Clinical trials: sponsored by University of Southern Denmark
Alcohol Abuse
Web-based Ultra-brief Intervention for Heavy Drinkers Trial
The purpose of the study is to determine whether a web-based ultra-brief intervention, consisting of personalized normative feedback or standardized self-help material, is effective in lowering self reported alcohol use in heavy…
- Trial name
- NCT00751985
- Testing
- Personalised normative feedback (PNF), Self-help material, Control
- Where
- Denmark
- Volunteers
- 1,380 people
- Sponsor
- University of Southern Denmark
Physical Activity
Internet-based Physical Activity Intervention
The purpose of this study is to determine whether access to a website with personalized feedback on physical activity level and suggestions to increase physical activity results in improvements in self-reported physical activity…
- Trial name
- NCT01295203
- Testing
- website assess
- Where
- 4 sites in Denmark
- Volunteers
- 12,287 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Metformin, Organic Cation Transporter 2
A Pharmacokinetic Evaluation of Metformin in Relation to the Polymorphism A270S in Healthy Caucasian Volunteers
The aim of the study is to evaluate the pharmacokinetics of metformin in healthy Caucasians volunteers with and without the polymorphism A270S in OCT2,thus the study hypothesis is that renal clearance of metformin is affected in…
- Conditions
- Metformin, Organic Cation Transporter 2, Polymorphism,Single Nucleotide
- Trial name
- NCT01237522
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Cytochrome P450 Phenotype and Genotype Metrics
Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes
The Cytochrome P450 enzymes are responsible for the metabolism of a wide range of drugs and other xenobiotics. Genetic variants of the encoding P450 genes have shown to influence the rate of metabolism of many clinically used…
- Trial name
- NCT00981929
- Testing
- Tramadol, Omeprazole, losartan, caffeine, Tramadol, omeprazole, losartan, caffeine
- Where
- Denmark
- Volunteers
- 412 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Physical Inactivity
The Effect After 12 Weeks of Having Received a Pedometer and a Pedometer Program on Physical Activity and Health
Physical activity is associated with a reduced risk of several chronic diseases in addition to all-cause mortality. Hence for public health purposes, knowledge of effective interventions to increase the physical activity level in…
- Trial name
- NCT01071811
- Testing
- Pedometer-based intervention
- Where
- 3 sites in Denmark
- Volunteers
- 668 people
- Sponsor
- University of Southern Denmark
Consequences for Nursing Home Residents and Staff of Integrating Reminiscence Into Daily Nursing Care.
Consequences From Use of Reminiscence: a Randomised Intervention Study in Ten Danish Nursing Homes
Reminiscence is the systematic use of memories and recollections to strengthen self-identity and self-worth. The study aim was to investigate the consequences for nursing home residents and staff of integrating reminiscence into…
- Trial name
- NCT00937885
- Testing
- Implementation of reminiscence
- Where
- Denmark
- Sponsor
- University of Southern Denmark
Depression, Pain
Paroxetines Effect on Tramadols Metabolism and Pharmakodynamics: a Dose Response Study
The purpose of the study is to examine the connection between the dose of paroxetine and the effect of paroxetine on tramadols metabolism and thereby the effect of tramadol on the median pupil size.
- Trial name
- NCT00785603
- Testing
- Paroxetine, Tramadol
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Frailty
Autonomy Among Physically Frail Older People in Nursing Homes
The purpose of this study is to assess the status of perceived autonomy and to evaluate the effectiveness of individually tailored programmes on perceived autonomy in physically frail older people living in nursing homes.
- Trial name
- NCT00783055
- Testing
- Individually tailored programmes
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- University of Southern Denmark
Healthy
Uptake of the Antifungal Miconazole and Effect on Estrogen Metabolizing Enzymes in Humans
The purpose of this study, is to study the uptake of the pharmaceutical antifungal miconazole when used as a vaginal suppository in young women.
- Trial name
- NCT00668538
- Testing
- Brentan (miconazole)
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Healthy
The Effect of Escitalopram on the Pharmacokinetics and Pharmacodynamics of Tramadol in Healthy Subjects
Escitalopram will be given to a panel of 16 healthy subject for 9 days. On the ninth day a single dose of tramadol is administered to the subjects and pharmacokinetic(PK) and pharmacodynamic(PD) measurements are done for the next…
- Trial name
- NCT00692263
- Testing
- escitalopram and tramadol
- Where
- Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Stroke, Myocardial Infarctions
Letigen® and Cardiovascular Morbidity
Letigen® was a combination drug containing ephedrine, an adrenergic agonist with lipolytic and appetite-inhibiting properties. The drug was used as adjuvant treatment of obesity from 1990 and up to 2002 when it was withdrawn from…
- Conditions
- Stroke, Myocardial Infarctions, Sudden Death
- Trial name
- NCT00692666
- Volunteers
- 300,000 people
- Sponsor
- University of Southern Denmark
Healthy
Pupillary Changes as a Potential Biomarker for Escitalopram in Relation to CYP2C19 Polymorphism
To study the impact of CYP2C19 polymorphism on escitalopram pharmacokinetics and pharmacodynamics measured as changes in pupil diameter
- Trial name
- NCT00397059
- Testing
- Escitalopram
- Where
- Denmark
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Physical Inactivity, Motivation
Evaluation of Effect of Exercise on Prescription - a Psychological Perspective
The purpose of this study is to evaluate the effect of a primary healthcare intervention called 'Exercise on Prescription' aimed at increasing level of physical activity and psychological parameters in a population of sedentary…
- Conditions
- Physical Inactivity, Motivation, Behavior Change
- Trial name
- EoP (NCT00594360)
- Testing
- Exercise on Prescription
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- University of Southern Denmark
Low Back Pain
Information or Physical Activity for Chronic LBP
The purpose of this study is to compare a specific fear-reducing information with symptom-based exercise
- Trial name
- NCT00410319
- Testing
- Fear-reducing Information, Symptom-based exercise
- Sponsor
- University of Southern Denmark
Metabolic Syndrome X, Diabetes Mellitus, Type 2
Evaluation of Effect of Exercise on Prescription
The purpose of this study is to evaluate the effect of a primary healthcare intervention called 'Exercise on Prescription' aimed at increasing level of physical activity in a population of sedentary patients with increased risk…
- Conditions
- Metabolic Syndrome X, Diabetes Mellitus, Type 2, Cardiovascular Diseases
- Trial name
- NCT00399997
- Testing
- Exercise on Prescription
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- University of Southern Denmark
Type 2 Diabetes Mellitus
Atorvastatin and Endothelial Function in Type 2 Diabetes Mellitus (ATTEND-Study)
The aim of this study is to examine the effect of intensive cholesterol lowering therapy and tight blood pressure (BP) regulation on endothelial function (inner cell layer of vessels that determines dilatation) in type 2 diabetic…
- Trial name
- NCT00124397
- Testing
- Atorvastatin
- Where
- Denmark
- Volunteers
- 186 people
- Sponsor
- University of Southern Denmark