Clinical trials: open to volunteers, sponsored by University of Thessaly
Obesity & Overweight, Vitamin D
Exercise Training and Vitamin D Metabolism
The prevalence of Vitamin D deficiency is significantly higher in adults with overweight/obesity compared to those with normal body mass index (BMI).
- Trial name
- Hybri-D (NCT07300332)
- Testing
- Exercise training, Control
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Acute Respiratory Distress Syndrome (ARDS)
Early Switch in Moderate ARDS
The optimal timing for transition from controlled to assisted mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) remains uncertain.
- Trial name
- SWITCH-ARDS (NCT07907276)
- Testing
- Protocolized Transition From Controlled to Assisted Mechanical Ventilation
- Volunteers
- 30 people
- Sponsor
- University of Thessaly
Chronic Musculoskeletal Pain
Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain
This randomized controlled trial aims to evaluate the effectiveness of the "Algo(S)Therapy" Pain Neuroscience Education (PNE) program in patients with chronic musculoskeletal pain.
- Trial name
- NCT07001449
- Testing
- Pain Neuroscience Education with Communication Training, Pain Neuroscience Education without Communication Training, Usual Physiotherapy Treatment
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University of Thessaly
Fibromyalgia
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Fibromyalgia (FMS) is characterized by chronic musculoskeletal pain, sleep disturbances, and fatigue. It is not entirely clear how Bcomplex vitamins affect the human pain system, while at the same time there have been approaches…
- Trial name
- NCT07863232
- Testing
- Melatonin 1mg and intravenous B-complex vitamin drip
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Weaning Mechanical Ventilation
External Validation of VVI
Failure of liberation from mechanical ventilation increases days spent being mechanically ventilated, the length of stay and the morbidity of patients.
- Trial name
- E-VVI (NCT07372664)
- Where
- 3 sites in Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Obesity
Chrono-Fasting in Overweight and Obese Adolescents
Childhood and adolescent obesity represents a major global public health concern, with a steadily increasing prevalence over recent decades, accompanied by a rise in metabolic disorders among younger populations.
- Trial name
- ChronoFasting (NCT07759414)
- Testing
- Early TRF, late TRF, Control
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- University of Thessaly
Performance Recovery, Exercise-induced Inflammation
S-Acetyl Glutathione and Performance Recovery in Soccer
Soccer players display elevated inflammatory and oxidative stress markers combined with reduced soccer specific performance over a 72-hour period.
- Conditions
- Performance Recovery, Exercise-induced Inflammation, Exercise-induced Oxidative Stress
- Trial name
- NCT07690124
- Testing
- 200 mg S-Acetyl Glutathione, 500 mg S-Acetyl Glutathione
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Metabolic Health, Mental Health
Health Benefits of Dance Exercise
In Greece, people of different age groups, including young children to older adults, participate in dance exercise training. Although it is well-known that regular participation in dancing is associated with benefits such as…
- Conditions
- Metabolic Health, Mental Health, Physical Performance
- Trial name
- NCT07615829
- Testing
- Exercise training, No exercise training
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations
Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair
This study will evaluate the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.
- Conditions
- Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation
- Trial name
- CoFA-TAAA (NCT06432387)
- Testing
- Patients undergoing complex thoraco-abdominal aortic aneurysm repair
- Where
- 2 sites in Greece
- Volunteers
- 58 people
- Sponsor
- University of Thessaly
Frailty Syndrome, Hip Fractures
Translation and Cultural Adaptation of the Groningen Frailty Indicator (GFI) in Patients With Hip Fracture
This study attempts to the translation and the cultural adaptation of the Groningen Frailty Indicator (GFI) questionnaire in the Greek population in patients suffering from hip fracture.
- Trial name
- Gr-GFI (NCT05091645)
- Testing
- GFI
- Where
- Greece
- Volunteers
- 89 people
- Sponsor
- University of Thessaly
Frailty, Hip Fracture
Frailty, Hip Fractures and Inflammatory Biomarkers
We ought to investigate if hip fracture patients suffering from frailty have higher inflammatory burden according to simple inflammatory biomarkers.
- Conditions
- Frailty, Hip Fracture, Inflammatory Biomarkers
- Trial name
- NCT06614478
- Where
- 2 sites in Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Cerebral Palsy (CP)
The Effectiveness of Neurodevelopmental Treatment (Bobath) and Functional Physiotherapy in Children With Cerebral Palsy.
Cerebral palsy is one of the most common causes of physical disability in childhood and is often associated with impaired trunk control, reduced upper limb strength, and limitations in functional mobility and daily activities.
- Trial name
- NCT07496151
- Testing
- Neurodevelopmental Treatment, Functional Physiotherapy
- Volunteers
- 40 people
- Sponsor
- University of Thessaly
Non-communicable Diseases (NCD), Addiction to Opioids
Systematic Examination of Health Inequalities: Documentation, Patterns, and Determinants
The existence of social inequalities is a major global issue and a salient challenge for the European Union. During COVID-19 pandemic, health disparities became more evident.
- Conditions
- Non-communicable Diseases (NCD), Addiction to Opioids, Incarceration, Opioid-use Disorders
- Trial name
- CHANCE (NCT07558187)
- Where
- 5 sites in Greece
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Inflammatory Joint Diseases, Rheumatoid Arthritis (RA)
Oxidative Stress in Autoimmune Rheumatic Diseases
Rheumatic diseases constitute a group of non-communicable diseases characterized by chronic inflammation. The most common autoimmune rheumatic diseases (ARDs) are rheumatoid arthritis, psoriatic arthritis, systemic lupus…
- Conditions
- Inflammatory Joint Diseases, Rheumatoid Arthritis (RA), Psoriatic Arthritis (PsA), Ankylosing Spondylitis (AS)
- Trial name
- REDOX-ARD (NCT07536529)
- Where
- Greece
- Volunteers
- 200 people
- Sponsor
- University of Thessaly
Skin Cancer, Heat Tolerance
Title: ICARUS - Psycho-physiological Profiling of Low and High Heat-resilient Individuals
The escalating environmental heat-stress associated with global warming is a societal challenge with large and potential harmful consequences for humans.
- Conditions
- Skin Cancer, Heat Tolerance, Heat-related Illness, Hyperthermia
- Trial name
- ICARUS (NCT07510061)
- Testing
- Controlled Heat and Ultraviolet Radiation Exposure Protocol
- Where
- 2 sites in Denmark, Greece
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Colonoscopy Training
Colonoscopy TRaining With or Without Artificial INtelligence Among Endoscopy Residents
Type of study: Randomized controlled study Investigated Procedure: Artificial Intelligence Software for Polyp Detection in Colonoscopy training Trial participants: Endoscopy trainees during their training with at least one year…
- Trial name
- c-TRAINER (NCT07420309)
- Testing
- Artificial Intelligence in colonoscopy, Conventional colonoscopy training
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Low Back Pain, Disability Physical
Psychological Predictors of Pain and Disability in Patients With Chronic Low Back Pain After Manual Therapy
Low back pain has been reported to cause more disability than any other musculoskeletal health condition worldwide. About eight out of ten people will experience back pain at least once in their lifetime.
- Conditions
- Low Back Pain, Disability Physical, Manual Theapy
- Trial name
- NCT07306312
- Testing
- Manual therapy, Manual therapy plus Pain Neuroscience Education
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Chronic Suppurative Lung Disease, Protracted Bacterial Bronchitis
Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases
This is a prospective, single-center, two-arm (1:1), assessor-blinded, randomized controlled clinical trial that will be conducted in collaboration with the outpatient clinic of the third Pediatric Pulmonology Unit, "Attikon"…
- Conditions
- Chronic Suppurative Lung Disease, Protracted Bacterial Bronchitis, Primary Ciliary Dyskinesia (PCD), Non Cystic Fibrosis Bronchiectasis
- Trial name
- NCT07376187
- Testing
- Videoconferencing (Vsee platform), Specially designed website (FysΑΩ)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- University of Thessaly
Healthy Volunteers, Health Promotion
Dance-Mindfulness Intervention for Well-Being in Recreational Adults
This 12-week study protocol outlines a randomized controlled trial designed to evaluate the effectiveness of a Dance-Mindfulness intervention integrating Modern Theatre Dance with mindfulness-based embodied practices to enhance…
- Trial name
- DanceMind (NCT07262177)
- Testing
- Dance-Mindfulness Intervention
- Where
- Greece
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Thessaly