Clinical trials: sponsored by University of Utah
Cancer
SymptomCare@Home: Deconstructing an Effective Symptom Management Intervention
This project will determine the most important and cost effective components of SymptomCare@Home, a new approach to cancer chemotherapy symptom care that has been shown to reduce problematic symptoms through automated daily…
- Trial name
- SCH (NCT02779725)
- Testing
- SCC, Nurse Practitioner, DSS
- Where
- United States
- Volunteers
- 884 people
- Sponsor
- University of Utah
Chronic Pain
Mindfulness Based Chronic Pain Management: A Pilot Study
The primary objective for this pilot study is to determine if the Mindfulness-Based Chronic Pain Management (MBCPM) intervention would decrease pain and pain catastrophizing and increase pain acceptance in participants with…
- Trial name
- MBCPM (NCT01886885)
- Testing
- Mindfulness Based Chronic Pain Management Intervention
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Utah
Oncology
Remote COVID-19 Symptom Tracking for Cancer Patients at Home During the Pandemic
This project will evaluate the benefit of an automated home symptom monitoring system, Symptom Care at Home, to track COVID-19 symptoms, provide instructions to reduce COVID-19 exposure, and reduce cancer symptom severity during…
- Trial name
- NCT04464486
- Testing
- SCH Intervention
- Where
- United States
- Volunteers
- 301 people
- Sponsor
- University of Utah
Hip Fractures, Femur Fractures
Gonadal Radiation Exposure and Risk Secondary to Fluoroscopic Imaging During Trauma Surgery
The aim of this cohort study is to precisely measure patients' exposure to gonadal radiation during orthopaedic trauma surgery involving the acetabulum, pelvis, hip, and femur, and to apply these findings to a previously…
- Conditions
- Hip Fractures, Femur Fractures, Acetabular Fractures, Pelvic Injuries
- Trial name
- NCT02267330
- Testing
- Exposure Recording
- Volunteers
- 135 people
- Sponsor
- University of Utah
Substance Use, Mindfulness
Impact of Mindfulness Training on Adolescent Well-Being and Behavior
There is a broad consensus that preventing or delaying initiation of adolescent alcohol, tobacco, and other drug (ATOD) use can substantially improve both short- and long-term adolescent health.
- Conditions
- Substance Use, Mindfulness, Psychological Well-being
- Trial name
- NCT05537961
- Testing
- Mindfulness-Oriented Recovery Enhancement
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Procedural Anxiety, Procedural Pain
Remimazolam Sedation for Nerve Blocks
Observational study recording sedation and safety of patients undergoing remimazolam sedation for peripheral nerve blocks. Objectives: To explore the safety and efficacy of remimazolam for neuraxial procedures and peripheral…
- Trial name
- REMI-SEN (NCT05415202)
- Testing
- Remimazolam 20 MG [Byfavo]
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Utah
Atrial Arrhythmia
Prospective Evaluation Analysis and Kinetics Registry
In a cohort of patients electively treated for atrial arrhythmia with IV sotalol (initiation or dose escalation), this study will describe patient characteristics, short-term safety and efficacy, electrocardiographic monitoring…
- Trial name
- PEAKS (NCT05247320)
- Testing
- Sotalol Injection
- Where
- United States
- Volunteers
- 167 people
- Sponsor
- University of Utah
Healthy Controls, Alcohol Use Disorder
Deciphering the Role of Oxytocin in Motivation: an fMRI Study. Part II
The proposed study will investigate the effects of intranasal oxytocin administration on neural activity associated with social and non-social motivation.
- Trial name
- NCT02652195
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Utah
Diabetes Mellitus
Adapting and Assessing the Feasibility of a Diabetes Self-management Telehealth Intervention
The proposed project will use community based participatory research to adapt an existing diabetes self-management and education intervention with a telehealth intervention to be culturally relevant for rural English- and…
- Trial name
- NCT04600622
- Testing
- Rural Diabetes One-Day Education and Care program (R-D1D), Diabetes Education Materials
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of Utah
Sedentary Behavior, Aging
Development of the Isoped Device for Increasing Blood Flow in a Sedentary Aging Population
The Isoped (patented) is a portable medical device that provides a safe and engaging opportunity for regular physical activity to those with limited mobility and difficulties with performing traditional exercise tasks.
- Trial name
- NCT05044299
- Testing
- Isoped
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Pain
Multimodal Pain Management Following Primary TKA
The investigators plan to evaluate the length of time to discharge readiness between the groups (continuous femoral nerve blocks (cFNB) vs. liposomal bupivacaine (LB) vs.
- Trial name
- NCT02369523
- Testing
- Exparel, Ropivacaine cocktail (PIC), Bupivacaine
- Where
- United States
- Volunteers
- 84 people
- Sponsor
- University of Utah
Down Syndrome, Cardiovascular Risk Factor
Vascular Health and Risk Factors in Children With Down Syndrome
This is a prospective, multicenter, cross-sectional study to evaluate prevalence of vascular risk factors in children with Down Syndrome and to determine the association between vascular disease risk factors and objective markers…
- Conditions
- Down Syndrome, Cardiovascular Risk Factor, Atherosclerosis
- Trial name
- NCT04735874
- Testing
- Evaluate vascular disease risk factors in children with Down Syndrome, Determine the associations between cardiovascular disease risk factors and markers of early atherosclerosis in children with Down Syndrome
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Utah
Opioid Misuse, Musculoskeletal Pain
Physical Therapists Identifying Patients With Opioid Misuse
The purpose of this study is to develop and operationalize key procedures for physical therapists (n = 12) to address patients who are at risk for or have opioid misuse (OM).
- Trial name
- NCT05497154
- Testing
- Training Arm
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Utah
Non-specific Low Back Pain
The Effect of Combining Spinal Manipulation and Dry Needling in Individuals With Low Back Pain
The goal of this study is to enroll and randomize 99 participants with non-specific low back pain into a multimodal strategy of treatment consisting of a combination of dry needling (DN) and spinal manipulation therapy (SMT), DN…
- Trial name
- SMTDNLBP (NCT05802901)
- Testing
- Spinal manipulation, Dry needling, Spinal manipulation and dry needling
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- University of Utah
Anesthesia
Efficacy and Safety of a Single Syringe Total Intravenous Anesthesia With Propofol and Remifentanil: A Prospective Cohort Study
The purpose of this prospective observational study was to evaluate the efficacy and safety of single syringe TIVA with propofol and remifentanil.
- Trial name
- NCT04987580
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Utah
Fibromyalgia, Obesity
Nutrition and Coping Education for Symptom and Weight Management for Fibromyalgia
Research has shown that weight problems are very common in fibromyalgia. Research also suggests that overweight and obesity may contribute to worsening of fibromyalgia symptoms and biochemical vulnerability associated with…
- Trial name
- NCT00925431
- Testing
- Lifestyle Modification, Supportive education
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Utah
Opioid-use Disorder
Digital Therapeutic Development of Virtual Cognitive-Affective Training for Opioid Use Disorder
This is a Phase 1 trial that aims to establish the safety of MORE-VR, as well as to collect feasibility, usability, and engagement data, for patients receiving medications for opioid use disorder (mOUD).
- Trial name
- NCT05034276
- Testing
- MORE-VR
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Utah
Surgery, Myopia
Topo-guided LASIK and Photorefractive Keratectomy vs Wavefront LASIK and Photorefractive Keratectomy
This study evaluates the difference in results between eyes that have been treated wavefront optimized laser vision correction (either LASIK or Photorefractive Keratectomy) compared to eyes treated with topography-guided laser…
- Trial name
- NCT03075176
- Testing
- Wavefront optimized LASIK, Wavefront optimized Photorefractive Keratectomy, Topography-guided LASIK
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Utah
Chronic Pain
Treating Opioid Misuse Via Mindfulness-Based Just-in-Time Adaptive Intervention
This pilot RCT will examine the preliminary efficacy of a telehealth version of Mindfulness-Oriented Recovery Enhancement (MORE) enriched with a smartphone-based just-in-time adaptive intervention (JITAI) for patients with…
- Trial name
- MORE-JITAI (NCT04567043)
- Testing
- MORE+JITAI, Supporive Psychotherapy
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- University of Utah
Opioid-use Disorder
Ketamine Assisted Psychotherapy for Opioid Use Disorder
This pilot clinical trial aims to assess the preliminary efficacy of ketamine as an adjunct for a mindfulness-based intervention for opioid use disorder.
- Trial name
- NCT04892251
- Testing
- MORE+KAP, MORE
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah