitive Behavioral Therapy for loneliness (CBT-L), Physical Health Education Training (PHET)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Rochester
Smoldering Multiple Myeloma
Selinexor for the Treatment of Intermediate and High-Risk Smoldering Multiple Myeloma
Selinexor is a drug that has been approved in the treatment of patients with symptomatic multiple myeloma. The standard of care for patients with Smoldering Multiple Myeloma remains observation, but there are numerous clinical…
- Trial name
- NCT05597345
- Testing
- Selinexor
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
Covid19
Testing for COVID-19 in High Risk Children With Intellectual and Developmental Disabilities (COV-IDD)
The purpose of this study is to understand how to prevent COVID-19 spread in a school like the Mary Cariola Center (MCC) in Rochester, NY by answering questions like these: how do activities in the school alter chances of…
- Trial name
- NCT04887129
- Testing
- COVID-19 RT-PCR test, COVID-19 Vaccine Education Campaign
- Where
- United States
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Fetal Alcohol Spectrum Disorders
Study of the Families Moving Forward Website Behavioral Intervention for Teachers of Students With Fetal Alcohol Spectrum Disorder
The purpose of this study is to find out if the FMF Connect Teacher Companion website is acceptable and usable by teachers. The FMF Connect Teacher Companion website is a website for teachers adapted from the Families Moving…
- Trial name
- NCT05986565
- Testing
- Families Moving Forward (FMF) Teacher adapted training
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Rochester