Clinical trials: sponsored by University of Utah
Healthy
Nutrient Regulation of Amino Acid Transporters in Aging Human Skeletal Muscle
The goal of the research project is to determine how aging and inactivity reduce the muscle anabolic effect of nutrients and lead to muscle and functional loss.
- Trial name
- NCT01669590
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Utah
Anger, Hostility
Two Anger Management Programs for Teens.
The general aim of the proposed pilot study is to evaluate the the efficacy of mind-body bridging (MBB) for anger management compared with the Real Deal anger management program, in helping adolescents control or reduce their…
- Conditions
- Anger, Hostility, Aggression
- Trial name
- NCT02001246
- Testing
- Real Deal program for Anger Management, Mind-body Bridging (MBB) program
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- University of Utah
Neuro Developmental Delay
Heart Rate Variability in Children Conceived Via Assisted Reproductive Technologies
This is a proof of principle study that investigates heart rate variability differences in fetal and neonatal life in a longitudinal study design and compares two subject groups, offspring conceived using in-vitro fertilization…
- Trial name
- HRV ART (NCT00993369)
- Testing
- Holter monitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Utah
Sepsis, Systemic Inflammatory Response Syndrome
Effect of Education on Resident Physician Knowledge of Sepsis
A questionnaire was provided, including clinical vignettes and free text answers, to assess and evaluate the ability of resident physicians to identify systemic inflammatory response syndrome (SIRS), sepsis, and severe sepsis.
- Trial name
- NCT02927054
- Testing
- Sepsis Education
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- University of Utah
Chronic Kidney Disease, Diabetes
Effects of Febuxostat on Adipokines and Kidney Disease in Diabetic Chronic Kidney Disease
Hyperuricemia is emerging as a risk factor for development of diabetes and metabolic syndrome. Recently, it was shown in in-vitro cell culture experiments that hyperuricemia induces redox-dependent signaling and oxidative stress…
- Trial name
- NCT01350388
- Testing
- Febuxostat
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Utah
End Stage Renal Disease
Effect of Adipokines in Hemodialysis Patients
This is a double blinded randomized clinical trial of pioglitazone vs. placebo in overweight or obese, diabetic and non-diabetic hemodialysis patients.
- Trial name
- NCT01301027
- Testing
- Pioglitazone
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Utah
KRAS and NRAS Wild-type Colorectal Cancer
Regorafenib + Panitumumab for Colorectal Cancers
Evaluate the safety of regorafenib and panitumumab
- Trial name
- NCT02199223
- Testing
- regorafenib + panitumumab
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- University of Utah
Dyslipidemia
Study of Trilipix Effects on Lipids and Arteries
Fibrates reduce atherosclerosis and cardiovascular disease events. A major mechanism of this benefit appears to be their ability to raise plasma high density lipoprotein cholesterol (HDL-C), especially in patients with high…
- Trial name
- NCT01025492
- Testing
- Trilipix
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Utah
Healthy
Evaluation of Information Displays-A Paper, Computer and Simulator Based Study
Our objective is to develop intuitive, meaningful and ergonomically efficient informative displays specific to the user's domain.
- Trial name
- NCT00714012
- Testing
- observational
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Utah
Recovery From Anesthesia
Improved Patient Recovery After Anesthesia
The proposed study will measure the incidence of adverse events and the decrease in time to meet discharge criteria from the post anesthesia care unit when hypercapnic and hyperpnoea are used during emergence.
- Trial name
- NCT01477398
- Testing
- QED-100
- Volunteers
- 31 people
- Sponsor
- University of Utah
Arthroscopic Iliopsoas Release
Functional Implications of Arthroscopic Iliopsoas Release
The purpose of this study is to investigate the functional effects of arthroscopic iliopsoas release. To complete this aim, we will recruit patients who have undergone arthroscopic iliopsoas release by Dr. Aoki.
- Trial name
- NCT01763372
- Volunteers
- 36 people
- Sponsor
- University of Utah
Major Depressive Disorder
Creatine Augmentation in Veterans With SSRI-Resistant Major Depression
The purpose of this study is to determine whether creatine will be helpful as an adjunctive treatment for treatment-resistant major depressive disorder (MDD) in female and male Veterans.
- Trial name
- NCT01175616
- Testing
- Creatine
- Sponsor
- University of Utah
Recurrent Pregnancy Loss, Miscarriage
Hydroxychloroquine (HCQ) for Recurrent Pregnancy Loss
Recurrent pregnancy loss (RPL) affects 5% of couples trying to achieve parenthood. Most cases of RPL are unexplained and have no effective treatment to improve the likelihood of a pregnancy resulting in a live birth.
- Trial name
- NCT02379650
- Testing
- Hydroxychloroquine (HCQ)
- Where
- 2 sites in United States
- Sponsor
- University of Utah
Inflammation, Insulin Resistance
Ergocalciferol Therapy in Calcidiol Deficient, Hemodialysis Patients on Therapeutic Doses of Paricalcitol
The objective of this study is to determine the effects of cholecalciferol treatment on inflammation and insulin resistance, in patients on hemodialysis that are previously treated with paricalcitol.
- Trial name
- NCT02011828
- Testing
- Ergocalciferol
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Utah
End Stage Renal Disease
Protein, Nutrition and Cardiovascular Disease in Stage 5 Chronic Kidney Disease
National Kidney Foundation guidelines recommend a dietary protein intake of 1.2 grams per kilogram per day (g/kg/d) in hemodialysis patients.
- Trial name
- NCT00566670
- Where
- 2 sites in United States
- Volunteers
- 145 people
- Sponsor
- University of Utah
Bone Marrow Transplant
Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplant
This is a prospective observational study to determine the point after bone marrow transplant in adults and children at which the neutrophils derived from the transplanted stem cells are competent to form functional neutrophil…
- Trial name
- NCT01735565
- Where
- 3 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Utah
Hemodialysis
Dialysis Registry in Utah
Based on the Medicare data, the 5-year survival of dialysis patients is only 39%. This is lower than that of stage IIIB breast cancer (54% 5-year survival).
- Trial name
- NCT02023528
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- University of Utah
Kidney Disease
Effects of High Dietary Fiber Supplementation in Diabetic Chronic Kidney Disease
Loss of kidney function results in accumulation in the blood of molecules that are either excreted or metabolized by the kidney. Collectively, these molecules are termed Uremic Retention Molecules (URMs) or toxins.
- Trial name
- NCT01838330
- Testing
- psyllium
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Persian Gulf War Syndrome in Veteran
Gulf War 1 Veteran Healthcare Satisfaction
The purpose of this study is to investigate Gulf War 1 Veteran (GW1V) patient perceptions of, and satisfaction with, their VA primary care treatment, and physician effectiveness in delivering improved point of service, in the…
- Trial name
- NCT01703767
- Testing
- Provider Education Workshop
- Where
- 2 sites in United States
- Sponsor
- University of Utah
End Stage Renal Disease
Protein Supplementation in Dialysis Patients
Poor nutritional status as evidenced by low body mass index, low muscle mass or low serum albumin is a strong predictor of morbidity and mortality in dialysis patients.
- Trial name
- NCT01855295
- Testing
- Protein Supplement
- Volunteers
- 73 people
- Sponsor
- University of Utah