Clinical trials: sponsored by University of Rochester
Depression
Strong Connections
The purpose of this study is to compare two talking forms of therapy designed to help reduce depressive symptoms in teenagers: Interpersonal Psychotherapy for Adolescents and Treatment as Usual.
- Trial name
- NCT03308864
- Testing
- Interpersonal Psychotherapy for Adolescents, Treatment as usual
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Neoplasms, Metastatic
A Study For Using Radiosurgery On Limited Metastases
The standard therapy in cases such as yours is surgery, radiation therapy, chemotherapy or hormonal therapy alone or in combination.
- Trial name
- NCT00178399
- Testing
- Stereotactic Body Radiation Therapy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Rochester
Dry Eye, Sjogren's Disease
Multi-Colored Placido Disk Viability
The purpose of this study is to show that the multi-colored Placido Disk set-up can get reliable data over long time periods.
- Conditions
- Dry Eye, Sjogren's Disease, Healthy
- Trial name
- NCT02148497
- Testing
- Multi-colored Placido disk imaging
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Bladder Cancer
Enzalutamide for Bladder Cancer Chemoprevention
The purpose of this study is to examine the effect of androgen deprivation therapy through administration of enzalutamide on preventing bladder cancer recurrences in patients with non-muscle invasive bladder cancer (NMIBC).
- Trial name
- NCT02605863
- Testing
- Enzalutamide
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Rochester
Pediatric Asthma
School-Based Telemedicine Enhanced Asthma Management
This project aims to improve guideline-based asthma care using enhanced communication and screening tools, telemedicine and directly observed therapy of preventive medications in city schools.
- Trial name
- SB-TEAM (NCT01650844)
- Testing
- School-Based Telemedicine Enhanced Asthma Management, Enhanced Usual Care
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester
Palliative Care
Improving Palliative Care Through Teamwork
One in three Americans dies in a nursing home (NH) or in a hospital, shortly following transfer from a long-term care facility. The proportion of deaths occurring in NHs is projected to increase to 40% by 2020.
- Trial name
- IMPACTT (NCT01990742)
- Testing
- Palliative Care Team (PCTeam)
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Nausea
Reducing Up-set Stomach and Vomiting After Surgery Using Essential Oils
The purpose of this study is to determine if aromatherapy (essential oil) is effective at reducing up-set stomach and vomiting after surgery and in reducing the need for up-set stomach medications
- Trial name
- NCT03370328
- Testing
- Peppermint oil, Ginger oil
- Where
- United States
- Volunteers
- 143 people
- Sponsor
- University of Rochester
Dental Caries, Restorative Material
Evaluate the Effectiveness of an Experimental Urethane Dimethacrylate Resin Based Dental Composite Material
This double blind randomized controlled prospective clinical trial will compare the clinical success of two tooth colored resin composite dental filling materials - TPH3 (Dentsply Caulk) and an experimental urethane…
- Trial name
- NCT02018822
- Testing
- urethane dimethacrylate, TPH3, Esthet-X HD
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
Ranolazine Implantable Cardioverter-Defibrillator Trial
The purpose of the study is to see how effective a drug called ranolazine is in reducing the risk of ventricular arrhythmia and death in people with implantable cardioverter-defibrillators (ICDs).
- Conditions
- Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy, Heart Failure
- Trial name
- RAID (NCT01215253)
- Testing
- Ranolazine
- Where
- 90 sites in United States, Canada
- Volunteers
- 1,012 people
- Sponsor
- University of Rochester
Depression
Interpersonal Psychotherapy for Adolescent Girls
This study will evaluate the efficacy of Interpersonal Psychotherapy for Adolescents (IPT-A) for the treatment of depression and prevention of depression in maltreated and nonmaltreated girls between the ages of 13-15 years old.
- Trial name
- IPT (NCT01534377)
- Testing
- Interpersonal Psychotherapy for Adolescents, Enhanced Care
- Where
- United States
- Volunteers
- 328 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Blood Pressure, Hypertension
Blood Pressure (BP) Visit Intensification Study
Aim 1: The purpose of the study is to implement the Seventh Joint National Committee on the Diagnosis, Prevention and Treatment of Hypertension (JNC VII) recommendation for monthly visits for hypertensive patients with…
- Trial name
- NCT02164331
- Testing
- JNC guideline training
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Mindfulness, Stress Disorder, Posttraumatic
Effects of Mindfulness on PTSD
The purpose of this randomized control trial is to examine the effects of a Mindfulness-Based Stress Reduction (MBSR) program on women with posttraumatic stress disorder related to intimate partner violence.
- Trial name
- NCT03484390
- Testing
- Mindfulness-based stress reduction, Wellness Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Rochester
Acute Myeloid Leukemia
Pilot Study of Feasibility of Outpatient Daily High Dose Cytarabine as Consolidation Therapy for Older Patients With Acute Myeloid Leukemia (AML)
High-dose cytarabine (HiDAC) is considered a standard chemotherapy treatment for patients with acute myeloid leukemia. However, most patients receiving this therapy are required to be admitted to the hospital during their…
- Trial name
- NCT02101983
- Testing
- Cytosine Arabinoside
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Rochester
Nausea
Alternative Approaches for Nausea Control
216 Chemotherapy-naïve, female breast cancer patients about to begin chemotherapy and who expect to have nausea, will be entered.
- Trial name
- NCT01695993
- Testing
- Acupressure bands, Expectancy-neutral handout, Expectancy-neutral MP3
- Where
- 4 sites in United States
- Volunteers
- 242 people
- Sponsor
- University of Rochester
Myotonic Dystrophy
Clinical Efficacy Trial of Mexiletine for Myotonic Dystrophy Type 1
The purpose of this study is to investigate the effects of mexiletine treatment for 6 months on ambulation, myotonia, muscle function and strength, pain, gastrointestinal functioning, cardiac conduction, and quality of life in…
- Trial name
- NCT01406873
- Testing
- Mexiletine
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Cancer
A Geriatric Assessment Intervention for Older Cancer Patients Receiving Chemotherapy
The purpose of this study is to determine whether information regarding GA and GA-driven interventions improves outcomes in older cancer patients receiving first-line or second-line chemotherapy by comparing rates of chemotherapy…
- Trial name
- NCT01915056
- Testing
- GA-driven Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Rochester
Chronic Disease
Improving Communication About Patient Priorities in Multimorbidity
The goal of this study is to develop and test Customized Care, an intervention to help patients dealing with depression and/or anxiety in the context of multiple chronic conditions.
- Trial name
- ICOM-APP (NCT02100982)
- Testing
- Customized Care, Care As Usual
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Dry Eye Disease
Optical Coherence Tomography of Tear Film Dynamics In-Vivo
The purpose of this study is to evaluate a new instrument that takes digital images of tear film (a thin film that coats the eye that is made up of oil and water).
- Trial name
- NCT02554084
- Testing
- Optical Coherence Tomography
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Charcot Marie Tooth Disease
Mexiletine for Muscle Cramps in Charcot Marie Tooth Disease
Charcot Marie Tooth Disease is a family of inherited peripheral neuropathies, with over 70 causative genes identified to date.1-4 Muscle cramps are frequent in CMT, affecting up to 85% of patients with some subtypes of CMT.
- Trial name
- NCT02561702
- Testing
- Mexiletine
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Rochester
Communication
Social and Behavioral Influence (SBI)
The purpose of the study is to improve patient-physician communication and clinical decisions in the context of serious illness that may affect important clinical outcomes.
- Trial name
- SBI (NCT01501006)
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Rochester