Clinical trials: sponsored by University of Utah
COVID-19
Health Information Technology for COVID-19 Testing in Schools (SCALE-UP Counts)
This project will address key testing challenges in Utah schools by building on collaborations with public school districts, private schools, charter schools and with Utah Department of Health on coronavirus disease (COVID-19)…
- Trial name
- NCT05112900
- Testing
- Text Messaging (TM), Text Messaging + Health Navigation (TM+HN)
- Where
- United States
- Volunteers
- 7,122 people, healthy volunteers welcome
- Sponsor
- University of Utah
Brain Tumor
[18F]Fluciclovine and [18F]FLT PET/CT Assessment of Primary High-Grade Brain Tumors
The hypothesis of this exploratory clinical trial in patients with high-grade a primary brain tumor who receive chemoradiation is that the PET imaging agents [18F]Fluciclovine and/or [18F]FLT will be a better predictor of tumor…
- Trial name
- NCT03276676
- Testing
- [18F]FLT, [18F]Fluciclovine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Infections
Vancomycin and Tobramycin Powder Use in Acute Open Fractures
The investigators overall aim of this study is to determine the difference in 6-month infection rates in patients treated with the combined vancomycin and tobramycin (VT) powder compared to the standard of care (SC).
- Trial name
- NCT05849090
- Testing
- Cephalosporin or clindamycin/vancomycin antibiotics.., Vancomycin and Tobramycin antibiotics.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Asthma
Timely Intravenous Magnesium for Asthma in Children
Many children currently being hospitalized with severe asthma could potentially avoid hospitalization and be sent home if their treatment in the emergency department was more effective.
- Trial name
- IMPACT-ED (NCT05166811)
- Testing
- Magnesium Sulfate, Heptahydrate, 0.9% saline
- Where
- 3 sites in United States
- Volunteers
- 52 people
- Sponsor
- University of Utah
Cerebral Palsy, Sialorrhea
Pharmacokinetics of Atropine Oral Gel
To evaluate the single-dose pharmacokinetics of atropine gel formulation after topical administration in the oral cavity of healthy adults.
- Trial name
- NCT05164367
- Testing
- Atropine sulfate gel (0.01%)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Sciatic Neuropathy, Radiculopathy
Effectiveness Study of Physical Therapy as an Adjunct to a Lumbar Therapeutic Selective Nerve Root Block
The purpose of this study is to determine if participation in physical therapy in conjunction with a selective nerve root block in the lumbar spine is more effective than just receiving the injection alone for patients with low…
- Conditions
- Sciatic Neuropathy, Radiculopathy, Intervertebral Disk Displacement
- Trial name
- NCT00934284
- Testing
- Lumbar injection, Rehabilitation following lumbar injection
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Children With Chronic Illnesses, Caregiver Burden
Siblings as Caregivers
The current body of research fails to acknowledge or understand what type of care children are giving to their siblings, yet it appears to be a common practice in many cultures.
- Trial name
- NCT05937724
- Testing
- Family Caregiving
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Utah
Contraception
Family Planning Elevated: Initiative Evaluation
Family Planning Elevated (FPE) is a statewide contraceptive initiative with two primary aims: 1) supporting existing and proposed legislative policy that expands family planning services in Utah among low-income individuals…
- Trial name
- NCT03877757
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Utah
Breast Cancer
Exercise Timing in Breast Cancer Patients
The purpose of this study is to demonstrate the feasibility of assigning breast cancer survivors currently receiving chemotherapy to exercise at a specific time of day, e.g., morning or afternoon/evening, for a 4-week exercise…
- Trial name
- NCT05821244
- Testing
- Exercise Timing Groups
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Utah
Suicide, Attempted, Suicidal Ideation
Brief Cognitive Behavioral Therapy Replication Trial
The overall goal for the proposed project is to test the effectiveness of BCBT for the prevention of suicide attempts in a sample of treatment-seeking U.S. military personnel and veterans.
- Trial name
- NCT03769259
- Testing
- Brief Cognitive Behavioral Therapy (BCBT), Present-Centered Therapy (PCT), Treatment as Usual (TAU)
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Obstructive Sleep Apnea
We-PAP: A Couples-based Intervention for Sleep Apnea
The purpose of this study is to develop, refine and evaluate the feasibility of a novel couples-based intervention to improve adherence for patients with obstructive sleep apnea (OSA).
- Trial name
- We-PAP (NCT04759157)
- Testing
- Couples-based treatment, Standardized education
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Utah
Mild Cognitive Impairment, Dementia
Implications for Management of PET Amyloid Classification Technology in the Imaging Dementia(IDEAS) Trial
The main purpose of this study is to build upon the evidence captured in the Imaging Dementia - Evidence for Amyloid Scanning (IDEAS; NCT02420756) trial to include valuable information regarding patient-reported outcomes and…
- Conditions
- Mild Cognitive Impairment, Dementia, Alzheimer's Disease
- Trial name
- IMPACT2 (NCT02781220)
- Where
- United States
- Volunteers
- 69 people
- Sponsor
- University of Utah
Postpartum Depression, Perinatal Depression
Maternal Mental Health Access - MaMa
This hybrid effectiveness-implementation project will allow the team to evaluate and refine implementation in preparation for future multisite trials to ultimately move the Evidence-Based Intervention (EBI) to scale among diverse…
- Trial name
- MaMa (NCT06049433)
- Testing
- Maternal Mental Health Access for Postpartum Depression- Prevention and UPLIFT- intervention, On-Demand + Discussion board (DB), Arm 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Migraine Disorders
Emotional Awareness and Expression Therapy (EAET) for Migraine
The goal of this feasibility study is to test the effect of a new behavioral intervention, Emotional Awareness and Expression Therapy (EAET), as a possible new treatment for people living with migraine.
- Trial name
- NCT05755698
- Testing
- Emotional Awareness and Expression Therapy
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Parkinson Disease, Orthostatic Hypotension
Effect of Levodopa on Cardiovascular Autonomic Function in Parkinson's Disease
Levodopa is a precursor of dopamine and is the treatment of choice to treat the motor symptoms of Parkinson's disease (PD); however, the effect of levodopa on cardiovascular autonomic function in PD is poorly understood.
- Trial name
- NCT05487300
- Testing
- Autonomic testing on and off levodopa
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone
Fluciclovine F18 PET/CT Imaging in Assessing Hormone-Naive Men With Prostate Cancer That Has Spread to the Bone
This trial studies how well fluciclovine 18F PET/CT imaging works in assessing hormone-naive men with prostate cancer that has spread to the bone. Fluciclovine 18F is a radioactive drug used to measure tumor growth.
- Conditions
- Metastatic Prostate Carcinoma, Prostate Carcinoma Metastatic in the Bone, Stage IV Prostate Cancer
- Trial name
- NCT03707184
- Testing
- Computed Tomography, Fluciclovine F18, Positron Emission Tomography
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Feasibility Studies
Feasibility Study of Resistance Training Intervention in Untrained Adolescents
Adolescents may have limited time to engage in physical activity during the school day prompting investigations of before and after-school times along with time efficient programming.
- Trial name
- NCT06710691
- Testing
- Physical activity intervention using traditional strength training protocols, Physical activity intervention using high-resistance circuit training.
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Utah
Major Depressive Disorder
A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder
We propose to determine if augmentation of electroconvulsive therapy (ECT) utilized for the treatment of major depressive disorder (MDD) with daily oral creatine will lead to an accelerated response to treatment, an overall…
- Trial name
- NCT04504253
- Testing
- Creatine monohydrate
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Metastatic Urothelial Carcinoma, Bladder Cancer
Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma
This is an open label, non-randomized phase 2 study of the combination of pembrolizumab and cabozantinib to assess overall response rate (ORR), progression free survival at 6 months (PFS6), and overall survival (OS) in patients…
- Trial name
- PemCab (NCT03534804)
- Testing
- Cabozantinib, Pembrolizumab
- Where
- 3 sites in United States
- Volunteers
- 37 people
- Sponsor
- University of Utah
Patient Satisfaction
Short Message Service Based Patient Education in Spine Patients
The investigators primary objective is to evaluate whether an SMS based patient education program improves patient satisfaction.
- Trial name
- SMS (NCT04458428)
- Testing
- SMS
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of Utah