Clinical trials: sponsored by University of Utah
Brain Tumors, Cancer
Multi-Tracer PET Assessment of Primary Brain Tumors
The standard treatment approach for patients with high-grade primary brain tumors includes maximum feasible surgical resection, followed by 6 weeks of concurrent cranial irradiation and daily low-dose temozolomide chemotherapy…
- Trial name
- NCT00813566
- Testing
- [18F]fluoro-2-deoxy-D-glucose (FDG), 3'-deoxy-3'-[18F]fluorothymidine (FLT), [15O]-H2O
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Iron Overload
The Iron Content of Ferritin in Serum and Urine of Children With High Serum Ferritin Levels
A serum ferritin level can reflect the total body iron content, thus a very low serum ferritin is commonly used as an indicator of iron deficiency and a very high serum ferritin is commonly used as a marker of iron overload.
- Trial name
- NCT03777904
- Testing
- Serum Ferritin level, Serum Ferritin iron content, Urine Ferritin level
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Overactive Bladder, Voiding Disorders
Feasibility of Parasacral Transcutaneous Electrical Nerve Stimulation PTENS for Voiding Dysfunction in Peds Population
Pilot study for determining feasibility of home parasacral transcutaneous electrical nerve stimulation in treatment of urinary urgency and incontinence.
- Conditions
- Overactive Bladder, Voiding Disorders, Incontinence, Urinary
- Trial name
- NCT04570605
- Testing
- parasacral transcutaneous electrical nerve stimulation (PTENS), Standard Urotherapy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Aspirin Sensitivity
Asprin Dosing Estimator in Healthy Adults
Understanding sources of variability in human drug dosing is important to the beneficial and safe use of any drug. Understanding and applying the science of individualizing a drug dose to a patient is called precision medicine.
- Trial name
- NCT04040465
- Testing
- Aspirin
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pregnancy, Fertility
Creighton Model Effectiveness, Intentions and Behaviors Assessment (CEIBA)
The Creighton Model (CrM) FertilityCare System is a natural family planning method that teaches couples to recognize and chart the signs of fertility and infertility in the woman's cycle and to use that knowledge to either…
- Trial name
- CEIBA (NCT01012596)
- Testing
- Creighton Model System of Natural Family Planning
- Where
- 18 sites in United States, Canada
- Volunteers
- 624 people, healthy volunteers welcome
- Sponsor
- University of Utah
Melanoma (Skin)
Aspirin as an Ultraviolet (UV) Protectant in Human Subjects at Risk for Melanoma
This is a phase II placebo-controlled intervention trial assessing aspirin (ASA) as a UV protectant in patients at risk for melanoma.
- Trial name
- NCT04066725
- Testing
- Aspirin 81 mg, Aspirin 325mg
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Utah
Melanoma (Skin)
Metabolomic and Inflammatory Effects of Oral Aspirin (ASA) in Subjects at Risk for Melanoma
This is an open label phase II pilot study assessing the metabolomic and inflammatory effects of oral aspirin (ASA) in human subjects at risk for melanoma.
- Trial name
- NCT04062032
- Testing
- Aspirin 81 mg, Aspirin 325mg
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Utah
Thromboembolism, Postpartum DVT
Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery
The aim of this study is to evaluate the efficacy of two dosing regimens of low molecular weight heparin (LMWH) to reach prophylactic anti-factor Xa levels in post-cesarean delivery women.
- Conditions
- Thromboembolism, Postpartum DVT, Thrombosis
- Trial name
- NCT04305756
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Utah
Pain, Osteoarthritis, Knee
Brief Nurse-led Mindfulness Based Intervention
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The feasibility, acceptability, and clinical effects of the nurse-led, very brief, preoperative mindfulness based intervention for hip and knee…
- Conditions
- Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04800354
- Testing
- Nurse-led Mindfulness Based Intervention, Nurse-led Pain Psychoeducation
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- University of Utah
Chronic Pain
Behavioral Interventions for Chronic Pain and Opioid-Related Problems
The purpose of this study is to examine the effects of Mindfulness-Oriented Recovery Enhancement versus a social support group (supportive counseling) intervention for chronic pain patients receiving long-term opioid…
- Trial name
- NCT03298269
- Testing
- Mindfulness-Oriented Recovery Enhancement, Supportive Counseling
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of Utah
Grief
Group Therapy For Dementia Caregivers At Risk For Complicated Grief
The investigators are adapting Complicated Grief Group Therapy (CGGT) for soon-to-be bereaved dementia caregivers at risk for complicated grief-Pre-Loss Group Therapy (PLGT) to facilitate healthy death preparedness and eventual…
- Trial name
- PLGT (NCT03177772)
- Testing
- Pre-loss group therapy
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
Neurogenic Bladder, Spinal Cord Injuries
Patient Reported Outcomes for Bladder Management Strategies in Spinal Cord Injury
The investigators goal is to create a better understanding of patient reported outcomes for bladder management strategies (clean intermittent catheterization (CIC), indwelling catheter (IDC) and bladder surgery.
- Conditions
- Neurogenic Bladder, Spinal Cord Injuries, Quality of Life, Incontinence
- Trial name
- NBRG-PCORI (NCT02616081)
- Testing
- Clean Intermittent Catheterization, Indwelling Catheter, Surgery
- Where
- 3 sites in United States
- Volunteers
- 1,479 people, healthy volunteers welcome
- Sponsor
- University of Utah
Low Back Pain
Telehealth Physical Therapy for Chronic Back Pain - Ancillary Study to NCT03859713
This study evaluated the feasibility of an 8-week physical therapy program for persons with chronic low back pain provided entirely using telehealth with real-time, interactive video sessions with a physical therapist.
- Trial name
- TeleOPT (NCT05103462)
- Testing
- Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 126 people
- Sponsor
- University of Utah
Pelvic Fracture, Urethra Tear
Primary Urethral Realignment Versus Suprapubic Cystostomy After Pelvic Fracture Urethral Injury
Pelvic fracture urethral injuries (PFUI) occur in up to 10% of pelvic fractures. It remains controversial whether initial urethral realignment after PFUI decreases rates of urethral obstruction and the need for subsequent…
- Conditions
- Pelvic Fracture, Urethra Tear, Urethra Injury Male, Trauma
- Trial name
- NCT03195179
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Utah
Pancreatic Cancer
Multi-Tracer PET Prediction and Assessment of Response to Gemcitabine in Pancreatic Cancer Patients
Study of multi-tracer PET scans to assess response to gemcitabine in pancreatic cancer
- Trial name
- NCT02245217
- Testing
- PET/CT scan to assess treatment efficacy
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of Utah
Cancer, Brain Tumors
[F-18] Fluorothymidine (FLT) Imaging on Patients With Primary Brain Tumors
Despite significant advances in the understanding of brain tumor biology and genetics as well as improvements in surgical techniques, radiotherapy administration, and chemotherapy methods, many primary brain tumors remain…
- Trial name
- NCT00707343
- Testing
- FLT-PET Imaging
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Venous Thromboembolism, Bleeding as Surgical Complication (Treatment)
Enoxaparin Versus Placebo for Venous Thromboembolism Prevention in Low Risk Cancer Patients After Surgical Procedures: a Randomized, Double Blind, Placebo Controlled Clinical Trial Pilot Study
Post-surgical bleeding is a major source of morbidity in cancer patients, and ramifications can include need for transfusion, increased length of hospital stay, unexpected return to the operating room, or even death.
- Conditions
- Venous Thromboembolism, Bleeding as Surgical Complication (Treatment), Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- NCT03988231
- Testing
- Receipt of enoxaparin
- Sponsor
- University of Utah
Multiple Sclerosis, Vertigo
Gaze and Postural Stability in Multiple Sclerosis
In order to provide information that will improve therapy, the goals of this project are to determine if persons with MS with complaints of dizziness and at risk for falls can improve their balance and vision stability as a…
- Conditions
- Multiple Sclerosis, Vertigo, Dizziness, Falls Injury
- Trial name
- GPS (NCT03521557)
- Testing
- Gaze and Postural Stability, Standard Care Control
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Utah
Colorectal Cancer, Appendiceal Cancer
Intraperitoneal Oxaliplatin in Combo w IV mFOLFIRI for Peritoneal Carcinomatosis From Colorectal & Appendiceal Cancer
This study is a prospective, multi-center, open-label phase I trial designed to determine the maximun tolerated dose of IP oxaliplatin when given in combination with mFOLFIRI.
- Conditions
- Colorectal Cancer, Appendiceal Cancer, Peritoneal Carcinoma
- Trial name
- IPOX-FOLFIRI (NCT04158349)
- Testing
- Oxaliplatin, mFOLFIRI
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Utah
Prostate Adenocarcinoma
Perioperative Atezolizumab With MVA-BN-Brachyury and PROSTVAC For Intermediate-Risk And High-Risk Localized Prostate Cancer
This study is a prospective, open label, single arm phase II trial. A total of 22 patients will be treated with atezolizumab, PROSTVAC, and pre-operative MVA-BN-Brachyury to confirm the efficacy of prostatic combination…
- Trial name
- AtezoVax (NCT04020094)
- Testing
- MVA-BN-Brachyury
- Where
- United States
- Sponsor
- University of Utah