Clinical trials: sponsored by University of Utah
Opioid Abuse, Prescription Drug Abuse (Not Dependent)
Validation of a Community Pharmacy-Based Prescription Drug Monitoring Program Risk Screening Tool
The goal of the study is to validate a Prescription Drug Monitoring Program-based opioid risk metric to discriminate between low, moderate, and high-risk opioid use disorder.
- Trial name
- PHARMSCREEN (NCT03936985)
- Where
- 2 sites in United States
- Volunteers
- 1,464 people, healthy volunteers welcome
- Sponsor
- University of Utah
Opioid Use
A Multimodal Analgesia Protocol Adapted for Ambulatory Surgery
The primary objective of this trial is to determine whether the combination of three non-opioid analgesics (multimodal analgesia) can significantly reduce or eliminate the need for opioids after ambulatory surgery.
- Trial name
- NCT04015908
- Testing
- Celecoxib, Acetaminophen, Pregabalin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Renal Cell Carcinoma
Cabometyx and Avelumab in Patients With Metastatic Renal Cell Carcinoma (mRCC)
This is an open-label, non-controlled, non-randomized, phase I dose-finding, of Cabometyx + Avelumab, to establish safety, feasibility, and the maximum tolerated dose (MTD) or Recommended Phase 2 Dose (RP2D) of Cabometyx in…
- Trial name
- NCT03200587
- Testing
- Avelumab, Cabozantinib
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Health Communication
Me & My Wishes: An Efficacy Trial Using Videos
The aim of this study is to determine whether the Me \& My Wishes intervention positively impacts communication of preferences among nursing home residents with dementia and their family caregivers and care team.
- Trial name
- NCT03861429
- Testing
- Me & My Wishes
- Where
- 8 sites in United States
- Volunteers
- 138 people
- Sponsor
- University of Utah
Elevated Blood Pressure, Habitual Sleep Duration of Less Than or Equal to 7 Hours
Sleep Technology Intervention to Target Cardiometabolic Health
The goal of this study is to test the efficacy of a behavioral sleep extension intervention on sleep duration, cardio-metabolic disease risk factors, and health behaviors among adults with elevated blood pressure/hypertension and…
- Trial name
- STITCH (NCT04766424)
- Testing
- Sleep extension intervention, Health education
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Major Depressive Disorder
Creatine for Treatment of Depression Associated With Type 2 Diabetes
The investigators hypothesize that the administration of a widely available, naturally occurring dietary supplement, creatine monohydrate, will reduce the severity of depression in individuals with type 2 diabetes.
- Trial name
- NCT03202095
- Testing
- Creatine Monohydrate
- Where
- United States
- Sponsor
- University of Utah
Infant,Premature, Bronchopulmonary Dysplasia
L-citrulline and Pulmonary Hypertension Associated With Bronchopulmonary Dysplasia
Bronchopulmonary dysplasia (BPD) is a chronic lung disease that affects up to 35% of very low birth weight infants (VLBW < 1500 g).
- Conditions
- Infant,Premature, Bronchopulmonary Dysplasia, Pulmonary Hypertension
- Trial name
- NCT03542812
- Testing
- L-Citrulline
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Utah
Wounds and Injuries
Processed Amniotic Fluid (pAF) for the Treatment of Chronic Wounds
A prospective randomized controlled study to determine the safety and feasibility of using processed amniotic fluid (pAF) to expedite healing in chronic wounds.
- Trial name
- NCT04438174
- Testing
- Processed Amniotic Fluid, Standard of Care Wound Treatment Regimen
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Utah
Perinatal Depression
Telehealth Group Intervention for Perinatal Depressive Symptoms
The goal of the project is to evaluate for the first time, the effectiveness of using a telehealth approach to reducing perinatal depressive symptoms in diverse groups of childbearing women; urban and rural-dwelling, and from…
- Trial name
- TePOP (NCT03932760)
- Testing
- UPLIFT Program, Attention Control Group
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Utah
Obesity
Increasing Treatment for Obesity Among Underserved Populations
The objective of this project is to evaluate strategies to increase patient engagement in evidence-based interventions (EBIs) for obesity.
- Trial name
- NCT05666323
- Testing
- Single Text Messaging (TM1), Patient Navigation (PN), Multiple Text Messaging (TM+)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Breast Cancer
A Comprehensive Oncology Rehabilitation and Exercise (CORE) Program Among Breast Cancer Survivors
The objective of this study is to demonstrate the feasibility and acceptability of the algorithm utilized within a cancer rehab program, named Comprehensive Oncology Rehabilitation and Exercise (CORE) program, among newly…
- Trial name
- CORE (NCT04594473)
- Testing
- Comprehensive Oncology Rehabilitation and Exercise (CORE) Program
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Utah
Atrial Fibrillation, Venous Thromboembolism
Warfarin Patient Self-management Implementation in the US Healthcare System
In the US, patients receiving warfarin therapy are rarely allowed to engage in patient self-management (PSM) which is less burdensome, less expensive, and safer than standard clinic-directed warfarin management.
- Conditions
- Atrial Fibrillation, Venous Thromboembolism, Heart Valve Diseases
- Trial name
- NCT04766216
- Testing
- Patient self-management, Usual care provided by anticoagulation providers
- Where
- 4 sites in United States
- Volunteers
- 150 people
- Sponsor
- University of Utah
Contraception
Assessing Adolescent Use of Nexplanon Over Time
The purpose of this study is to compare Nexplanon decision-making, uptake, satisfaction and contraceptive outcomes (continuation, switching, discontinuation) over a 12-month period among adolescents ages 15-18 to adolescents ages…
- Trial name
- NCT04889079
- Testing
- Contraceptive use (continuation/switching/discontinuation)
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pain, Chronic, Opioid Use
Comparing the Impact of Mindful Interoceptive Mapping and Mindful Breathing on Pain and Opioid Use
This is a single site, two-arm, parallel group randomized clinical trial comparing the effect of two mindfulness-based interventions (Mindful Interoceptive Mapping vs.
- Trial name
- NCT04523766
- Testing
- Mindfulness of Breath, Mindful Interoceptive Mapping
- Where
- United States
- Volunteers
- 149 people
- Sponsor
- University of Utah
Tics, Tic Disorders
Clinical Characteristics and Temporal Properties of Individual Tics in Persistent Tic Disorder
The goal of this clinical study is to learn more about the timing of tics (sudden, fast movements and sounds that people do and make without meaning to) in people who have multiple tics that have been going on for more than one…
- Conditions
- Tics, Tic Disorders, Vocal Tic, Motor Tic
- Trial name
- PTD (NCT06385535)
- Testing
- Habit Reversal Training (HRT)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Presbyopia
Smart Autofocusing Eyeglasses
A high-performance smart eyeglasses system with integrated sensing, actuation, control and data collection is being developed at the University of Utah.
- Trial name
- NCT03911596
- Testing
- Smart Autofocusing Eyeglasses
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- University of Utah
Photorefractive Keratectomy
Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK)
This is a randomized, double-masked, placebo-controlled study to determine the safety of pAF in patients who undergo PRK.
- Trial name
- NCT04281004
- Testing
- Amniotic Fluid (AFED), Saline Solution
- Where
- United States
- Volunteers
- 61 people
- Sponsor
- University of Utah
Malignant Neoplasm
Multi-Tracer Positron Emission Tomography in Patients With Solid Tumors
This clinical trial studies multi-tracer positron emission tomography in patients with solid tumors. Diagnostic procedures, such as multi-tracer positron emission tomography, may help measure a patient's response to treatment.
- Trial name
- NCT01243333
- Testing
- [F-18]fluorodeoxyglucose, [F-18]fluorothymidine, Positron Emission Tomography
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Utah
Chronic Pain
One MORE for Chronic Pain in Latinos
This study will be a single-site, two-arm randomized controlled trial conducted among Spanish-speaking chronic pain patients. Chronic pain patients will be randomized by a computer-generated randomization schedule with simple…
- Trial name
- NCT06316713
- Testing
- One MORE (Spanish Adaptation)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Utah
Cervical Radiculopathy, Cervical Spondylosis
Effectiveness of Cervical Transforaminal Epidural Steroid Injection
Study Purpose: This study is intended to monitor outcomes for 1 year following cervical TFESI. Based on current clinic volume and enrollment rates into a current study of cervical epidural injections that is nearing completion…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Disk, Herniated
- Trial name
- NCT04544683
- Testing
- Cervical Transforaminal Epidural Injection with dexamethasone sodium phosphate
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Utah