Clinical trials: sponsored by University of Rochester
Metastatic Breast Cancer, Breast Cancer Stage IV
A Whole-food, Plant-Based Nutrition Intervention in Women With Metastatic Breast Cancer
This research will examine the feasibility of conducting a strict whole-food, plant-based dietary intervention in women with stable metastatic breast cancer currently undergoing conventional treatments.
- Trial name
- NCT03045289
- Testing
- Plant-Based Diet
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Rochester
Acute Myelogenous Leukemia
Study of Decitabine in Combination With Sequential Rapamycin or Ribavirin in High Risk AML Patients
To evaluate the response to chemotherapy with the drug decitabine combined with rapamycin in the treatment of relapsed or refractory acute myeloid leukemia in patients of all ages, and in the treatment of newly diagnosed leukemia…
- Trial name
- AML (NCT02109744)
- Testing
- Decitabine
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Rochester
Dental Caries
Effects of Nystatin Suspension Oral Application on Oral Microbial Community
The purpose of this study is to examine the effect of a prescription mouth rinse (Nystatin),an FDA approved drug, on the different types of bacteria in the mouth.
- Trial name
- NCT04550546
- Testing
- Nystatin
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Postpartum Depression, Postpartum Anxiety
A Pilot Trial of the Reach Out, Stay Strong, Essentials for Mothers of Newborns (ROSE) Postpartum Depression Prevention Intervention in Pregnant Patients Admitted to Strong Hospital
This study is a pilot, single-center, randomized controlled trial. It will 1. determine feasibility and acceptability of an evidence-based intervention for prevention of postpartum depression with antepartum patients on a…
- Trial name
- NCT05225025
- Testing
- ROSE, Standard of Care
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester
Smoking Cessation
Latinos Kick Buts: Mobile Engagement and Cessation Support for Latino Smokers
Latino Kick Buts (LKB) is a smoking cessation treatment program available to patients identified as smokers at the University of Rochester Medical Center.
- Trial name
- NCT05278481
- Testing
- Reward Message with standard introduction, Reward Message with culturally tailored introduction, Threat/Self-efficacy with standard introduction
- Where
- United States
- Volunteers
- 408 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chronic Obstructive Pulmonary Disease
Residential Cleaning of Indoor Air to Protect COPD Patients
This study looks at whether air cleaning devices put in the bedroom and living room of your home could reduce the irritation of your lungs and body that is caused by indoor air pollution.
- Trial name
- CARE (NCT03750292)
- Testing
- HEPAirX air filter, control air filter
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Rochester
Neoplasm Metastasis
Study of Resection Combined With Stereotactic Radiosurgery for 1 to 3 Brain Metastases
This study is to look more closely at the tumor removed during your surgery, and to follow your condition after your treatment. The purpose of this study is to determine what side effects are common or more rare from this…
- Trial name
- NCT00904553
- Testing
- Novalis Shaped Beam Surgery
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Chronic Kidney Disease Stage 3B, Chronic Kidney Disease, Stage 4
Effects of Whole Food, Plant-Based Nutrition on Chronic Kidney Disease With Proteinuria
This study will test the hypothesis that lifestyle intervention consisting of a whole food, plant-based (WFPB) diet and group education will favorably impact outcomes germane to individuals with chronic kidney disease (CKD) stage…
- Conditions
- Chronic Kidney Disease Stage 3B, Chronic Kidney Disease, Stage 4, Proteinuria
- Trial name
- NCT04171778
- Testing
- whole food, plant-based diet
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Breast Cancer
Effects of High Dose Calcitriol in Breast Cancer Patients
This research will examine the effectiveness of calcitriol in treating bone loss in women who are about to begin treatment for breast cancer. Twenty-five (25) subjects are expected to take part in this study.
- Trial name
- NCT01293682
- Testing
- Calcitriol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Rochester
Urinary Incontinence, Overactive Bladder
Nerve Stimulation Using a TENS to Provide Pain Relief During Surgery for Overactive Bladder
This will be a double blind randomized control trial in men and women with urinary urge incontinence that are undergoing outpatient operative cystoscopy for Onabotulinumtoxin A chemo denervation as third line therapy for…
- Conditions
- Urinary Incontinence, Overactive Bladder, Pain, Acute
- Trial name
- TENSOB (NCT05330117)
- Testing
- TENS, Control TENS
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Long QT Syndrome
Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients
The purpose of this study is to determine whether late sodium channel blockade might be effective in shortening the QTc interval in various LQT3 mutations and be considered as a safe therapeutic option for LQT3 patients.
- Trial name
- NCT01648205
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Traumatic Pneumothorax
Duration of Chest Tube Suction in Traumatic Pneumothorax
The purpose of this pilot study is to determine whether chest tube suction duration, 24 hours vs 48 hours, prior to water seal affects outcome and length of stay after placement for traumatic pneumothorax.
- Trial name
- NCT04986527
- Testing
- Chest tube suction
- Where
- United States
- Sponsor
- University of Rochester
Diabetes Mellitus, Type 2, Insulin Resistance
Effects of a Plant-Based Diet on Insulin Requirements and Obesity Markers in Obese Adults With T2DM
This is a crossover study utilizing a Dietary Approaches to Stop Hypertension (DASH) diet and a whole-food, plant-based diet among subjects with type 2 diabetes who require insulin.
- Conditions
- Diabetes Mellitus, Type 2, Insulin Resistance, Obesity, Nutritional and Metabolic Disease
- Trial name
- NCT04048642
- Testing
- DASH, Whole-Food, Plant-Based
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
Pain
Utility of Pharmacogenomic Testing and Postoperative Dental Pain Outcomes
Opioid analgesics are the most common postoperative pain medications used among dentists in the United States.Although these medications are highly effective in the postoperative dental pain management, not all patients optimally…
- Trial name
- NCT02932579
- Testing
- Pharmacogenomic Testing, Ibuprofen, hydroxycontin/acetominophen
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Respiratory Tract Infection
Impact of Respiratory Pathogens in Infants
This clinical study will investigate the relationships between sequential respiratory viral infections, patterns of intestinal and respiratory bacterial colonization, and adaptive cellular immune phenotypes which are associated…
- Trial name
- NCT01789268
- Testing
- Respiratory Inductive Plethysmography
- Where
- United States
- Volunteers
- 267 people
- Sponsor
- University of Rochester
Heart Failure With Preserved Ejection Fraction
Radiofrequency (RF) Ablation for Atrial Fibrillation (AF) in Patients With Heart Failure With Preserved Ejection Fraction
The purpose of this study is to determine if patients who receive an early radiofrequency ablation will have fewer hospitalizations, unplanned office visits, and emergency room visits than those patients treated with medical…
- Trial name
- AF-HFpEF (NCT04327596)
- Testing
- RF ablation of AF using CARTO 3 and a Thermocool ST SF ablation catheter
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- University of Rochester
Systolic Heart Failure, Atrial Fibrillation (Permanent)
Junctional AV Ablation in CRT-D: JAVA-CRT
Cardiac resynchronization therapy (CRT) is a demonstrably effective device intervention for patients with heart failure with reduced ejection fraction and specific indication.
- Trial name
- NCT02946853
- Testing
- Atrioventricular junctional (AVJ) ablation, Cardiac resynchronization therapy - defibrillator
- Where
- 21 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Rochester
Neoplasms
Sexual & Gender Minority Competency in Oncology
This study is a single-arm, open-label trial of a sexual and gender minority (SGM) competence training program at Wilmot Cancer Institute (Wilmot) and its regional care locations (e.g., Wilmot Medical Oncology, Wilmot Radiation…
- Trial name
- NCT04198090
- Testing
- SGM Competency Training Program
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Corneal Dystrophy, Band-Shaped
A Pilot Study to Assess the Preliminary Efficacy of EDTA Eye Drops on Band Keratopathy
The objective of this study is to collect preliminary efficacy and safety data on the use of EDTA EYE Drops (EED) on subjects during an episode of band keratopathy (BK).
- Trial name
- NCT03985371
- Testing
- EDTA Eye Drops
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Influenza
Comparison of Three Licensed Influenza Vaccines
This study will evaluate in detail the way that the immune system responds to three different kinds of flu shots that are licensed in the United States.
- Trial name
- NCT03068949
- Testing
- FluBlok, Fluzone, FluCelVax
- Where
- United States
- Volunteers
- 413 people, healthy volunteers welcome
- Sponsor
- University of Rochester