Clinical trials: sponsored by University of Rochester
Rett Syndrome
Auditory EEG and Behavioral Assessments in Individuals With Rett Syndrome
This observational research study is designed to learn more about how the brain processes sound in individuals with Rett syndrome.
- Trial name
- NCT07569445
- Testing
- Electroencephalogram (EEG) Recording
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Chronic Kidney Diseases
Chronic Kidney Disease-Education (CKD-EDU)
The investigators are conducting a study to see which program better helps older patients with kidney disease choose their treatment.
- Trial name
- CKD-EDU (NCT06410144)
- Testing
- Program A, Program B
- Where
- 5 sites in United States
- Volunteers
- 326 people
- Sponsor
- University of Rochester
Smoking History, Current Smoker
Increasing Lung Cancer Screening Among Emergency Department Patients - LCS R01
This randomized clinical trial evaluates the effectiveness of text messaging and facilitated referral strategies to increase lung cancer screening uptake among emergency department patients who meet lung cancer screening…
- Conditions
- Smoking History, Current Smoker, Lung Cancer Screening
- Trial name
- NCT07566221
- Testing
- Basic Referral, Facilitated Referral, Text Messaging
- Volunteers
- 1,036 people
- Sponsor
- University of Rochester
Screening Compliance, Lung Cancer (Diagnosis)
Increasing Lung Cancer Screening Uptake Among Emergency Department Patients
The objective of the proposed clinical trial is to determine if we can increase LCS among ED patients using a combination of facilitated referral to an LCS program plus text message reminders to get screened.
- Conditions
- Screening Compliance, Lung Cancer (Diagnosis), Lung Cancer Diagnosis, Lung Cancer
- Trial name
- NCT07287085
- Testing
- Facilitated referral and text messaging, Basic Referral (enhanced control arm)
- Where
- United States
- Volunteers
- 349 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Asthma in Children
Telehealth-Enhanced Asthma Care for Home After the Emergency Room
The investigators propose a randomized controlled trial of Telehealth-Enhanced Asthma Care for Home After the Emergency Room (TEACH-ER) vs. enhanced care (EC).
- Trial name
- TEACH-ER (NCT05844891)
- Testing
- Telehealth-Enhanced Asthma Care for Home After the Emergency Room (TEACH-ER), Enhanced Care (EC)
- Where
- United States
- Volunteers
- 430 people
- Sponsor
- University of Rochester
HPV, HPV Associated Cancers
Emergency Department-based Cervical Cancer Screening Through Self-sampling
This project will compare the uptake of cervical cancer screening through ED HPV sampling among patients presenting to the ED.
- Conditions
- HPV, HPV Associated Cancers, HPV Cancers, Cervical Cancer Screening
- Trial name
- NCT07345897
- Testing
- Cervical Cancer Screening
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Fetal Alcohol Spectrum Disorders
Thrive Person-Centered Planning Program for Young Adults With Fetal Alcohol Spectrum Disorders
This study evaluates the Thrive person centered planning program for young adults with fetal alcohol spectrum disorders. Participants are randomized to either an immediate start or delayed start group for the psychoeducation…
- Trial name
- NCT07016009
- Testing
- Thrive Program
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Caregivers of People With Dementia
A Cultural Adaptation of the Caregiver TLC Psychoeducational Program to Support Latino Caregivers (CUIDANDO JUNTOS)
This study will test the feasibility and influence of a behavioral intervention called "Cuidando Juntos" in Latino caregivers of people with dementia.
- Trial name
- CuidandoJuntos (NCT06394388)
- Testing
- Cuidando juntos
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Rochester
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Comparing Brief Behavioral Therapy (BBT-CI) and Healthy Eating Education Learning (HEAL) for Cancer-Related Sleep Problems While Receiving Cancer Treatment
This phase III trial compares BBT-CI to HEAL for the reduction of insomnia in patients with stage I-IV cancer who are receiving cancer treatment. Cancer treatment can cause side effects such as sleep problems.
- Trial name
- BBT-II (NCT04829539)
- Testing
- Behavioral Intervention, Electronic Health Record Review, Quality-of-Life Assessment
- Where
- 153 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Rochester NCORP Research Base
Cancer Related Cognitive Difficulties, Breast Cancer Female
Effects of Chemotherapy on Cognitive Function in Breast Cancer Patients & Non-Cancer Control Subjects With Optional Sub-Study Research Brain MRI
Study is enrolling newly diagnosed breast cancer patients about to start chemotherapy and age-matched control participants. The investigator is trying to better understand the prevalence of cognitive difficulties in cancer…
- Trial name
- NCT03137095
- Testing
- Cognitive testing, Research Brain MRI
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Acute Myeloid Leukemia
A Patient-centered Communication Tool (UR-GOAL) for Older Patients With Acute Myeloid Leukemia, Their Caregivers, and Their Oncologists
This is a pilot study to evaluate the usability and feasibility of a patient-centered communication tool (University of Rochester-Geriatric Oncology Assessment for acute myeloid Leukemia or UR-GOAL) among 15 older patients with…
- Trial name
- UR-GOAL 1 (NCT04625413)
- Testing
- Behavioral: UR-GOAL communication tool
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Rochester
Insomnia
Comparing Virtual Yoga to Standard Care on Insomnia Among Cancer Survivors
This feasibility phase II randomized controlled trial examines the preliminary efficacy of our standardized four-week YOCAS©® (Yoga for Cancer Survivors) intervention that is delivered virtually on insomnia and sleep quality in…
- Trial name
- NCT04458194
- Testing
- Standard Care, YOCAS©® yoga
- Where
- 2 sites in United States
- Volunteers
- 42 people
- Sponsor
- University of Rochester
Breathing, Lung Function Decreased
Body Composition Related Evaluation of Airway Tone and Hyper-rEactivity Using Oscillometry
This study will determine if airway resistance to airflow and pressure, measured by Oscillometry, is associated with abnormal findings on methacholine challenge testing and whether these findings are associated with body habitus,
- Conditions
- Breathing, Lung Function Decreased, Asthma (Diagnosis), Obesity
- Trial name
- BREATH-OSC (NCT07356310)
- Testing
- Oscillometer
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Mild Cognitive Impairment (MCI), Memory Disorders, Age Related
Music for the Mind Study
The goal of this pilot clinical trial is to learn if older adults with mild cognitive impairment (MCI) find two music programs equally acceptable.
- Conditions
- Mild Cognitive Impairment (MCI), Memory Disorders, Age Related, Memory Decline
- Trial name
- M4M (NCT06866327)
- Testing
- Piano lessons, Music Lessons
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Rochester
PTSD, Trauma
Multiphase Optimization Strategy (MOST) for Treating Pediatric Post-traumatic Stress Disorder (PTSD)
The goal of this clinical trial is to test the extent to which different treatment components work to improve pediatric post-traumatic stress disorder (PTSD). It will also provide evidence for how these components work.
- Conditions
- PTSD, Trauma, Pediatric ALL
- Trial name
- MOST for PTSD (NCT06956781)
- Testing
- Emotion Regulation, Exposure, Cognitive Processing
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Rochester
Acute Pulmonary Embolism
Incorporating Healthy Living Strategies to Aid in Recovery After Acute Pulmonary Embolism
The purpose of the ERAsE-PE study is to determine whether two different healthy living strategies (along with anticoagulation) might aid in recovery after a patient is hospitalized for pulmonary embolism.
- Trial name
- ERASE-PE (NCT06784492)
- Testing
- Healthy Living Intervention-1, Healthy Living Intervention-2
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Rochester
Breast Cancer Metastatic, Endometrial Cancer Stage IV
Plant-Based Nutrition for Breast or Endometrial Cancer
This is a randomized controlled trial of a whole food, plant-based (WFPB) dietary intervention among women with metastatic breast or endometrial cancer.
- Trial name
- BEND-MBEC (NCT07189702)
- Testing
- Control, Whole Food, Plant-Based Diet with Behavioral Education and Support
- Volunteers
- 60 people
- Sponsor
- University of Rochester
Abscess
Safety and Feasibility Study of Methylene Blue Photodynamic Therapy to Sterilize Deep Tissue Abscess Cavities
The objectives of this Phase 1 study are to evaluate the safety and feasibility of methylene-blue-mediated photodynamic therapy (MB-PDT) performed at the time of abscess drainage to treat deep tissue abscesses.
- Trial name
- NCT02240498
- Testing
- Methylene Blue, 20% I.V. Fat Emulsion, Insertion of optical fiber
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Rochester
Basal Cell Carcinoma
Investigation of Mohs Surgical Margins Using Two Photon Microscopy
The goal of this clinical trial is to compare the use of two photon fluorescence microscopy for detecting residual basal cell carcinoma during Mohs surgery.
- Trial name
- NCT05814900
- Testing
- Two photon microscopy imaging
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- University of Rochester
Myotonic Dystrophy Type 1 (DM1), DM1
Remote Assessments and Genetic Determinants of Myotonic Dystrophy
The goal of this observational study, conducted in participants' homes and requiring no travel to a study site, is to better understand disease variability in people with myotonic dystrophy type 1 (DM1) and to identify effective…
- Trial name
- REACH-DM (NCT07505342)
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Rochester