Clinical trials: sponsored by University of Rochester
Chickenpox, Rubella
MMR and Varicella Vaccine in Premature Infants
This research is designed to address the question, "Does the relative deficit in vaccine immunogenicity in extremely premature infants persist beyond the first 6 months of life?" We propose to measure the immunogenicity of…
- Conditions
- Chickenpox, Rubella, Rubeola, Mumps
- Trial name
- NCT00156559
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Pain, Postoperative
Arthroscopic Anterior Cruciate Ligament Reconstruction: A Comparison of Three Catheter Placement Positions
This investigation will evaluate the subjective effect on postoperative pain of three catheter placements in the knee: 1. intraarticular infusion only, 2. patellar tendon harvest site only, 3.
- Trial name
- NCT00178178
- Testing
- Breg Pain Care 3000 Catheter, Bupivicaine 0.5%
- Where
- United States
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Low Risk (0-10% Chance) of Developing Cardiovascular Disease Within 10 Years Based on Risk Factors, Moderate Risk (10-20% Chance) of Developing Cardiovascular (Heart) Disease Within 10 Years Based on Risk Factors
Interactive Cholesterol Advisory Tool
The purpose of this study is to show that we can effectively deliver health information and education, online, via computer regarding cholesterol. This computer program is called the Interactive Cholesterol Advisory Tool (ICAT).
- Trial name
- ICAT (NCT01890031)
- Testing
- Interactive Cholesterol Advisory Tool, Study physician visits
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Respiratory Insufficiency
Music Therapy for Patients Being Weaned From Mechanical Ventilation
The purpose of the study is to determine whether Music Therapy interventions can be used as supportive therapy for patients undergoing weaning from mechanical ventilation.
- Trial name
- NCT00178139
- Testing
- Music Therapy
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- University of Rochester
Carcinoma, Non-Small-Cell Lung
Pulsed Paclitaxel And Daily Thoracic Radiotherapy For Inoperable (Stage I/II) Or Unresectable Lung Cancer
A treatment study is being conducted by the University of Rochester Cancer Center (URCC) in which patients with non-small cell lung cancer will be treated with radiation therapy and a drug called paclitaxel.
- Trial name
- NCT00178256
- Testing
- Paclitaxel, Radiation Therapy
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Rochester
Multiple Sclerosis
Placebo vs. Linoleic Acid Controlled Assessment of Treatment Efficacy in MS
Several investigations have suggested that polyunsaturated fatty acids may promote therapeutic effects in MS. This pilot study will determine whether omega-6 polyunsaturated fatty acids (PUFAs),in the form of linoleic acid,can…
- Trial name
- PLACATE-MS (NCT00638196)
- Testing
- Linoleic Acid/Oleic Acid
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Rochester
Lateral Ankle Sprain
Lateral Ankle Sprain Study
The purpose of this study is to compare the short term treatment outcome measures of the standard of care air cell stirrup brace to that of a high tide fracture boot in patients with lateral ankle sprains.
- Trial name
- NCT00761865
- Testing
- Air Cast Stirrup Brace & High Tide Fracture Boot
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Rochester
Aqueous Deficient Dry Eye, Meibomium Gland Dysfunction
Non-invasive Tear Film Dynamic Measurements in Normal, MGD and ADDE Subjects After Saline Instillation
Compare the objective tear film dynamic measurements in three different populations (MGD [Meibomium Gland Dysfunction], ADDE [Aqueous Deficient Dry Eye] and normal/control [non-dry eye]) and the subjective experience before and…
- Trial name
- NCT01128049
- Testing
- Subjective Questionnaire, Measurement with wavefront sensor (right eye, then left eye), Instill Saline Drop
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Non-Hodgkin's Lymphoma
Pilot Study of Bortezomib, Bendamustine and Rituximab on Non-Hodgkin's Lymphoma
The purpose of this study is to evaluate how non-Hodgkin's lymphoma that has not responded to, or that has returned after standard treatment, responds to bortezomib, rituximab and bendamustine, and also to see what effects this…
- Trial name
- BVR (NCT00547534)
- Testing
- bortezomib, bendamustine, rituximab
- Where
- 3 sites in United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Brain Neoplasm
Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury
Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment of tumors with X-rays. This study is related to understanding the side effects of radiation treatment for brain tumors.
- Trial name
- NCT00178295
- Testing
- Radiation Therapy
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Rochester
Chronic Pain
Open-Label Trial Comparing Oxycodone Medications
The investigators hypothesize that subjects will have greater pain relief when taking IR-oxycodone compared with ER-oxycodone for several reasons.
- Trial name
- OUTCOMES (NCT01162304)
- Testing
- Extended Release Oxycodone, Immediate Release Oxycodone
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Rochester
Neuropathic Pain, Chronic Pain
Trial of Analgesia With Lidocaine or Extended-release Oxycodone for Neuropathic Pain Treatment in Multiple Sclerosis
This study will determine whether treatment with an extended-release opioid or topical lidocaine is effective in relieving distal symmetric lower extremity burning pain associated with multiple sclerosis (MS).
- Conditions
- Neuropathic Pain, Chronic Pain, Multiple Sclerosis
- Trial name
- NCT00414453
- Testing
- Lidocaine patch 5%, Extended-release oxycodone
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
Congenital Heart Disease
Transfusion Strategies in Pediatric Cardiothoracic Surgery
The purpose of this study is to determine the best red blood cell(hemoglobin) level for infants and children following surgical repair of particular heart defects.
- Trial name
- NCT00350220
- Testing
- transfusion strategy, Low Hb transfusion group
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Depression, Medication Administered in Error
Screening and Interventions in an Acute Care Setting
The purpose of this study is to: 1) evaluate the reliability and validity of EMS screening for depression and cognitive impairment and 2) to develop a pilot ED intervention program to address the needs of older adults found to be…
- Conditions
- Depression, Medication Administered in Error, Cognitive Impairment
- Trial name
- NCT00545155
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Rochester
Nausea
Acupressure and Relaxation for Nausea Control
This study hypothesizes that patients receiving efficacy enhancing information about the acupressure bands will expect less treatment-related nausea, which will subsequently result in less treatment-related nausea compared to…
- Trial name
- NCT00243269
- Testing
- Acupressure expectancy enhancement
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- University of Rochester
Stress, Cancer
Maternal Problem-Solving in Childhood Cancer
The purpose of this study is to help mothers of children with cancer to cope more effectively by increasing their problem-solving skills.
- Trial name
- NCT00234793
- Testing
- Problem-Solving Skills Training
- Where
- 4 sites in United States
- Volunteers
- 433 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Depression, Anxiety
Epidemiology of Depression, Anxiety, and Cognitive Impairment
Many older adults have undetected health problems and lack basic prevention measures. Failure to identify and treat these conditions can lead to unnecessary morbidity and mortality and a decreased quality of life.
- Conditions
- Depression, Anxiety, Cognitive Impairment
- Trial name
- NCT00717041
- Where
- United States
- Volunteers
- 1,206 people
- Sponsor
- University of Rochester
Cancer, Brain Tumor
Comparison of Educational Services and Outcomes for Patients Treated for Childhood Cancer
The purpose of the study is to evaluate some educational outcomes of children treated for childhood cancer.
- Trial name
- NCT00178386
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of Rochester
Traumatic Brain Injury
S-100B as Pre-Head CT Scan Screening Test After Mild Traumatic Brain Injury
The purpose of the study is to determine if a specific blood protein, S-100B, can help predict who will have a traumatic abnormality on head CT scan after a concussion.
- Trial name
- NCT00717301
- Where
- 6 sites in United States
- Volunteers
- 1,252 people
- Sponsor
- University of Rochester
Delirium, Post-Operative States
Namenda to Prevent Post-Operative Delirium
Post Operative Delirium is a common and serious risk of surgery. Delirium, when it occurs is associated with an increased risk of mortality, increase length of stay, and more adverse outcomes in general, including increased risk…
- Trial name
- NCT00303433
- Testing
- Namenda
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester