Clinical trials: sponsored by University of Rochester
Increased Drug Resistance
The Effects of Omega-3 Fatty Acids on Aspirin Resistance
The purpose of this study is to determine if omega-3 fatty acids enhance the antiplatelet effects of aspirin.
- Trial name
- NCT00771914
- Testing
- Aspirin, Lovaza, Both Aspirin and Lovaza
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Parkinson Disease
NINDS Parkinson's Disease Neuroprotection Trial of CoQ10 and GPI 1485
The goal of this study is to assess the impact of CoQ10 and GPI 1485 on the progression of Parkinson's disease, in order to determine whether it is reasonable to proceed with further study of either of these agents.
- Trial name
- NCT00076492
- Testing
- CoQ10, GPI 1485
- Where
- United States
- Volunteers
- 195 people
- Sponsor
- University of Rochester
Insomnia, Pain
Treatment of Insomnia Secondary to Chronic Pain
Several studies have shown that behavioral therapy for chronic pain can be beneficial for chronic pain and that behavioral therapy for insomnia can be beneficial for insomnia.
- Trial name
- NCT00127790
- Testing
- CBT for Insomnia (CBT-I), CBT for Pain (CBT-P)
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester
Primary Insomnia
The Psychoneuroimmunology of Insomnia
Chronic insomnia affects approximately 8-9% of the population. The prevalence of this disorder rises dramatically across the lifespan, especially so in women.
- Trial name
- NCT00680771
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Rochester
HIV Infections
Comparing Raltegravir Genital Tract Distribution in HIV-infected Men and Women
The purpose of this research study is to determine how much raltegravir gets into the male and female genital tract.
- Trial name
- NCT00745368
- Testing
- Raltegravir
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Rochester
Acute Myeloid Leukemia
A Study of Decitabine in Combination With Escalating Doses of Rapamycin in Patients With Relapsed or Refractory Acute Myeloid Leukemia
The purpose of this study is to determine the safety and feasibility of the combination of decitabine given at a fixed dose with escalating doses of rapamycin in patients with relapsed or refractory acute myeloid leukemia.
- Trial name
- NCT00861874
- Testing
- Decitabine, Rapamycin
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Rochester
Labor, Premature
Vaginal Progesterone as a Treatment for Women Active Preterm Labor
The purpose of this study is to compare how well vaginal progesterone works delaying the time to delivery in women with preterm labor compared to placebo.
- Trial name
- VagPro (NCT01206998)
- Testing
- Vaginal progesterone gel
- Where
- United States
- Sponsor
- University of Rochester
Urinary Retention, Neurogenic Bladder
Self Management in Urinary Catheter Users
Learning to self-manage urine flow may help people prevent or minimize persistent complications from long-term indwelling urethral or suprapubic catheters.
- Trial name
- NCT00883220
- Testing
- Self-management of urinary catheter
- Where
- 2 sites in United States
- Volunteers
- 202 people
- Sponsor
- University of Rochester
HIV Infection, Sexually Transmitted Diseases
Maintaining HIV Prevention Gains in Female Adolescents
In this study, an intervention is tested that is designed to reduced risky sexual behaviors in adolescent females. Study design: randomized, controlled study participants: 640 girls aged 15-19 years old length of follow-up: 1…
- Trial name
- NCT00161343
- Testing
- Health Improvement Project for Teens on HIV Prevention
- Where
- United States
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Huntington's Disease
Safety and Tolerability Study of Phenylbutyrate in Huntington's Disease (PHEND-HD)
The purpose of this study is to evaluate the safety, tolerability and clinical impact of 15-grams daily of sodium phenylbutyrate (phenylbutyrate) in Huntington's disease and to lay the groundwork for possible subsequent trials…
- Trial name
- NCT00212316
- Testing
- sodium phenylbutyrate
- Where
- 8 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Breast Cancer
Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients
Ionizing radiation is a toxic agent and widely accepted form of treatment for various types of cancer. Despite advances in medical technology, radiation therapy still causes severe early and late skin effects.
- Trial name
- NCT01042938
- Testing
- Curcumin C3 Complex
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Rochester
Myotonic Dystrophy
Effects of SomatoKine (Iplex)Recombinant Human Insulin-like Growth Factor-1/Recombinant Human Insulin-like Growth Factor-binding Protein-3 (rhIGF-I/rhIGFBP-3) in Myotonic Dystrophy Type 1 (DM1)
The aim of this study is to investigate the safety and feasibility of daily subcutaneous injections of recombinant IGF1 complexed with IGF binding protein 3 (SomatoKine-INSMED) as a treatment for muscle wasting and weakness in…
- Trial name
- NCT00233519
- Testing
- SomatoKine/IPLEX
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Acute Illness
Improving Outcomes of Hospitalized Elders and Caregivers
In this study, an intervention is tested that is designed to improve the outcomes of hospitalized elders and family caregivers. Study design: randomized, controlled study participants: 280 family caregivers aged 21 or above…
- Trial name
- NCT00178412
- Testing
- Care Project for Hospitalized Elders & Family Caregivers, Comparison Group
- Where
- United States
- Volunteers
- 421 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Pelvic Organ Prolapse
Outcomes and Patient Satisfaction After Colpocleisis for Pelvic Organ Prolapse
The purpose of this study is to evaluate the long-term success rate of the colpocleisis procedure and its effect on quality of life in women who have this surgery.
- Trial name
- NCT00714155
- Testing
- Questionnaires, Physical Examination
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Obesity, Cardiovascular Diseases
Workplace-Sponsored Program to Reduce Obesity
The purpose of this study is to design a comprehensive nutrition and physical activity strategy to gain a broad understanding of the social and cultural role of food and physical activity among workers.
- Trial name
- NCT00123513
- Testing
- Diet, Exercise, Environment
- Where
- United States
- Volunteers
- 3,938 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Postpartum Depression
Perinatal Depression Treatment in a Pediatric Setting- Pilot Phase
The purpose of this project is to test whether a new model of collaborative care depression treatment adapted to the needs and preferences of low-income, urban mothers with perinatal depression and to a pediatric clinic setting…
- Trial name
- MITT (NCT00804739)
- Testing
- Mother-Infant Treatment Team
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Rochester
Alzheimer's Disease, Psychomotor Agitation
Escitalopram Treatment of Patients With Agitated Dementia
The purpose of this study is to determine the safety and efficacy of escitalopram (Lexapro) using 10 or 20 mg daily in patients with Alzheimer's disease who are also experiencing agitation.
- Trial name
- NCT00260624
- Testing
- Escitalopram (Lexapro)
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of Rochester
Transfusion
Use of Cell Salvage Post-operatively in Infants to Decrease Use of Allogeneic Blood Product Transfusions
Transfusion of washed intra-operative cell salvage post-operatively in the PCICU can be performed safely without increased risk of bleeding or release of inflammatory mediators.
- Trial name
- cell salvage (NCT01211366)
- Testing
- Cell Saver RBCs, Conventional volume infusion
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- University of Rochester
Andersen-Tawil Syndrome
Effect of Potassium and Acetazolamide on People With Andersen-Tawil Syndrome
Andersen-Tawil Syndrome (ATS) is a rare genetic disorder that causes episodes of muscle weakness, potentially life-threatening changes in heart rhythm, and skeletal developmental abnormalities.
- Trial name
- NCT00839501
- Testing
- Potassium, Acetazolamide
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Rochester
Fatigue
A Randomized Study of Polarity or Massage Therapy to Reduce Fatigue in Breast Cancer Patients During Radiation Therapy
This research study is being conducted to compare the effectiveness of two types of complimentary medicine treatments to see if they will reduce the fatigue experienced by breast cancer patients receiving radiation therapy.
- Trial name
- NCT00288795
- Testing
- Massage Therapy, Polarity Therapy
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Rochester