Clinical trials: sponsored by University of Utah
BRAFV600 Mutation, Stage IV Melanoma
Radiation Use During Vemurafenib Treatment
Patients are being asked to take part because they have melanoma that has spread to other organs in their body (metastatic). As part of this study, patients will receive radiation therapy and an approved drug (Vemurafenib).
- Trial name
- NCT01843738
- Testing
- Radiation therapy, Vemurafenib
- Where
- United States
- Sponsor
- University of Utah
Breast Cancer, Reconstructive Surgery
The BREASTrial:Breast Reconstruction Evaluation Using Acellular Dermal Matrix as a Sling Trial
Primary Hypothesis: 1. Alloderm and Dermamatrix have comparable complication rates when used for staged breast reconstruction Secondary hypotheses: 1.
- Trial name
- NCT00872859
- Testing
- Implantation of Dermal Matrix substitute
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of Utah
Contraception
Group Versus Individual Contraceptive Counseling for Resettled African Refugee Women
To evaluate the feasibility and effectiveness of group contraceptive counseling on family planning knowledge acquisition, service satisfaction, method uptake and continuation among a group of resettled African refugee women.
- Trial name
- NCT02796586
- Testing
- Counseling
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Utah
Bereavement, Death
An Individualized Grief Intervention for Spouses of Cancer Patients After the Patient's Death
Individuals providing end-of-life caregiving to partners with terminal cancer often begin the bereavement process before the patient dies and with additional sources of stress.
- Conditions
- Bereavement, Death, Cancer
- Trial name
- DPM (NCT02112084)
- Testing
- Individualized DPM
- Where
- United States
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University of Utah
Death, Cancer
Hospice and End-of-life Symptom Monitoring & Support Using an Automated System Designed for Family Caregivers
Improving end-of-life care and the suffering caused by poorly controlled symptoms is an important public health concern. The development of an automated telephone symptom monitoring and support system that assists caregivers in…
- Trial name
- SCP (NCT02112461)
- Testing
- SCP-Hospice Alert
- Where
- United States
- Volunteers
- 365 people
- Sponsor
- University of Utah
Stroke
Midodrine for Ischemic Stroke With Penumbra
Acute ischemic stroke (AIS) affects over 700,000 Americans every year and is the leading cause of long-term disability. Early neurological deterioration after AIS typically occurs within 72 hours of stroke onset and affects 30%…
- Trial name
- MISP (NCT02383121)
- Testing
- Midodrine
- Where
- United States
- Sponsor
- University of Utah
Major Depressive Disorder
Creatine Treatment for Female Adolescents With Depression Who Are Non-Responders to Fluoxetine or Escitalopram
The purpose of this study is to see if creatine, which is a naturally occurring chemical in the body, is effective for treating Major Depressive Disorder (MDD) in female teenagers.
- Trial name
- NCT00851006
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Utah
Congenital Heart Disease
Antiplatelet Activity of Aspirin in Infants After Aortopulmonary and Cavopulmonary Shunts
Background: Blood clots cause poor outcomes, including death, in babies with heart defects that require a surgical connection ("shunt") to provide blood flow to their lungs.
- Trial name
- NCT01656993
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Utah
Physical Exertion
Measuring Ability of Healthy Volunteers to Power a Bicycle-powered Oxygen Concentrator
The investigators would like to test how well healthy human volunteers power a modified oxygen concentrator. The investigators modified the oxygen concentrator to be powered by a bicycle instead of wall power so that it can be…
- Trial name
- NCT02909738
- Testing
- Volunteer to pedal a bicycle
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Insomnia
Sleep Management in Cancer Survivors
The pilot project will investigate three short-term intervention programs for sleep management in cancer survivors in a randomized controlled clinical study. Three programs to be examined in the study are: 1.
- Trial name
- NCT00935376
- Testing
- Sleep Education Program, Mind-Body Bridging Program, Mindfulness Meditation Program
- Where
- United States
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- University of Utah
Soft Tissue Sarcoma
Amrubicin Chemotherapy as First Line in Metastatic or Unresectable Soft Tissue Sarcoma
Primary Objectives 1. To evaluate the Response Rate (RR) for amrubicin in patients with metastatic or advanced sarcoma as first line therapy. 2. To evaluate Progression Free Survival (PFS). Secondary Objectives 1.
- Trial name
- ARSARC-PI-0010 (NCT01259375)
- Testing
- Amrubicin
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- University of Utah
Single Ventricle
Effect of Tadalafil on Exercise Capacity in Pediatric Fontan Patients
This pilot study is aimed at assessing the short-term effects of Tadalafil on the hemodynamic response to exercise and exercise capacity in patients with Fontan circulation.
- Trial name
- NCT01291069
- Testing
- Tadalafil Citrate, Sugar pill
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Pregnancy, Influenza
Maternal Immunization: Giving Immunity For Tomorrow
Study objectives are to compare influenza antibody levels in infant sera and maternal colostrum or breast milk at delivery, 2, and 6 months women who receive influenza immunization in early pregnancy, late pregnancy, or no…
- Trial name
- MI GIFT (NCT01496079)
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- University of Utah
Up-to-date Immunization Status for Children in Child Care
Immunization Protection in Child Care (IPiCC) Project
Ensuring that all children are fully immunized against vaccine-preventable diseases is a critical public health issue. Child care programs are critical targets for efforts to increase the proportion of infants and young children…
- Trial name
- IPiCC (NCT01773759)
- Testing
- Intervention child care programs
- Where
- United States
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cancer, Brain Cancer
Combination of Hydroxyurea and Verapamil for Refractory Meningiomas
Meningiomas account for 20% of primary adult brain tumors, occurring at an annual incidence of 6 per 100,000 (Louis, Scheithauer et al. 2000).
- Conditions
- Cancer, Brain Cancer, Meningioma
- Trial name
- NCT00706810
- Testing
- Hydroxyurea, Verapamil
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Utah
Major Depressive Disorder, Bipolar Disorder
Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel
Depression and bipolar disorder are major public health concerns for adolescents today. Teenage depression and bipolar disorder are associated with social isolation, family stress, school failure, substance abuse and suicide.
- Conditions
- Major Depressive Disorder, Bipolar Disorder, Serum Biomarkers
- Trial name
- NCT01957501
- Testing
- MDDScoreTM
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Cancer
RAD001, FOLFOX and Bevacizumab in Treatment of Colorectal Carcinoma
RAD001 (everolimus) is a novel oral derivative of rapamycin. RAD001 has been in clinical development since 1996 as an immunosuppressant in solid organ transplantation and has obtained marketing authorization (Certican®) for…
- Trial name
- NCT01047293
- Testing
- RAD001, FOLFOX, Bevacizumab
- Where
- 2 sites in United States
- Volunteers
- 47 people
- Sponsor
- University of Utah
Cancer, Melanoma
Radiation Therapy and Concurrent Cisplatin Chemotherapy for Locally Advanced or Metastatic Malignant Melanoma
The study is a prospective phase II trial of radiation therapy concurrent with cisplatin chemotherapy in the treatment of locally advanced or metastatic melanoma in patients who are deemed to require radiation therapy by treating…
- Trial name
- NCT00707161
- Testing
- Radiation Therapy, Cisplatin, Surgical resection
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Utah
Stages II-III Breast Cancer
Study of Neoadjuvant Chemotherapy With Nanoparticle Albumin Bound Paclitaxel, Doxorubicin and Cyclophosphamide (NAC) in Patients With Stages II-III Breast Cancer
The purpose of this clinical trial is to test whether treatment of patients with breast cancer with the combination of Abraxane (nab-paclitaxel), Adriamycin (doxorubicin), and Cyclophosphamide prior to surgery is safe and results…
- Trial name
- NAC (NCT01090128)
- Testing
- Nanoparticle Albumin Bound Paclitaxel, doxorubicin, cyclophosphamide
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Utah
Primary Insomnia, Secondary Insomnia
Two Contrasting Interventions for Sleep Management
This study will determine whether Mind-Body Bridging (MBB), a mindfulness training program is more effective than a common sleep medication, Zolpidem, in treating insomnia.
- Trial name
- NCT01804036
- Testing
- Zolpidem, Mind-Body Bridging
- Where
- 2 sites in United States
- Volunteers
- 72 people
- Sponsor
- University of Utah