Clinical trials: sponsored by University of Utah
Asthma
Redesigning Ambulatory Care Delivery to Enhance Asthma Control in Children
The investigators have developed a tool to facilitate asthma self-management in children, the electronic-AsthmaTracker (e-AT). The e-AT changes ambulatory asthma care delivery to a new model that is continuous and proactive…
- Trial name
- NCT02409277
- Testing
- Experimental: Standard vs Intensive e-AT Intervention
- Where
- United States
- Volunteers
- 926 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hydrocephalus
Ventricular Size Involvement in Neuropsychological Outcomes in Pediatric Hydrocephalus
This multicenter, prospective study of children with hydrocephalus will examine whether or not ventricle size is associated with poor cognitive outcomes.
- Trial name
- VINOH (NCT01797627)
- Where
- 8 sites in United States, Canada
- Volunteers
- 78 people
- Sponsor
- University of Utah
Malnutrition
Pilot Study of the Safety and Efficacy of Oxandrolone in the Prevention and Treatment of Malnutrition in Infants
Oxandrolone is an anabolic steroid, marketed in the United States as an adjunctive therapy to combat weight loss resulting from chronic infection, extensive surgery, severe trauma, protein catabolism associated with prolonged…
- Trial name
- NCT01048632
- Testing
- Oxandrolone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Major Depressive Disorder
Endogenous Opioid Modulation by Ketamine
Demonstrate the acute effects of ketamine on endogenous µ-opioid neurotransmission in humans.
- Trial name
- NCT03051945
- Testing
- Ketamine Hydrochloride, Normal saline
- Where
- United States
- Sponsor
- University of Utah
Epilepsy
Cannabidiol (CBD) to 27 Patients (Aged 2 Years - 19 Years) With Drug Resistant Epilepsy
Part A: To evaluate the safety and tolerability of multiple ascending doses of GWP42003-P compared with placebo with respect to: Incidence, type and severity of adverse events (AEs) Effect on vital signs, including weight Effect…
- Trial name
- NCT02286986
- Testing
- Cannabidiol
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- University of Utah
Treatment Resistant Depression
Neural and Antidepressant Effects of Propofol (Phase 2)
Moderate-intensity propofol treatments will be administered to participants who are non-responders at the end of Phase 1.
- Trial name
- NCT03923361
- Testing
- Diprivan
- Where
- United States
- Sponsor
- University of Utah
Hepatocellular Carcinoma
Nivolumab and Bevacizumab in Patients With Advanced and or Metastatic Hepatocellular Carcinoma
This is an open label, phase I study to test for maximum tolerated dose (MTD) or recommended phase II dose (RP2D) of the combination of nivolumab and bevacizumab.
- Trial name
- NUANCE (NCT03382886)
- Testing
- Nivolumab, Bevacizumab
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Utah
Hip Dysplasia
Stress Analysis of Hip Dysplasia
The main objective of this study is to predict cartilage contact pressures in the hip after periacetabular osteotomy (PAO).
- Trial name
- NCT01575977
- Volunteers
- 12 people
- Sponsor
- University of Utah
Hip Dysplasia
Discovering the Gene(s) Causing Developmental Dysplasia of the Hip (DDH)
The primary objective of the study is to find the gene(s) responsible for causing DDH. The secondary objective of the study is to determine the mode of genetic transmission of DDH.
- Trial name
- NCT01193673
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Utah
Polycythemia Vera, Essential Thrombocythemia
Polycythemia Vera, Myelofibrosis and Essential Thrombocythemia: Identification of PV, MF & ET Genes
The purpose of this project is to find genes whose mutations cause Polycythemia Vera, Essential Thrombocythemia and Primary Myelofibrosis.
- Conditions
- Polycythemia Vera, Essential Thrombocythemia, Myelofibrosis
- Trial name
- NCT00715247
- Where
- United States
- Volunteers
- 726 people, healthy volunteers welcome
- Sponsor
- University of Utah
Opioid Misuse
Community Pharmacists and Opioid Misuse
Opioid medication misuse and overdose have reached epidemic proportions in the US. Community pharmacy is a potentially valuable resource for addressing opioid medication misuse.
- Trial name
- NCT03149718
- Testing
- Brief Intervention Medication Therapy Management, Standard Medication Counseling (SMC)
- Where
- 2 sites in United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Utah
Neonatal Screening
The Effect of Electronic Informed Consent Information (EICI) on Residual Newborn Specimen Research
Obtaining adequate informed consent from potential research participants is a significant challenge for biobank-dependent research.
- Trial name
- EICI (NCT03141307)
- Testing
- EICI Movie, EICI App, Control
- Where
- United States
- Volunteers
- 711 people, healthy volunteers welcome
- Sponsor
- University of Utah
Nail Psoriasis
308nm Excimer Laser for Treatment of Fingernail Psoriasis
Psoriasis is a common skin disease, which affects 2-3% of the population. Up to two third of patients with psoriasis develop nail changes. These visible changes can be painful and disabling and are associated with social stigma.
- Trial name
- NAPSI (NCT02168933)
- Testing
- 308 nm excimer laser
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Propionibacterium Acnes
Propionibacterium Acnes in Shoulder Arthroplasty
The investigator's plan to determine whether pre-operative skin preparation with hydrogen peroxide alters rates of P acnes culture positivity.
- Trial name
- NCT03057821
- Testing
- 3% hydrogen peroxide
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Utah
Carpal Tunnel Syndrome
Ultrasonographic Assessment of Carpal Tunnel Syndrome
Mucopolysaccharidosis are lysosomal storage disorders such as Hunter, Hurler, and Sanfilippo syndromes. These patients have a genetic enzyme deficiency that results in the inability to degrade glycosaminoglycans.
- Trial name
- NCT02196220
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Utah
Osteoarthrosis of the Carpometacarpal Joint of the Thumb
Postoperative Rehabilitation Following Trapeziectomy and Ligament Reconstruction Tendon Interposition
Carpometacarpal (CMC) arthritis of the thumb joint ('basal arthritis') is a common entity treated by hand surgeons in our society.
- Trial name
- LRTI (NCT01425034)
- Testing
- casts for the thumb, Motion group
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- University of Utah
Trigger Finger
Surgical Treatment of Adult Trigger Finger
Trigger finger is a condition commonly treated with surgical intervention, yet no specific incision type has been associated with improved or worsened scar quality or outcome.
- Trial name
- NCT02196233
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Utah
Atrial Fibrillation
Efficacy of Optison Echo Contrast to Detect Thrombus in Left Atrial Appendage
The investigators intend to determine if using Optison echocardiography contrast increases sensitivity and specificity of detecting left atrial appendage thrombus in transesophageal echocardiography studies as opposed to standard…
- Trial name
- DOLOP (NCT01721447)
- Testing
- Optison echocardiography contrast agent
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Congenital Hand Deformities
Syndactyly Repair: Comparison of Skin Graft and No Skin Graft Techniques
Syndactyly is a relatively common congenital abnormality of the hand occurring approximately 1 out of 2500 live births (1). It can be simple, meaning only skin and soft tissues are shared, or complex, meaning the bone or nail…
- Trial name
- NCT01416090
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Utah
Recurrent Glioma
Repeat Radiation, Minocycline and Bevacizumab in Patients With Recurrent Glioma
The primary objective of step 1 is the rate of adverse events of minocycline and bevacizumab during reirradiation and of step 2 is the response rate to bevacizumab, reirradiation, and minocycline.
- Trial name
- RAMBO (NCT01580969)
- Testing
- Bevacizumab, Minocycline, Radiation
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of Utah