Clinical trials: sponsored by University of Utah
Alzheimer Disease, Dementia
Ultrasonic Neuromodulation for Treatment of Cognitive Impairment
This study will evaluate a new form of non-invasive deep brain therapy for individuals with Alzheimer's disease. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation…
- Conditions
- Alzheimer Disease, Dementia, Cognitive Impairment
- Trial name
- NCT06135051
- Testing
- Diadem prototype
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Utah
PTSD
Ultrasonic Neuromodulation for Treatment of PTSD
This study will evaluate a new form of non-invasive deep brain therapy for individuals with post-traumatic stress disorder (PTSD).
- Trial name
- NCT06135064
- Testing
- Diadem
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Chronic Pain, Chronic Pain Syndrome
Deep Brain Therapy With Low-intensity Ultrasound for Generalized Chronic Pain
This study will evaluate a new form of non-invasive deep brain therapy for individuals with generalized chronic pain. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation…
- Conditions
- Chronic Pain, Chronic Pain Syndrome, Widespread Chronic Pain
- Trial name
- DBT (NCT05674903)
- Testing
- Verum stimulation with Diadem prototype
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Overweight, Obesity
Ultrasonic Treatment of Food Addiction
This study will evaluate a new form of non-invasive deep brain therapy for food addiction. Low-intensity transcranial focused ultrasound stimulation will first be delivered using a range of stimulation parameters during…
- Trial name
- USFADD (NCT06249711)
- Testing
- Active stimulation with Diadem ultrasonic transducer array
- Where
- United States
- Sponsor
- University of Utah
Neuropathic Pain, Chronic Pain
Noninvasive Modulation of Chronic Neuropathic Pain
This study will apply low-intensity transcranial focused ultrasound to dorsal root ganglia in patients with chronic neuropathic pain. The target will be validated using magnetic resonance imaging.
- Trial name
- NCT06249724
- Testing
- Active stimulation using low-frequency ultrasonic transducer
- Where
- United States
- Sponsor
- University of Utah
HPV Vaccination, Vaccine; Uptake
PREVENT HPV-Related Cancers - BootCamp Translation
This study will serve as one of the first to develop and test the effectiveness of strategies to promote HPV vaccination among diverse rural parents and caregivers of children ages 9-17 years in the Mountain West.
- Conditions
- HPV Vaccination, Vaccine; Uptake, Vaccination; Series Completion
- Trial name
- PREVENT (NCT06290206)
- Testing
- PREVENT - BCT
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Utah
Invasive Lobular Breast Carcinoma
[18F]Fluoroestradiol-PET/CT Imaging of Invasive Lobular Carcinoma
FES PET/CT imaging for invasive lobular cancer
- Trial name
- NCT04252859
- Testing
- [18F]Fluoroestradiol (FES) PET/CT
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Fatigue, Metastatic Prostate Carcinoma
Resistance Training +/- Creatine for Metastatic Prostate Cancer Patients
This trial studies how well resistance training with or without creatine monohydrate supplement works in improving body composition and health outcomes in patients with prostate cancer that has spread to other places in the body.
- Conditions
- Fatigue, Metastatic Prostate Carcinoma, Sedentary Lifestyle, Stage IV Prostate Cancer AJCC (American Joint Committee on Cancer) v8
- Trial name
- NCT03987217
- Testing
- Creatine Monohydrate, Exercise Intervention, Questionnaire Administration
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- University of Utah
Colorectal Cancer
Cetuximab in Third Line for Mutant APC, TP53 and RAS Patients With Refractory Metastatic Colorectal Cancer
A prospective, multi-center, phase II study of 21 patients to evaluate the efficacy of the epidermal growth factor receptor (EGFR) inhibitor, Cetuximab in patients with metastatic colorectal cancer (mCRC) harboring Adenomatous…
- Trial name
- APK Mutant (NCT04853043)
- Testing
- Cetuximab
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Utah
Prostate Cancer Metastatic to Bone
Radium-223 and Radiotherapy in Hormone-Naïve Men With Oligometastatic Prostate Cancer to Bone
This is a phase IIa, open label, single arm, and prospective study of hormone therapy-naïve men with oligometastatic prostate cancer to the bone.
- Trial name
- RROPE (NCT03304418)
- Testing
- Radium Ra 223 Dichloride, Radiation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Chronic Pain, Opioid Use Disorders
Mindfulness-Oriented Recovery Enhancement For Chronic Pain and Prescription Opioid Misuse in Primary Care
The central aim of this study is to test the efficacy of Mindfulness-Oriented Recovery Enhancement (MORE), an intervention designed to disrupt the risk chain leading from chronic pain to prescription opioid misuse and addiction.
- Trial name
- NCT02602535
- Testing
- Mindfulness-Oriented Recovery Enhancement, Support Group
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Utah
Chronic Pain Syndrome, Opioid Use
Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain
The primary aim of this pilot trial is to enhance the efficacy of the Mindfulness-Oriented Recovery Enhancement (MORE) intervention by adding neurofeedback (NF) of the Orbitofrontal Cortex (OFC) as an adjunct to the savoring…
- Trial name
- NCT04902339
- Testing
- Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- University of Utah
Intrauterine Devices, Copper, Metrorrhagia
Tracking IUD Bleeding Experiences: An Evaluation of Bleeding Profiles in New Intrauterine Device Users
This study aims to use validated tools as well as new technology to examine changes in bleeding patterns among women who are initiating the copper T380A IUD.
- Conditions
- Intrauterine Devices, Copper, Metrorrhagia, Menstruation, Menstrual Cycle
- Trial name
- TRIBE (NCT02311478)
- Testing
- T380A Intrauterine Copper Contraceptive
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Utah
Gastrointestinal Cancer, Depression
Ketamine-assisted Psychotherapy (KAP) for Patients With Existential Distress Associated With Non-operable GI Cancers
The goal of this open-label clinical trial is to assess the feasibility of Ketamine-assisted psychotherapy (KAP) studies for adults with non-operable GI cancers suffering with existential distress.
- Conditions
- Gastrointestinal Cancer, Depression, Anxiety
- Trial name
- TREK (NCT06001372)
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Contraception
Same Day Oral EC and Implant Initiation
This is a study for clients presenting for emergency contraception (EC). EC is used to prevent pregnancy after unprotected intercourse. Clients presenting for EC may be offered either the copper or hormonal IUD or oral EC.
- Trial name
- NCT04678817
- Testing
- Etonogestrel contraceptive implant with oral levonorgestrel, Levonorgestrel intrauterine device, Copper T380A intrauterine device
- Where
- 2 sites in United States
- Volunteers
- 306 people
- Sponsor
- University of Utah
Chronic Pain, Widespread
Treatment of Chronic Pain With Cannabidiol (CBD) and Delta-9-tetrahydrocannabinol (THC)
This is a study comparing the effects of Delta-9-Tetrahydrocannabinol (THC) versus Cannabidiol (CBD) versus a placebo on chronic non-cancer pain.
- Trial name
- NCT03215940
- Testing
- Delta-9-Tetrahydrocannabinol, Cannabidiol
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes
Diabetes Education and Care for Deaf Populations
This study will assess the feasibility and preliminary efficacy of a 10-week intervention called "Deaf Diabetes Can Together".
- Trial name
- NCT06577506
- Testing
- Deaf Diabetes Can Together
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Utah
Ocular Graft Versus Host Disease
Study for the Treatment of Ocular Chronic Graft-Versus-Host Disease (GVHD) With Amniotic Fluid Eye Drops (AFED)
A Randomized, Double-blinded, Placebo-Controlled Study for the Treatment of Ocular Chronic Graft Verses Host Disease with Processed Amniotic Fluid (pAF) Drops.
- Trial name
- NCT03298815
- Testing
- Amniotic Fluid Eye Drops (AFED), Saline Solution
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Epilepsy, Autobiographical Memory
Capturing Autobiographical Memory Formation in Real World Spaces Using Multimodal Recordings
The goal of this observational study is to develop novel methods for integrating multimodal data streams with invasive neural recordings to study autobiographical memory (AM) formation in individuals with implanted…
- Trial name
- CAPTURE (NCT06883981)
- Testing
- Free and Cued Recall Memory. Temporal Sequence and Spatial Memory
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female
Acupuncture Treatment of Chemotherapy-Induced Peripheral Neuropathy in Women
This pilot study aims to evaluate the feasibility to conduct a study of acupuncture treatment (AT) for Chemotherapy-Induced Peripheral Neuropathy (CIPN) at Huntsman Cancer Institute and to investigate changes in physiological…
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Breast Cancer Female, Gynecologic Cancer
- Trial name
- NCT04067544
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah