Clinical trials: sponsored by University of Utah
Obesity, Endothelial Dysfunction
Effects of Body Mass Index on the Hyperemic Response to Regadenoson
We will test the hypothesis that a single dose of Regadenoson will produce equivalent degrees of coronary hyperemia in patients of widely different body size.
- Conditions
- Obesity, Endothelial Dysfunction, Decreased Vascular Flow
- Trial name
- NCT00859833
- Testing
- Adenosine, Regadenoson
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Utah
Myelodysplastic Syndrome
The Role of Erythropoietin in Myelodysplastic Syndrome
The purpose of the study is to elucidate the causative molecular events responsible for the abnormal erythropoiesis in MDS.
- Trial name
- NCT00723112
- Where
- 2 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cataract
Prospective Evaluation of Safety and Efficacy of Two Forms of Corneal Stromal Hydration
The study objective is to compare traditional and Wong methods of wound hydration for wound sealing following cataract surgery.
- Trial name
- NCT00432874
- Testing
- wound hydration method
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Myopia
Comparison of LASIK and SBK
The objective of the study is to compare clinical outcomes from LASIK and SBK using FDA-approved laser technology on the same patient
- Trial name
- NCT00714363
- Testing
- LASIK, SBK
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Utah
Myopia
Comparison of Conventional and Custom Photorefractive Keratectomy (PRK)
The study objective is to compare the clinical outcomes using wavefront guided PRK with iris registration and conventional laser PRK using FDA-approved laser technology on the same patient.
- Trial name
- NCT00713856
- Testing
- Custom PRK with iris registration, Conventional PRK
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Utah
Myopia
Comparison of Photorefractive Keratectomy (PRK) and Sub-Bowman's Keratomileusis (SBK)
The objective of the study is to compare clinical outcomes from PRK and SBK using FDA-approved laser technology in the same patient
- Trial name
- NCT00714922
- Testing
- PRK, SBK
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Utah
Premature Infants
Urine Concentration of S100B in Extremely Premature Infants
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study.
- Trial name
- NCT00747591
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- University of Utah
Preterm and Term Infants
Relationship of Gestational Age and Urine Concentration of S100B in Preterm and Term Infants in the First Week of Life
S100B, a calcium-binding protein, is found predominantly in the central nervous system (CNS) and is increased in CSF and blood after CNS injury. There are two objectives to this study.
- Trial name
- NCT00747864
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- University of Utah
Post-Hemorrhagic Hydrocephalus
Cerebral Perfusion, Oxygenation, Electrical Activity
The specific aim of the research proposal in preterm infants with IVH and PHH who require placement of an Omaya reservoir or a shunt is to determine if decreasing ventricular volume improves, middle cerebral artery flow, cerebral…
- Trial name
- NCT00747682
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Bronchopulmonary Dysplasia
Neonatal Intensive Care (NICU) Course and Hospital Outcome of Infants With BPD Treated Using Inhaled Nitric Oxide
This is a chart review study of neonates admitted to Primary Children's Medical Center or University of Utah NICU who had or developed a diagnosis of bronchopulmonary dysplasia (BPD) and were treated for this condition with…
- Trial name
- NCT00757146
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Utah
Stress Fractures, Bone Geometry
Bone Geometry, Strength, and Biomechanical Changes in Runners With a History of Stress Fractures
Stress fractures are a common and debilitating injury for a variety of athletes however current evidence does not clearly allow easy prediction of athletes at risk for a first fracture.
- Conditions
- Stress Fractures, Bone Geometry, Bone Strength, Biomechanical Changes
- Trial name
- NCT00766077
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Utah
Asthma, Mental Health
Electronic Pharmacotherapy Risk Management
The purpose of the Utah ePRM (electronic Pharmacotherapy Risk Management) project is to improve quality and safety of medication use while simultaneously controlling costs and detecting fraud and abuse.
- Conditions
- Asthma, Mental Health, Pain
- Trial name
- ePRM (NCT00828490)
- Testing
- provider feedback, patient intervention, Process-level
- Where
- United States
- Volunteers
- 174,000 people
- Sponsor
- University of Utah
Atelectasis
Does High Intraoperative Inspired Oxygen Reduce Postoperative Arterial Oxygen Saturation?
The purpose of this study is to determine whether breathing high levels of oxygen during surgery affects oxygen levels after surgery.
- Trial name
- NCT00715741
- Testing
- FiO2 (fraction of inspired oxygen) 0.3 plus PEEP (positive end expiratory pressure) 3 -5 cm water, FiO2 0.3 without PEEP, FiO2 >0.9 with 3-5 cm water PEEP
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Utah
Intra-Abdominal Hypertension
Intra-Abdominal Hypertension in Neonatal Intensive Care Patients
The observational study is designed to determine the feasibility of performing Intra-Abdominal Pressure (IAP) via bladder pressure measurements and of tracking IAP in neonates who require bladder catheterization.
- Trial name
- NCT00747552
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Pain
Mind Engagement With Music for Nondrug Pain Relief
The purpose of this study is to determine whether engaging in music listening tasks can reduce the perception of pain and provide nondrug pain relief.
- Trial name
- NCT00103870
- Testing
- Electrodermal stimulation, Music listening task
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Utah
Myelofibrosis
Bone Marrow Transplant Chart Review for RIC
We will evaluate the records of 30 patients that have undergone allogeneic transplant, specifically looking at engraftment rate, relapse rate, disease free survival, overall survival, causes of death and other pertinent…
- Trial name
- NCT00723333
- Testing
- Reduced Intensity Conditioning (RIC) Allogenic Transplant
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Heart Failure
Tissue Factor Expression in Stage C Heart Failure
Monocyte tissue factor (TF) was characterized in Class C heart failure (HF) vs. 25 age-matched volunteers. TF was 2.9 fold higher (p < 0.001) in HF patients vs. controls.
- Trial name
- TFHF (NCT00935740)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of Utah
Insomnia
Pilot Study on Sleep Management for US Veterans
The aim of the proposed pilot study is to scientifically evaluate the use of Mind-Body Bridging Program (MBBP) as an effective intervention for improving health outcomes in veterans exhibiting sleep disturbance in the Primary…
- Trial name
- NCT00933959
- Testing
- Mind-Body Bridging Program, Sleep Hygiene
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Utah
Cystic Fibrosis
Study of Hepatic Glucose Production and De Novo Lipogenesis in Patients With Cystic Fibrosis
OBJECTIVES: I. Determine the amount of hepatic glucose production derived from gluconeogenesis and glycogenolysis in the post-absorptive state in patients with cystic fibrosis. II.
- Trial name
- NCT00014781
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Utah
Hereditary Elliptocytosis (HE), Hereditary Pyropoikilocytosis (HPP)
A Novel Mutation of the Spectrin Gene
The purpose of this study is to find a gene or its mutation (an altered gene) that puts individuals at risk for developing HE or HPP.
- Trial name
- NCT00723567
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Utah