Clinical trials: sponsored by University of Utah
Hypertension, Vitamin D Deficiency
Effects of Vitamin D on Renin Expression in Hypertensive Patients
The cardiovascular effects of vitamin D therapy (in humans) have been documented only in patients with known vitamin D deficiency or hyperparathyroidism (a surrogate marker of inadequate vitamin D activity).
- Trial name
- NCT00585442
- Testing
- calcitriol
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Esophagitis
A Pilot Study of the Treatment of Eosinophilic Esophagitis With Omalizumab
Eosinophilic esophagitis (EE) is an increasingly recognized condition characterized by dysphagia, food impaction or other obstructive esophageal symptoms in children and young adults.
- Trial name
- NCT00123630
- Testing
- omalizumab
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Tourette Syndrome
MRI Study of Tic Remission in Tourette Syndrome
Doctors provide a ray of hope to children and their parents with the knowledge that, for most patients, symptoms of Tourette syndrome improve by the time they are young adults.
- Trial name
- NCT01405859
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Utah
Improved Intraoperative Blood Loss Estimates
Method for Improved Intraoperative Blood Loss Estimates
The purpose of this study is to develop a mathematical algorithm which the investigators plan to use to more accurately estimate intraoperative blood loss.
- Trial name
- EBL (NCT01634828)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Utah
Kidney Transplantation
Pharmacokinetic Profile of Myfortic in Combination With Tacrolimus in Fed Versus Fasting State
Literature regarding the effect of food on the pharmacokinetic (PK) profile of enteric-coated mycophenolate sodium combined with tacrolimus and corticosteroid withdrawal is lacking.
- Trial name
- NCT00585468
- Testing
- Myfortic
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Utah
Complications; Contraceptive, Female Lactation
Early Versus Standard Postpartum Insertion of the Etonogestrel Contraceptive Implant
A highly effective single rod contraceptive implant is now available for use in the US. Delays in the insertion of the device until later in the postpartum period may negatively impact initiation rates.
- Trial name
- NCT00847587
- Testing
- Etonogestrel contraceptive implant
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University of Utah
Breast Cancer, Ovarian Cancer
Risk Education and Assessment for Cancer Heredity
Individuals living in geographically underserved areas encounter considerable barriers to access of quality cancer genetic services.
- Conditions
- Breast Cancer, Ovarian Cancer, Genetic Predisposition
- Trial name
- REACH (NCT01346761)
- Testing
- Telephone Genetic Counseling, In-Person Genetic Counseling
- Where
- United States
- Volunteers
- 1,012 people, healthy volunteers welcome
- Sponsor
- University of Utah
Colorectal Cancer
Family Colorectal Cancer Awareness and Risk Education Project (Family CARE Project)
The Family Colorectal Cancer Awareness and Risk Education Project (Family CARE Project) is designed to determine whether a personalized telephone plus mailed print cancer risk assessment and behavior change counseling…
- Trial name
- Family CARE (NCT01274143)
- Testing
- TeleCARE, Pamphlet intervention
- Where
- 8 sites in United States
- Volunteers
- 496 people
- Sponsor
- University of Utah
Obesity, Oligospermia
Aromatase Inhibitors in the Treatment of Male Infertility
Obesity is associated with an increase in blood levels of estrogen. Estrogen or "female hormone" is believed to have a negative effect on sperm production.
- Trial name
- NCT00440180
- Testing
- Anastrozole
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Utah
Kidney Transplantation
Study of Sodium Bicarbonate in Kidney Transplant Recipients
The purpose of this study is to compare the effect of sodium bicarbonate versus no sodium bicarbonate treatment on urinary ammonia levels and urinary transforming growth factor-beta1 (TGF-beta1) excretion in renal transplant…
- Trial name
- NCT01225796
- Testing
- Sodium bicarbonate
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Utah
Heart Failure
The Effect of Simvastatin Therapy on the Expression of Procoagulant and Inflammatory Markers in Heart Failure
Our proposed research will examine whether treatment with simvastatin alters expression and activity of monocyte TF, whether polymorphisms in the TF gene alter the therapeutic effect and what effect treatment has on inflammatory…
- Trial name
- NCT00769210
- Testing
- Simvastatin
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Utah
Cardiovascular Disease
Study of the Cardiovascular Vitamin, CardioLife
Evaluation of the metabolic and physiological characteristics of patients with diagnosed Cardiovascular Disease following administration of the Cardiovascular vitamin, CardioLife.
- Trial name
- NCT02088307
- Testing
- CardioLife
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Utah
Primary Myelofibrosis, Primary Pulmonary Hypertension
Reversible Secondary Myelofibrosis or Clonal Myeloproliferative Disorder
To determine the prevalence of myelofibrosis in patients with primary pulmonary hypertension, and to discover if the fibrosis in these patients is primary (AMM) or secondary.
- Conditions
- Primary Myelofibrosis, Primary Pulmonary Hypertension, Secondary Myelofibrosis, Pulmonary Arterial Hypertension
- Trial name
- NCT00722254
- Where
- 2 sites in United States
- Volunteers
- 15 people
- Sponsor
- University of Utah
Bone Ingrowth, Pain
The Effects of Celecoxib on Bone Ingrowth
The purpose of this study is to evaluate the effect of Celebrex on bone growth into porous coated implants, following postoperative total knee arthroplasty administration of Celebrex for pain relief.
- Trial name
- NCT00585156
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Utah
Tibial Plateau Fracture
Continuous Femoral Nerve Block With a Tibial Plateau Fracture
The primary purpose of the proposed study is to compare postoperative pain scores and total opioid consumption between two groups randomized to either receive or not receive a femoral nerve block for pain control following…
- Trial name
- NCT02168959
- Testing
- bupivacaine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Utah
Infection
Bacterial Contamination of Operative Splash Basins
The primary objective of this study is to compare the efficacy of adding 0.05% chlorhexidine gluconate to the splash basin in reducing bacterial growth from splash basins at the end of a total joint replacement procedure.
- Trial name
- NCT02434510
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Utah
Blood Pressure
Predicting Blood Pressure in Patients Following Defibrillation
During tachyarrhythmias, central venous pressures increases while arterial blood pressure (BP) decreases. The result is mixed messages to the central nervous system.
- Trial name
- NCT02686307
- Testing
- ICD Implant
- Volunteers
- 33 people
- Sponsor
- University of Utah
Atrial Fibrillation
SOAR: Study Observing Antiarrhythmic Remodelling Using LGE-MRI
The primary objective of this study is to demonstrate how dronedarone (Multaq®) may aid in the slowing of progression of left atrial and ventricular fibrosis in patients with atrial fibrillation as assessed by late gadolinium…
- Trial name
- SOAR (NCT01182376)
- Testing
- dronedarone
- Volunteers
- 33 people
- Sponsor
- University of Utah
Hypertension, Dyslipidemia
Effects of Xoçai Antioxidant Supplements on Atherosclerosis Risk Factors
An antioxidant dietary supplement made from cocoa powder, and extracts of acai, grape and blueberry will be tested for effects on blood sugar, blood pressure, cholesterol and related parameters in human subjects.
- Conditions
- Hypertension, Dyslipidemia, Hyperglycemia
- Trial name
- NCT00666250
- Testing
- Xocai Activ drink
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Utah
Neonatal Screening
Parent Education and Choice About Newborn Screening and Bloodspot Retention
To address the content, timing, efficacy, and impact of prenatal education about newborn screening generally and sample retention specifically.
- Trial name
- NCT02676245
- Testing
- Viewing Newborn Screening movie, Viewing Residual Dried Blood Spot movie
- Volunteers
- 664 people
- Sponsor
- University of Utah