Clinical trials: sponsored by University of Southern Denmark
Rupture of Anterior Cruciate Ligament, Muscle Degeneration
Can Targeted Exercise Improve Knee Strength Following ACLR (RATE)
Anterior cruciate ligament reconstruction (ACLR) is high volume surgery, carried out in about 2800 patients annually in Denmark per year.
- Conditions
- Rupture of Anterior Cruciate Ligament, Muscle Degeneration, Gait, Unsteady
- Trial name
- RATE (NCT02939677)
- Testing
- Targeted exercise
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- University of Southern Denmark
Thyroidectomy
The Impact of Post-thyroidectomy Neck Stretching Exercises on Improving Short Term Quality of Life
The project deals with patients undergoing surgery in the neck due to benign tumor in the thyroid gland in order to remove pressure symptoms. The background of the project is a recent series of studies (Sorensen, Watt et al.
- Trial name
- NCT04645056
- Testing
- Stretching and Mobility exercises for neck and shoulder
- Where
- Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Children, Overweight
The Odense Overweight Intervention Study
Strong and consistent evidence have shown that overweight, including obesity, is an important risk factor for the development of cardiovascular disease (CVD) in adults.
- Conditions
- Children, Overweight, Obesity, Metabolic Syndrome
- Trial name
- OOIS (NCT01574352)
- Testing
- Small intervention, Intervention camp
- Where
- 2 sites in Denmark
- Volunteers
- 115 people
- Sponsor
- University of Southern Denmark
Anal Fistulas
Aspiration Treatment of Perianal Abscess
The purpose of this study is to compare aspiration and oral antibiotics with surgical incision in the treatment of perianal abscesses in terms of recurrence and subsequent fistula formation.
- Trial name
- NCT02585141
- Testing
- MEDIPLAST® (aspiration), incision, Clindamycin
- Where
- Denmark
- Volunteers
- 111 people
- Sponsor
- University of Southern Denmark
Musculoskeletal Disorders, Whiplash
Value-based Cognitive Behavioral Therapy for Prevention of Chronic Whiplash-associated Disorders
The purpose of this study is to determine whether a specifically tailored value-based cognitive behavioural therapy program (V-CBT) is able to prevent the development of persistent disability, pain, and psychological distress if…
- Trial name
- NCT02251028
- Testing
- Value-based cognitive-behavioral therapy
- Where
- Denmark
- Volunteers
- 92 people
- Sponsor
- University of Southern Denmark
Autoimmune Diseases, Inflammatory Bowel Diseases
Chronic Inflammatory Disease, Lifestyle and Risk of Disease
Chronic inflammatory diseases (CID) - including inflammatory bowel diseases (Crohn's disease and ulcerative colitis), rheumatic conditions (rheumatoid arthritis, axial spondyloarthritis, psoriatic arthritis), inflammatory skin…
- Conditions
- Autoimmune Diseases, Inflammatory Bowel Diseases, Crohn Disease (CD), Ulcerative Colitis (UC)
- Trial name
- PROCID-DCH (NCT03456206)
- Testing
- Intake of red and processed meat and fibres, Lifestyle factors independently or combined
- Where
- Denmark
- Volunteers
- 57,053 people
- Sponsor
- University of Southern Denmark
Stress, Anxiety
The Wild Man Programme - a Nature-based Rehabilitation Enhancing Quality of Life for Men on Long-term Sick Leave
The aim of the present study is to examine whether the nature based 'Wild man Programme' can help to increase quality of life among men on sick leave compared to treatment as usual.
- Conditions
- Stress, Anxiety, Depression, Cardiac Disease
- Trial name
- NCT04073524
- Testing
- Nature-Body-Mind-Community, Treatment as usual
- Where
- Denmark
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
GERD, Reflux, Gastroesophageal
Applying Long-term Follow-up to Improve Patient Selection in Laparoscopic Anti-reflux Surgery
Introduction Laparoscopic anti-reflux surgery is considered standard of care in surgical treatment of gastro-oesophageal reflux disease and is not without risks of adverse effects, most notably disruption of the fundoplication…
- Conditions
- GERD, Reflux, Gastroesophageal, Surgery
- Trial name
- NCT03959020
- Testing
- Anti-reflux surgery
- Where
- Denmark
- Volunteers
- 520 people
- Sponsor
- University of Southern Denmark
Cancer
Partnership-Project - Reinforcing Partnership Between Cancer Patient, General Practitioner and Oncologist During Chemotherapy
Background International guidelines underline the importance of strengthening the coordination and continuity of cancer care. The different roles of general practitioners and oncologists with regard to treatment, follow-up and…
- Trial name
- PSP (NCT02716168)
- Testing
- Shared video consultation between patient, general practitioner and oncologist
- Where
- Denmark
- Volunteers
- 281 people
- Sponsor
- University of Southern Denmark
Presbycusis, Bilateral
Impact of Hearing Aid Technology on Self-reported Outcomes
The study aims to investigate if the level of hearing aid (HA) technology has an impact on self-reported outcomes in patients with presbycusis in terms of overall IOI-HA scores, Factor 1, Factor 2 scores, SSQ scores, and the SSQ…
- Trial name
- NCT04539847
- Testing
- High-end hearing aid, Basic hearing aid
- Volunteers
- 208 people
- Sponsor
- University of Southern Denmark
Preeclampsia
Predicting Late-onset Preeclampsia at 10-14 Weeks of Pregnancy
The aim of this study is to make it easier to predict late-onset preeclampsia at 11-14 weeks of pregnancy. This will be done by measuring certain proteins in the mother's blood together with obtaining the mother's medical…
- Trial name
- NCT04075708
- Where
- Denmark
- Volunteers
- 1,427 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Quality of Life
Quality of Life Among Acute Admitted Elderly
Elderly dependent on homecare, admitted acutely, are fragile. The aim of this study is to investigate the difference in the definition and rating of Quality of Life (QoL) among acute admitted elderly i) with and ii) without…
- Trial name
- NCT03762941
- Where
- Denmark
- Volunteers
- 406 people
- Sponsor
- University of Southern Denmark
GERD, Fundoplication
Utilization of Anti-reflux Treatment and Course of Illness Leading to Reoperation
The purpose of this study is to investigate course of illness leading to reoperation after primary anti-reflux surgery and investigate the utilization of anti-reflux treatment, both medical and surgical, in the period 2000-2017
- Trial name
- NCT03536169
- Where
- Denmark
- Volunteers
- 3,717 people
- Sponsor
- University of Southern Denmark
Gastroesophageal Reflux
Treatment of Newly Diagnosed Gastroesophageal Reflux Disease in a National Population-based Cohort
This study evaluates the treatment of newly diagnosed gastro-esophageal reflux disease in a Danish national cohort, comparing medical and surgical treatment.
- Trial name
- NCT03524781
- Where
- Denmark
- Volunteers
- 36,292 people
- Sponsor
- University of Southern Denmark
Organic Cation Transporter 1, Morphine
Genetic Variation in Organic Cation Transport 1 (OCT1) and Its Significance for Morphine Pharmacokinetics
The main objective of the trial is to investigate the effect of known genetic variants in organic cation transporter 1 (OCT1) on the effect of morphine after major surgery
- Trial name
- NCT03425084
- Testing
- Morphine
- Where
- 2 sites in Denmark
- Volunteers
- 86 people
- Sponsor
- University of Southern Denmark
Metformin, Organic Cation Transporter 1
Inter- and Intra-individual Variations in Metformin Pharmacokinetics - The Importance of Genes and Drug Interactions
The investigators aim to investigate the interindividual variation in metformin AUC in a large cohort of healthy volunteers after a single dose of metformin.
- Conditions
- Metformin, Organic Cation Transporter 1, Codeine
- Trial name
- NCT03335423
- Testing
- Oral metformin, Intravenous metformin, Oral codeine and oral metformin
- Where
- Denmark
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Physical Frailty
Protein and Exercise to Counteract Frailty in Older Adults
The purpose of this study is to determine the effects of interventions with high-protein diet alone or in combination with resistance training on muscle mechanical function (muscle power and strength), frailty status, functional…
- Trial name
- NCT03842579
- Testing
- Resistance training, High-protein diet, Recommendations
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- University of Southern Denmark
Mucus Colitis, Inflammation, Colon
The Impact of Red Meat and Whole-grains Intake on the Colonic Mucosal Barrier
This study evaluates the impact of red meat and whole-grain intake on the colonic mucosal barrier and the dietary impact of these groups on the induced low-grade inflammation
- Conditions
- Mucus Colitis, Inflammation, Colon, Dietary Exposure
- Trial name
- NCT04235348
- Where
- Denmark
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy
The Influence of High and Low Salt on Exosomes in the Urine
The hypothesis is that changes in the epithelial sodium channel (ENaC) in the kidney is reflected in urinary exosomes and that the amount of ENaC as well as the cleavage degree is upregulated in conditions with low salt.
- Trial name
- NCT02823613
- Testing
- High salt diet followed by low salt diet, Low salt diet followed by high salt diet
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Obstructive Sleep Apnoea (OSA)
Effect of Bariatric Surgery on Obstructive Sleep Apnea in a Danish Cohort
Studies have shown high prevalence (60-94%) of obstructive sleep apnoea (OSA) among patients undergoing bariatric surgery. Fifteen studies are published investigating the effect of bariatric surgery on OSA.
- Trial name
- NCT02012868
- Testing
- bariatric surgery
- Where
- Denmark
- Volunteers
- 56 people
- Sponsor
- University of Southern Denmark