Clinical trials: sponsored by University of Utah
Subdermal Skin Tightening
Renuvion/J-Plasma for Subdermal Skin Tightening and Contouring of the Upper Arms: Dissection Technique Comparison
The Renuvion/J-plasma cold atmospheric plasma device has been in clinical use in aesthetics since its approval by the FDA in 2012, but no rigorous clinical trials have been published to quantify the effect of the skin tightening…
- Trial name
- NCT04902599
- Testing
- Renuvion/j-Plasma procedure using blunt dissection technique, Renuvion/j-Plasma procedure using ultrasound-guided dissection technique
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Utah
Vascular Diseases
Autophagy Maintains Vascular Function Through a Novel Glycolysis-linked Pathway Regulating eNOS
Aging is inevitable and is the primary risk factor for developing cardiovascular disease. The molecular mechanisms that drive vascular dysfunction in the context of aging are incompletely understood.
- Trial name
- NCT04200560
- Testing
- Rhythmic Handgrip Exercise, Chronic Exercise Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Utah
Noninvasive Ventilation, Speech Intelligibility
Facilitating Patient Communication During Noninvasive Ventilation
Assessing speech intelligibility in a pilot study of patients speaking with a mask microphone while being treated with standard of care non-invasive ventilation.
- Trial name
- NCT04912544
- Testing
- Noninvasive Ventilation Mask Microphone
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Utah
Osteoarthritis
Resiliency in Total Joint Arthroplasty
The investigators primary objective is to determine how does participation in StreaMD affect patient reported outcomes after Total Hip Arthroplasty (THA) or Total Knee Arthroplasty (TKA)?
- Trial name
- NCT04357262
- Testing
- StreaMD
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Heterotopic Ossification
Influence of Naproxen on Heterotropic Bone Formation Following Hip Arthroscopy
In a brief summary the study would like to evaluate the effectiveness of Naproxen in preventing radiographically detected heterotopic ossification following hip arthroscopy for the treatment of femoroacetabular impingement.
- Trial name
- NCT01539447
- Testing
- Naproxen
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Utah
Amputations, Peripheral Nerve Injury
Micro-Electrodes Implanted in a Human Nerve
The main objective of the intervention in the study is devise feasibility using high-count microelectrode arrays implanted into peripheral nerves of patients with limb amputations or peripheral nerve injury.
- Conditions
- Amputations, Peripheral Nerve Injury, Spinal Cord Injury
- Trial name
- NCT02034461
- Testing
- Utah Slanted Electrode Array
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Contraception
RAPID EC - Rct Assessing Pregnancy With Intrauterine Devices for EC
This study is a randomized trial of two IUDs for emergency contraception: the copper IUD, the most effective method of emergency contraception vs.
- Trial name
- NCT02175030
- Testing
- Copper IUD, Levonorgestrel IUD
- Where
- 6 sites in United States
- Volunteers
- 711 people
- Sponsor
- University of Utah
Physical Inactivity
Translational Control of Anabolic Resistance in Aging Muscle
This is an interventional study enrolling older individuals aged 60-85y to observe changes during physical inactivity. This study is investigating the relation between short-term physical inactivity and the impact of muscle…
- Trial name
- NCT03839628
- Testing
- Reduced Physical Activity
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Utah
Insulin Resistance
Ceramides in Muscle During Insulin Resistance
Overnutrition and physical inactivity promote the accumulation of sphingolipids such as ceramides which block insulin signaling and anabolic metabolism.
- Trial name
- NCT03731598
- Testing
- bed rest
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Utah
Healthy
Blood and Muscle Response to Cheddar Cheese in Healthy Adults
The goal of this project is to use a cross over design in young healthy male and female adults: 1. To determine the amino acid blood response to the acute ingestion of cheddar cheese in comparison to that of milk. 2.
- Trial name
- NCT04660877
- Testing
- Cheddar Cheese, Milk
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Utah
Reduced Physical Activity
Mechanisms of Skeletal Muscle Insulin Resistance in Older Adults
The over-65 population is not only increasing at an alarming rate, but because six out of 10 will be managing more than one chronic condition by 2030, they will make up a much greater proportion of hospitalizations than ever…
- Trial name
- NCT02971098
- Testing
- Reduced activity
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Utah
Muscle Atrophy, Physical Deconditioning
Reducing Falls With RENEW in Older Adults Who Have Fallen
This clinical trial will compare the effects of a high intensity Resistance Exercise via Negative Work (RENEW) vs. Traditional resistance exercise (TRAD) as part of a mult-component exercise and fall-reduction program on muscle…
- Trial name
- NCT01080196
- Testing
- RENEW
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- University of Utah
Craniocerebral Trauma, Intracranial Aneurysm
Hypovitaminosis D in Neurocritical Patients
Vitamin D has been shown to impact prognosis in a variety of retrospective and randomized clinical trials within an intensive care unit (ICU) environment.
- Conditions
- Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries
- Trial name
- NCT02881957
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- University of Utah
Melanoma
Neoadjuvant Trial of Nivolumab in Combination With HF10 Oncolytic Viral Therapy in Resectable Stage IIIB, IIIC, IVM1a Melanoma
This is a single-arm, open label, Phase II study evaluating the safety and efficacy of neoadjuvant Nivolumab and HF10 in resectable stage IIIB, IIIC, and IVM1a melanoma.
- Trial name
- NCT03259425
- Testing
- Nivolumab, HF10
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Utah
Stroke
Piloting GETCare: A Remote Goal-based Education and Skills Training Program for Caregivers Poststroke
The purpose of this study was to evaluate the GETCare program, a Goal-based Education and skills Training program for Caregivers poststroke.
- Trial name
- GETCare (NCT05403021)
- Testing
- GETCare Intervention
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pain
Methadone Pharmacokinetics and Cardiac Effects in Newborns
The Primary objectives of this proposal are to determine the population kinetics for methadone and its enantiomers in preterm newborns and infants at 29 weeks to 48 weeks post menstrual age (PMA) who are 1 week old and older and…
- Trial name
- NCT00715988
- Testing
- Methadone HCl Inject 10 mg/ml (will require dilution), Methadone
- Where
- 2 sites in United States
- Volunteers
- 7 people
- Sponsor
- University of Utah
Fabry Disease
Pre-Clinical White Matter Changes and Associated Connectivity Effects in Fabry Disease
The purpose of this research project is: to use an advanced quantitative MRI technique (FBFI) to detect and quantify brain lesion in patients with FD to use fMRI to identify altered brain function to use FBFI and fMRI together to…
- Trial name
- NCT03678324
- Testing
- Functional MRI and fast bound-pool fraction imaging
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Neurofibromatosis Type 1 (NF1)
Vitamin D Supplementation for Adults With Neurofibromatosis Type 1 (NF1)
This clinical trial is conducted by one of 4 locations; University of British Columbia (Vancouver, CA), University of Utah (Salt Lake City, UT, USA), University of Cincinnati (Cincinnati, OH, USA), and University of Hamburg…
- Trial name
- VitDBoneNF1 (NCT01968590)
- Testing
- Cholecalciferol
- Where
- 3 sites in United States, Canada
- Volunteers
- 26 people
- Sponsor
- University of Utah
Anemia, ASXL1 Gene Mutation
Allogeneic Stem Cell Transplantation for Multiple Myeloma and Myelofibrosis
This phase II trial studies how well busulfan, fludarabine, donor stem cell transplant, and cyclophosphamide in treating participants with multiple myeloma or myelofibrosis.
- Conditions
- Anemia, ASXL1 Gene Mutation, EZH2 Gene Mutation, IDH1 Gene Mutation
- Trial name
- NCT03303950
- Testing
- Busulfan, Cyclophosphamide, Fludarabine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Utah
Cancer
FDG-Positron Emission Tomography (PET)/CT In the Evaluation of Persistent Febrile Neutropenia in Cancer Patients
Patients must be currently treated at the Huntsman Cancer Institute or Intermountain Primary Children's Medical Center to be eligible for this study.
- Trial name
- NCT00707213
- Testing
- [18F]fluoro-2-deoxy-D-glucose (FDG)
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of Utah