Clinical trials: sponsored by University of Rochester
Acute Myeloid Leukemia, Myelodysplastic Syndromes
A Telehealth Advance Care Planning Intervention for Older Patients With Acute Myeloid Leukemia and Myelodysplastic Syndrome
This is a pilot study to evaluate the usability and feasibility of a telehealth-delivered advance care planning intervention among 20 older patients with acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS).
- Trial name
- SICG (NCT04745676)
- Testing
- Telehealth, Control
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Rochester
Hematologic Malignancies
An Inpatient Advance Care Planning Intervention for Older Patients With Hematologic Malignancies
This is a pilot study to assess the preliminary efficacy of an inpatient advance care planning intervention on outcomes in older patients with hematologic malignancies
- Trial name
- Inpatient SICP (NCT05433090)
- Testing
- Inpatient serious illness care program
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Rochester
Intervention
A Mobile Health Exercise Intervention for Older Patients With Myeloid Neoplasms
This is a pilot study to evaluate the feasibility of a mobile health exercise intervention (GO-EXCAP Mobile App) over 7 weeks in 25 patients with myeloid neoplasms receiving hypomethylating agents.
- Trial name
- GO-EXCAP (NCT04035499)
- Testing
- GO-EXCAP Mobile App
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Rochester
Pediatric Asthma
High Flow Nasal Cannula Rates in Pediatric Asthma
This is a randomized, open-label, 3-armed feasibility trial will examine conventional oxygen therapy (COT) vs high flow nasal cannula at 4L/min flow vs HFNC at 2L/kg/min flow (max 60L/min) in moderate to severe pediatric asthma…
- Trial name
- NCT06379607
- Testing
- "High Flow" High Flow Nasal Cannula, "Low Flow" High Flow Nasal Cannula
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Cancer, Dementia
Enhancing Triadic Communication About Cognition for Older Adults With Alzheimer's Disease or Related Dementias Facing a Cancer Management Decision
Building upon prior work, the investigator team developed a communication intervention for older adults with ADRD who are considering a decision about cancer management (adapted intervention: COACH-Cog).
- Trial name
- COACH-Cog (NCT06313853)
- Testing
- COACH-Cog
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Rochester
Atrial Fibrillation (AF)
Comparative Effectiveness of Different Techniques for Repeat Ablation of Atrial Fibrillation
Atrial fibrillation (AF) is the most common type of irregular heartbeat doctors see. People with AF sometimes have a procedure called an ablation to help get their heart back into a normal rhythm.
- Trial name
- REPEAT-AF (NCT06988202)
- Testing
- Pulmonary Vein Isolation (PVI) without Left Atrial Posterior Wall Isolation (PWI), Pulmonary Vein Isolation (PVI) with Left Atrial Posterior Wall Isolation (PWI)
- Where
- United States
- Volunteers
- 630 people
- Sponsor
- University of Rochester
Atrial Fibrillation, Heart Failure
Insertable Cardiac Monitor for Primary Atrial Fibrillation Detection in High-Risk Heart Failure Patients
Patients with heart failure (HF) represent a large population of patients who are at high risk for complications related to undiagnosed atrial fibrillation (AF).
- Trial name
- ASSERT-AF (NCT04818645)
- Testing
- ASSERT Insertable Cardiac Monitor, Conventional Management and monitoring
- Where
- United States
- Volunteers
- 477 people
- Sponsor
- University of Rochester
Suicide Prevention, Suicide
Career Enhancement Training Study Delivered Across Career Phases
This trial tests the effectiveness of the Wingman-Connect Program delivered by USAF personnel on individual suicide risk. Randomization will be among classes at Initial Technical Training, in which 396 classes of USAF personnel…
- Trial name
- NCT05967364
- Testing
- Wingman-Connect, Stress Management
- Where
- United States
- Volunteers
- 2,970 people
- Sponsor
- University of Rochester
Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
An Observational Research Study for Cancer Patients on Immune Checkpoint Inhibitors, DiRECT Study
This study compares treatment outcomes between patients of African American/Black (AA) ancestry and European American/White (EA) ancestry currently receiving immune checkpoint inhibitor treatment.
- Trial name
- DiRECT (NCT05364086)
- Testing
- Biospecimen Collection, Electronic Health Record Review, Interview
- Where
- 259 sites in United States
- Volunteers
- 2,100 people
- Sponsor
- University of Rochester NCORP Research Base
Parkinson Disease Dementia, Parkinson Disease
Community Outreach for Palliative Engagement -- Parkinson Disease
The purpose of this study is to learn more about the effectiveness of palliative care training for community physicians and telemedicine support services for patients and carepartners with Parkinson's disease and Lewy Body…
- Conditions
- Parkinson Disease Dementia, Parkinson Disease, Parkinson's Disease and Parkinsonism, Lewy Body Parkinsonism
- Trial name
- COPE-PD (NCT05222386)
- Testing
- Parkinson Disease Standard Care, Online Community-Supported Palliative Care
- Where
- United States
- Volunteers
- 632 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Parkinson's Disease (PD)
Cross-sectional Study of Vitamin B6 in Parkinson's Disease
The purpose of this study is to estimate the prevalence of abnormal serum levels of vitamin B6, and the associations of those levels with demographic and clinical variables in a randomly selected sample of people living with…
- Trial name
- NCT07430722
- Where
- United States
- Volunteers
- 288 people
- Sponsor
- University of Rochester
Mild Cognitive Impairment
Applying a Person-Centered Approach to Enhance Cognitive Training in Senior Living Community Residents With Mild Cognitive Impairment
Computerized cognitive interventions (CCIs) have been increasingly widely implemented among older adults with mild cognitive impairment (MCI).
- Trial name
- CogT-PACT (NCT03292705)
- Testing
- PEP, CCI
- Where
- 2 sites in United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Lung Cancer Screening
Advancing Lung Cancer Screening One Text at a Time
The purpose of this study is to assess the feasibility, acceptability, and preliminary impact of text messaging to promote lung cancer screening.
- Trial name
- NCT07227480
- Testing
- Text messaging program, Educational material
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Rochester
Fetal Alcohol Spectrum Disorders
My Health Coach App RCT
The goal of this clinical trial is to learn if the My Health Coach app helps adults with fetal alcohol spectrum disorders (FASD).
- Trial name
- NCT06638463
- Testing
- My Health Coach app
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Rochester
Burns
Understanding Coagulation and Inflammation in Burns
The purpose of this study is to understand what happens to platelets and blood clotting factors in burn patients over time. This study will also examine the role of microparticles (MPs), nanoparticles (NPs), and micro RNA in…
- Trial name
- NCT03077269
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Clinician Communication Skills Training
SOPHIE: Standardized Online Patient for Healthcare Interaction Education
This study evaluated an online simulation based educational program designed to improve clinician communication skills. Participants were clinicians and clinical trainees who completed simulated patient interactions and…
- Trial name
- SOPHIE (NCT07409233)
- Testing
- SOPHIE Simulation Training, Control Educational Materials
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Abscess
Efficacy of Methylene Blue Photodynamic Therapy for Treatment of Deep Tissue Abscesses
The objective of this Phase 2 study is to evaluate the efficacy of methylene blue photodynamic therapy (MB-PDT) performed at the time of percutaneous abscess drainage for disinfection of deep tissue abscesses.
- Trial name
- NCT06052956
- Testing
- Methylene Blue, Lipid Emulsion, Insertion of optical fiber
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Right Bundle-Branch Block, Heart Failure
His-Bundle Corrective Pacing in Heart Failure
The investigators aim to prospectively evaluate the efficacy and mechanism of benefit of His-bundle pacing enhanced cardiac resynchronization therapy (His-CRT) vs.
- Conditions
- Right Bundle-Branch Block, Heart Failure, His-bundle Pacing, Cardiac Resynchronization Therapy
- Trial name
- HIS-CRT (NCT05265520)
- Testing
- His-CRT implantation, BIV-CRT implantation
- Where
- 14 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Rochester
Post-partum Depression
Treatment of Post-partum Depression Using an Behavioral Intervention Called ROSE (Reach Out, Stay Strong, Essentials for Mothers of Newborns) Delivered Using an Electronic App
A randomized trial of pregnant people at risk for postpartum depression comparing the InBloom app (n = 76) to ROSE (n = 76; weekly scheduled group), and two control groups.
- Trial name
- NCT05518162
- Testing
- InBloom, ROSE
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- University of Rochester
Suicide Prevention
Population Impact of Wingman-Connect Implemented by the US Air Force
This study involves collection of implementation data and analysis of USAF de-identified administrative data on base-level suicide attempt rates following US Air Force (USAF) delivery of Wingman-Connect training at 8 operational…
- Trial name
- NCT05973942
- Testing
- Wingman-Connect
- Where
- United States
- Volunteers
- 17,400 people
- Sponsor
- University of Rochester