Clinical trials: sponsored by University of Rochester
Heart Failure, Depression
Problem-solving to Improve Depressive Symptoms and Self- Care Among Recently Hospitalized Adults With Heart Failure
The purpose of this study is to examine the feasibility of providing a problem-solving therapy-based intervention to improve both depressive symptoms and heart failure self-care specifically after hospital discharge.
- Trial name
- NCT03606304
- Testing
- Problem-solving therapy
- Sponsor
- University of Rochester
Improve Parent Understanding of Research Permission
Improving Measurement Of Parents' Understanding Of Research Permission
Well-informed potential subjects are presumably better able to make autonomous decisions about the risks and benefits of participating in a research study than those in possession of less information.
- Trial name
- NCT01704560
- Testing
- Coversheet to Informed Consent
- Where
- 2 sites in United States
- Volunteers
- 32 people
- Sponsor
- University of Rochester
Fatigue
Pilot Study on Energy Therapy or Massage to Reduce Fatigue
The proposed study will assess whether either massage or an Integrative Medicine practice called Reiki can alleviate fatigue in subjects receiving hormonal treatments.
- Trial name
- NCT02758756
- Testing
- Massage, Reiki
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- University of Rochester
Aging, Social Isolation
HARP-Project 1 Cognitive Training
Emerging evidence from social neuroscience suggests that prefrontal cortex (PFC), insular and anterior cingulate cortex (ACC) regulate social and emotional responses to acute threats to social connectedness among young adults.
- Trial name
- NCT03293823
- Testing
- VSOP training, MLA control
- Where
- 4 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Juvenile Neuronal Ceroid Lipofuscinosis
Cellcept for Treatment of Juvenile Neuronal Ceroid Lipofuscinosis
The primary objective of this trial is to establish the safety and tolerability of short-term (8 weeks) administration of mycophenolate mofetil in ambulatory children with JNCL.
- Trial name
- JUMP (NCT01399047)
- Testing
- Mycophenolate mofetil
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
Breast Neoplasms, Bone and Bones
Calcitriol, Physical Activity, and Bone Health in Cancer Survivors
Both the calcitriol and exercise interventions are aimed at reducing fracture risk by maintaining proper bone density, thereby preventing osteoporotic/osteopenic conditions and increasing muscle mass.
- Trial name
- NCT00904033
- Testing
- Calcitriol, Exercise, Multivitamin
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Rochester
Depression, Hypertension
Chinese Older Adults-Collaboration in Health (COACH)Study
This study will see if education of village doctors and aging workers in identification and management of hypertension and depression, using standardized procedures,consultation with a psychiatrist as needed, and collaborations…
- Trial name
- COACH (NCT01938963)
- Testing
- Collaborations in Health (COACH)
- Where
- 7 sites in United States, China
- Volunteers
- 2,685 people
- Sponsor
- University of Rochester
Age-related Macular Degeneration
Macular Degeneration and Aging Study
The purpose of this randomized trial is to examine the effectiveness of a psycho-social "Preventive Problem Solving Intervention" on emotional well-being, change in future outlook, and vision functioning in 250 Age-related…
- Trial name
- MADAS (NCT02224963)
- Testing
- Preventive Problem-Solving Training, Life and Health Review
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- University of Rochester
Prostatic Neoplasms, Bone Mineral Density Quantitative Trait Locus 3
High-dose Vitamin D Supplementation for ADT-induced Side Effects
The purpose of this study is to test the efficacy of a high-dose vitamin D supplementation regimen in reducing androgen deprivation therapy (ADT)-related side effects in older prostate cancer patients on ADT.
- Trial name
- NCT02064946
- Testing
- vitamin D
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Rochester
HIV
Get Ready And Empowered About Treatment
The purpose of this study is to rigorously assess a program designed to empower patient living with HIV, to improve their health care and health, and to reduce disparities.
- Trial name
- GREAT (NCT02165735)
- Testing
- patient activation training, Usual care
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- University of Rochester
Prostate Disease
ConfirmMDx Assay in Multiparametric MRI (mpMRI) PIRADS Scored Lesions After a Negative MR/US Fusion Biopsy
The purpose of this study is to see if the ConfirmMDx assay is useful in finding prostate cancer in patients who are at increased risk for prostate cancer based on elevated PSA and prostate lesion identified on mpMRI.
- Trial name
- NCT03597386
- Where
- United States
- Sponsor
- University of Rochester
Atypical Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura
The Role of Microparticles as a Biomarker
The investigators propose to characterize MPs in aHUS and TTP both at the onset and throughout treatment. The investigators believe that the number, size, and cell origin of MPs will differ between these two diseases.
- Conditions
- Atypical Hemolytic Uremic Syndrome, Thrombotic Thrombocytopenic Purpura, Microparticles, Microangiopathic Hemolytic Anemia
- Trial name
- NCT02626663
- Where
- United States
- Sponsor
- University of Rochester
Chemotherapy Symptoms
Aromatherapy for Chemotherapy-induced Symptoms
The rationale behind the proposed study is to determine the initial effectiveness of aromatherapy in relief of commonly reported symptoms in cancer patients undergoing chemotherapy.
- Trial name
- NCT02670941
- Testing
- Ginger, Lavender, Orange
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Post-Operative Urinary Retention
Prophylactic Tamsulosin Use for Prevention of Post-Operative Urinary Retention
This randomized open-label study will be comprised of 2 cohorts: one control group and one treatment group. The trial will be conducted as an open label randomized trial to evaluate the efficacy of tamsulosin in the prevention of…
- Trial name
- NCT02684344
- Testing
- Tamsulosin, Education
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Rochester
Cancer
VOICE: Values and Options in Cancer Care
The purpose of this study is to determine whether a combined intervention for patients, caregivers and oncologists improves communication, quality of life, and quality of care.
- Trial name
- VOICE (NCT01485627)
- Testing
- Communication training and coaching
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- University of Rochester
Depression
Realizing Opportunities for Self Empowerment
The purpose of this study is to determine whether priority-based patient navigation will improve patient satisfaction, quality of life (QOL), and depression when compared to screening-and-referral for socioeconomically…
- Trial name
- ROSE (NCT02087956)
- Testing
- Navigation, Enhanced Screening and Referral
- Where
- United States
- Volunteers
- 223 people
- Sponsor
- University of Rochester
Autistic Disorder, Enuresis
Investigation of Teacher-Mediated Toilet Training Using a Manualized Moisture Alarm Intervention
The purpose of this pilot study is to compare an innovative toilet training strategy with a standard behavioral intervention in children with autism spectrum disorder (ASD), as implemented by teachers in the school setting.
- Trial name
- NCT02369445
- Testing
- Moisture Pager Intervention for Toilet Training, Standard of Care
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Urge Incontinence, Overactive Bladder
A Study of Transcutaneous Electrical Nerve Stimulation for Overactive Bladder
The purpose of the study is to compare patient centered- outcomes between Transcutaneous Electrical Nerve Stimulation (TENS) at three locations to treat urinary urge incontinence.
- Trial name
- NCT02922842
- Testing
- Transcutaneous Electrical Nerve Stimulation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Autism Spectrum Disorder
Development and Pilot Testing of the Students With Autism Accessing General Education (SAAGE) Model
Study personnel will use evidence based behavioral skills training procedures to coach educators to implement modules designed to increase the quality of educational services and access to inclusive settings in elementary school…
- Trial name
- SAAGE (NCT03573128)
- Testing
- Students with Autism Accessing General Education, Enhanced Services As Usual
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Rochester
Prostate Disease
4-aminopyridine Treatment for Nerve Injury From Radical Retro-Pubic Prostatectomy
The purpose of this study is to see if the study drug 4-aminopyridine (4-AP) can help speed up the recovery of peripheral nerve injury after prostatectomy.
- Trial name
- NCT03658408
- Testing
- 4-aminopyridine
- Where
- United States
- Sponsor
- University of Rochester