Clinical trials: sponsored by University of Rochester
Cervical Cancer
Promoting Cervical Cancer Screening for Emergency Department Patients
The purpose of this study is to learn methods to encourage women to get recommended cervical cancer screening. Cervical cancer screening is an important part of cervical cancer prevention.
- Trial name
- NCT03483610
- Testing
- Provider Referral, Text Messaging
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Rochester
Thrombocytopenia
Study of Avatrombopag for Temozolomide-induced Thrombocytopenia in Glioma (APATIT-G)
The purpose of this study is to determine if using avatrombopag in patients with thrombocytopenia due to temozolomide treatment can safely improve a patient's platelet count and allow the patient to complete the temozolomide…
- Trial name
- NCT04931849
- Testing
- Avatrombopag
- Where
- United States
- Sponsor
- University of Rochester
Immunization; Infection, Pregnancy Related
Increasing Influenza and Tdap Vaccination of Pregnant Women
Pregnant women who get influenza are more likely than non-pregnant women to have serious complications, including hospitalizations, death, preterm labor and premature birth.
- Trial name
- NCT04444518
- Testing
- VAX-MOM Intervention, Standard of Care
- Where
- United States
- Volunteers
- 12,760 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Mental Health Issue, Alcohol Use Disorder
Acceptability and Feasibility of Cognitive Behavioral Therapy for Treatment-Seeking (CBT-TS) With Deaf Individuals
The current study aims to assess the acceptability and feasibility of an adapted version of Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS) for use with signing Deaf adults.
- Conditions
- Mental Health Issue, Alcohol Use Disorder, Depression, Anxiety
- Trial name
- NCT05520190
- Testing
- Cognitive Behavioral Therapy for Treatment Seeking (CBT-TS)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Cancer
A Supportive Care Intervention for Older Caregivers of Older Adults with Advanced Cancer
This project assesses the feasibility of utilizing the geriatric assessment as a tool to identify distressed older caregivers of older adults with cancer.
- Trial name
- NCT05244915
- Testing
- Experimental (Delphi Surveys), Experimental (Focus Groups), Qualitative interviews
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Rochester
Insulin Resistance, Obesity
Studying Infant Nutrition and Blood Sugar
The purpose of this study is to learn about how breast milk from mothers with insulin-resistance may be different. Investigators are specifically studying insulin concentrations in breast milk.
- Trial name
- NCT03524469
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Breathing, Mouth, Lung Function Decreased
Evaluating the Use of a Device Called Impulse Oscillometry in Participants With Vocal Cord Disorders or Asthma
This study will determine if airway resistance to airflow and pressure, measured by Impulse Oscillometry, is impacted in subjects with vocal cord disorders and whether these measurements are different when compared to subjects…
- Conditions
- Breathing, Mouth, Lung Function Decreased, Vocal Cord Dysfunction, Laryngeal Obstruction
- Trial name
- NCT05246930
- Testing
- Impulse Oscillometer
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Meniere Disease
A Study of a Mastoid Device in Subjects With Ménière's Disease
The purpose of this study is to investigate the efficacy of a mastoid treatment device in patients with active Ménière's disease that is not controlled by traditional medical management
- Trial name
- NCT03520322
- Testing
- Mastoid Oscillator, Control Device
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Rochester
Focus Groups
COACH-Cog Intervention Adaptation Focus Groups
To gather key stakeholder input for feedback on the adaption of the COACH GA intervention (i.e., develop COACH-Cog) to enhance triadic communication among oncologists, care partners and patients with ADRD.
- Trial name
- NCT05775991
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Rochester
Atrial Fibrillation
Use of Dapagliflozin to Reduce Burden of Atrial Fibrillation in Patients Undergoing Catheter Ablation of Symptomatic Atrial Fibrillation
This is a multicenter trial to evaluate the impact of treatment with dapagliflozin versus placebo following catheter ablation of atrial fibrillation (AF) on the burden of AF during 6-12 months of follow-up.
- Trial name
- DAPA-AF (NCT04792190)
- Testing
- dapagliflozin
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Prostate Cancer
Enzalutamide & Dutasteride/Finasteride as 1st Line Treatment for Patients =/> 65 Years Old With Prostate Cancer.
Determine the effect of enzalutamide and dutasteride or finasteride on the time to prostatic-specific antigen level increase in patients age 65 or older.
- Trial name
- NCT02213107
- Testing
- Enzalutamide and Dutasteride or finasteride
- Where
- 2 sites in United States
- Volunteers
- 43 people
- Sponsor
- University of Rochester
Lung Cancer
Vinorelbine and Bevacizumab in Treating Older Patients With Stage III or Stage IV Non-Small Cell Lung Cancer
RATIONALE: Drugs used in chemotherapy, such as vinorelbine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.
- Trial name
- NCT00309998
- Testing
- bevacizumab, vinorelbine tartrate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Rochester
Vision Loss Partial, Vision; Loss, Both Eyes
Understanding Visual Processing After Occipital Stroke
The purpose of this study is to investigate how visual orientation discrimination and metacognition (i.e., perceptual confidence) are affected by occipital stroke that causes hemianopia and quadrantanopia in adults.
- Conditions
- Vision Loss Partial, Vision; Loss, Both Eyes, Hemianopia, Homonymous, Hemianopia
- Trial name
- NCT06352086
- Sponsor
- University of Rochester
Recurrent Prostate Cancer After Surgery
This Study is Evaluating a New Radiation Treatment Technique for Patients Who Have Had Prostate Cancer, Undergone Surgery for Cancer, and Then Have Evidence That Their Prostate Cancer Has Returned.
There is significant, proven use of radiation for recurrent prostate cancer after surgical resection. This treatment typically is delivered over seven and a half weeks of daily treatments, presenting a burden to patients and the…
- Trial name
- DASBRT-RPC (NCT05946824)
- Testing
- Daily-adaptive Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Fetal Alcohol Spectrum Disorders
Feasibility Study of the My Health Coach App for Adults With FASD
The purpose of this study is to test a new smartphone "app" for adults with fetal alcohol spectrum disorder (FASD). The app is called My Health Coach.
- Trial name
- NCT05604014
- Testing
- My Health Coach
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Rochester
Urogynecology
Robotic Urogynecological Surgery: Hospital Stay and Perioperative Complications
The purpose of this study is to assess length of hospital stay and perioperative complications of patients undergoing daVinci Robot-assisted sacrocolpopexy, during a one-year time period, who did not complete a questionnaire on…
- Trial name
- NCT01033786
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Acalabrutinib and High Frequency Low Dose Subcutaneous Rituximab in Patients With Previously Untreated Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma
The main purpose of this research study is to find out if the combination of acalabrutinib and high frequency low dose subcutaneous rituximab is safe and effective in patients who have previously untreated chronic lymphocytic…
- Trial name
- NCT03788291
- Testing
- Acalabrutinib, Rituximab
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Rochester
Pediatric Kidney Disease
Safety, Feasibility, and Tolerability of Sulforaphane in Children with Chronic Kidney Disease
This purpose of this study is to investigate potential new therapeutics in pediatric chronic kidney disease (CKD). The specific aims are to identify safe dosing and tolerability of sulforaphane (SFN) supplementation in children…
- Trial name
- NCT05653492
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Rochester
HIV, Cardiovascular Risk Factor
Translating the ABCS Into HIV Care
The overall objective of this project is to develop and rigorously test implementation strategies to address the gap in scientific knowledge of lower use of evidence-based interventions commonly referred to as the ABCS (aspirin…
- Trial name
- ABCSinHIV (NCT03902431)
- Testing
- ABCS training
- Where
- United States
- Volunteers
- 4,277 people
- Sponsor
- University of Rochester
Metastatic Colorectal Cancer
Regorafenib in Metastatic Colorectal Cancer
The purpose of the study is to measure high grade (3-5) toxicity of regorafenib and to monitor the impact of treatment with regorafenib on the quality of life in older adults with metastatic colorectal cancer.
- Trial name
- NCT02466009
- Testing
- Regorafenib
- Where
- 4 sites in United States
- Volunteers
- 27 people
- Sponsor
- University of Rochester