Clinical trials: sponsored by University of Utah
Chronic Kidney Disease
Pilot Study of Sodium Bicarbonate in Generally Healthy People With Low Bicarbonate
The goal of this pilot study is to determine whether oral sodium bicarbonate can raise low serum bicarbonate concentration in people without chronic kidney disease (CKD).
- Trial name
- NCT02743650
- Testing
- Sodium bicarbonate
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Utah
Advanced GI Cancer
Phase I Study MK-3475 With Chemotherapy in Patients With Advanced GI Cancers
This is a Phase I dose escalation trial to assess MTD of MK-3475 in combination with mFOLFOX6 followed by a safety expansion open label, nonrandomized trial with MK-3475 at MTD in combination with mFOLFOX6 and supplemental…
- Trial name
- MK-3475 GI (NCT02268825)
- Testing
- MK-3475
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Utah
Gulf War Illness
Probiotic (VSL #3) for Gulf War Illness
The overall objective is to determine whether VSL #3 will improve 1) intestinal symptoms of Irritable Bowel Syndrome (IBS) and 2) non-intestinal symptoms (fatigue, joint pain, insomnia, general stiffness and headache) associated…
- Trial name
- NCT02011542
- Testing
- VSL#3
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Utah
Chorioamnionitis, Intrapartum Fever
Intrapartum Fever: Antibiotics Versus no Treatment
The purpose of this study is to determine whether antibiotics can be safely avoided in women who develop a fever during labor. Because investigators have no accurate tests to determine whether women who develop fever during labor…
- Conditions
- Chorioamnionitis, Intrapartum Fever, Intra-amniotic Infection
- Trial name
- NCT03168178
- Testing
- Standard Antibiotic Treatment, No Antibiotic Treatment
- Where
- United States
- Sponsor
- University of Utah
Venous Thromboembolism, Deep Venous Thrombosis
Twice Daily Enoxaparin Prophylaxis in Reconstructive Surgery Patients
Blood clots that form in the extremities (deep venous thrombosis) and lungs (pulmonary embolus) are feared complications of reconstructive surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus
- Trial name
- NCT02687204
- Testing
- Twice daily enoxaparin prophylaxis, Real time dose adjustment
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Utah
Obesity, Physical Activity
Coalition for a Healthier Community-Utah Women and Girls - Phase II (UWAG-II)
This 12-month randomized trial is designed to evaluate the impact of low intensity (quarterly) versus high intensity (monthly) wellness coaching programs on women's success achieving individual health goals related to active…
- Conditions
- Obesity, Physical Activity, Diabetes
- Trial name
- UWAG-II (NCT02470156)
- Testing
- High Intensity Arm (Intervention), Low Intensity Arm (Comparison)
- Where
- United States
- Volunteers
- 556 people, healthy volunteers welcome
- Sponsor
- University of Utah
Low Back Pain
Comparative Effectiveness of Acute Low Back Pain Management
Current practice guidelines for patients with acute low back pain (LBP) recommend a stepped care approach with initial treatment of education and advice to remain active.
- Trial name
- NCT01726803
- Testing
- Early Physical Therapy with Usual Care, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of Utah
Mindfulness
Dissecting De-automatization
The proposed study will assess the effects of mindfulness meditation training on an eye blink conditioning (EBC) task in a sample of novice meditators.
- Trial name
- NCT03456505
- Testing
- Mindfulness Meditation Training, Active Listening
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Utah
Fibromyalgia Pain
Propranolol for Treating Fibromyalgia Pain
The purpose of the study to evaluate the feasibility of using low dose propranolol for people with fibromyalgia.
- Trial name
- NCT03029845
- Testing
- Propranolol 1, Propranolol 2
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Congenital Trigger Thumb, Tenosynovitis
The Natural History of Congenital Trigger Thumbs
This will be a prospective study of all children ages 0 - 5 years old at the time of entry into the study that meet the inclusion criteria who present with congenital trigger thumb.
- Trial name
- NCT01424995
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- University of Utah
Newly Diagnosed Hormone Positive Clinical Stage 1 or 2 Breast Cancer
Preoperative Window of Endocrine Therapy Provides Information to Increase Compliance
The purpose of the study is to see if tumors respond to endocrine therapy by taking a total of 21 doses of Tamoxifen before and after surgery.
- Trial name
- POWER PIINC (NCT01614210)
- Testing
- Tamoxifen, Breast cancer surgery
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Utah
Autistic Disorder
Social Skills in Children With ASD and Process Drama
This is a one-group, pre-post feasibility study of an intensive, interdisciplinary (theatre, Occupational Therapy (OT), and Speech Language Pathology (SLP)) intervention targeted at social skill development in children, aged 3-4.
- Trial name
- NCT02850666
- Testing
- Interdisciplinary process drama
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Utah
Blood Transfusion, Autologous, Blood Doping
Detecting Autologous Transfusion by Measuring Alterations in the Dynamics of Red Blood Cell Maturation and Recycling
A total of 40 subjects will be recruited for participation in this study. 20 subjects (10 males and 10 females) will be randomized to the active group (those receiving re-infusion of autologous blood) and 20 subjects (10 males…
- Trial name
- NCT02684747
- Testing
- Autologous Transfusion
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Utah
Dominantly Inherited Stargardt's Disease (STGD3)
DHA Supplementation in Patients With STGD3
We have found that biomarkers of long-term elevated dietary intake of omega-3 fatty acids such as DHA and EPA are inversely associated with severity of disease phenotype in STGD3 patients.
- Trial name
- NCT00420602
- Testing
- Over the counter DHA/EPA dietary supplementation
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Stress Disorders, Post-Traumatic
Mind-Body Intervention for Veterans With PTSD
This pilot project evaluates the efficacy of a mind-body awareness training intervention, Mind-Body Bridging (MBB), in veteran patients with PTSD and comorbid symptoms.
- Trial name
- NCT02224989
- Testing
- Mind-Body Bridging
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Neurofibromatosis Type 1
Spinal Abnormalities in Neurofibromatosis Type 1 (NF1)
The purpose of this study is to determine the incidence and clinical history of neurofibromatosis type 1-related spinal abnormalities.
- Trial name
- Spine (NCT00844129)
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Utah
Bioavailability
Oxandrolone in Healthy Adults: A Relative Bioavailability Study
To assess the pharmacokinetics and relative bioavailability of a single dose of approximately 0.1 mg/kg of a medium chain triglyceride (MCT) oil oxandrolone solution vs. tablets in a small cohort of healthy adults.
- Trial name
- NCT03218631
- Testing
- Oxandrin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Utah
Peripheral Neuropathy, Obesity
The Effect of Bariatric Surgery on Peripheral Nerve Function and Axonal Regeneration
The goal of this research is understand if obesity is a major factor for neuropathy development in patients with and without Type 2 diabetes.
- Trial name
- BAR (NCT02218866)
- Where
- United States
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-traumatic Stress Disorder
PTSD Prevention Study Examining the Efficacy of Sertraline in Burn Victims
This is a randomized, double-blind, placebo-controlled study to determine whether administration of sertraline to patients who exhibit acute stress disorder secondary to severe burns can contribute to the prevention of…
- Trial name
- NCT02520726
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Obesity, Venous Thrombosis
Study to Evaluate Weight-based Enoxaparin Dosing in Obese Medical Patients at Risk for DVT
Deep vein thrombosis(DVT) is a common complication in hospitalized medical patients. Consensus guidelines recommend using medications such as heparin or low-molecular-weight heparins (LMWH) to prevent DVT in these patients.
- Conditions
- Obesity, Venous Thrombosis, Anticoagulants
- Trial name
- NCT00585182
- Testing
- Enoxaparin 0.5 mg/kg once daily
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of Utah