Clinical trials: sponsored by University of Valencia
Lumbar Disc Degeneration, Lumbar Disc Disease
Total Lumbar Disc Prosthesis and Subsequent Work Activity at at Least Five Years After Total Lumbar Disc Replacement
Lumbosciatica is a very prevalent pathology. When conservative treatments fail, surgery should be considered. The traditional surgical treatment is lumbar arthrodesis.
- Conditions
- Lumbar Disc Degeneration, Lumbar Disc Disease, Sciatica, Lumbar Disc Herniation
- Trial name
- NCT06989632
- Testing
- Total lumbar disc prosthesis (Baguera®L, Spineart, Switzerland)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- University of Valencia
Smokers
Immediate Effects of Mental Practice and Therapeutic Exercise in Mild Smokers
The goal of this clinical trial is to learn about the effects who would add mental practice based on action observation to a therapeutic exercise program in young mild smokers.
- Trial name
- NCT06108323
- Testing
- Theapeutic exercise plus action observation training
- Where
- Spain
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Prodromal Alzheimer's Disease
Combined tDCS and Cognitive Training in Alzheimer's
The General Objective of the study is to evaluate the short- and long-term efficacy of combining transcranial Direct Current Stimulation (tDCS) and cognitive training (CT) in patients with mild cognitive impairment due to…
- Trial name
- COMBINA-COG (NCT06861231)
- Testing
- Transcraneal Direct Current Stimulation (tDCS)- Active, Cognitive Training (CT)
- Where
- Spain
- Volunteers
- 22 people
- Sponsor
- University of Valencia
Alzheimer Disease (AD), Unwanted Loneliness
Intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer
The absence of social relationships negatively affects physical, psychological, and social health. In other words, it alters people's quality of life and makes active aging difficult.
- Conditions
- Alzheimer Disease (AD), Unwanted Loneliness, Family Caregivers, Living With Process
- Trial name
- NCT07639645
- Testing
- Multimodal intervention to Reduce Unwanted Loneliness in Family Caregivers of People With Alzheimer
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Valencia
Subacromial Pain Syndrome
Transcranial Electrical Stimulation in Subacromial Pain Syndrome
The goal of this clinical trial is to analyze whether a physiotherapy protocol based on strengthening exercises to the shoulder girdle muscles carried on during anodal transcranial electrical stimulation (a-TES) is more effective…
- Trial name
- NCT05951933
- Testing
- Strenghtening + TES
- Where
- Spain
- Sponsor
- University of Valencia
Autism Spectrum Disorder, Attention Deficit Hyper Activity
Digital-based Psychosocial Intervention for Parents of Children With Neurodevelopmental Disorders
The goal of this clinical trial is to implement a structured psychosocial intervention program with digital support (randomized and with a control group) that will be conducted virtually and synchronously to families of children…
- Trial name
- INPSYD (NCT06303791)
- Testing
- Digital Psychosocial intervention
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- University of Valencia
Healthy Adult
Safety and Effects of High-Intensity Blood Flow Restriction Training in the Rotator Cuff
This study aims to analyze the effects of an 8-week strength training program combining different exercise intensities and blood flow restriction (BFR) conditions on safety, tolerability, muscle adaptations, and physical…
- Trial name
- NCT07404683
- Testing
- High-intensity exercise with BFR, Low-intensity exercise with BFR, High-intensity exercise without BFR
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Loneliness, Mental Health Disorder
A Multimodal Intervention for Community-dwelling Individuals With Unwanted Loneliness
The absence of social relationships negatively affects physical, psychological, and social health. In other words, it alters people's quality of life and makes active aging difficult.
- Trial name
- NCT06382181
- Testing
- Music therapy for community-dwelling individuals with unwanted loneliness, Health education for community-dwelling individuals with unwanted loneliness, Physical exercise for community-dwelling individuals with unwanted loneliness
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- University of Valencia
Severe Knee Osteoarthritis
Acute Effects of Blood Flow Restriction Training to Failure on Hypoalgesia in Patients With Severe Knee Osteoarthritis Using Dynamic or Fixed Occlusion Pressure
This study aims to compare the acute effects on hypoalgesia of training to failure using blood flow restriction (BFR) with dynamic occlusion versus BFR with fixed occlusion in patients with severe gonarthrosis.
- Trial name
- NCT07300384
- Testing
- Low-intensity resistance exercise to failure with moderate arterial occlusion pressure and dynamic pressure., Low-intensity resistance exercise to failure with moderate arterial occlusion pressure and fixed pressure.
- Where
- 2 sites in Spain
- Volunteers
- 45 people
- Sponsor
- University of Valencia
Severe Knee Osteoarthritis
Acute Exercise Responses With Blood Flow Restriction Under Dynamic Pressure Compared to Fixed Pressure in Patients With Severe Gonarthrosis
This study aims to evaluate the acute effects of blood flow restriction (BFR) training on hypoalgesia and neuromuscular responses in patients with severe gonarthrosis by comparing the application of pressure with a dynamic versus…
- Trial name
- NCT07316933
- Testing
- Low-intensity resistance exercise with moderate arterial occlusion pressure and dynamic pressure., Low-intensity resistance exercise with moderate arterial occlusion pressure and fixed pressure., Moderate-intensity resistance exercise with low arterial occlusion pressure and dynamic pressure.
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- University of Valencia
Acute Effects of Exercise in Healthy People, Health Adult Subjects
Acute Effects of Aerobic Exercise and High-intensity Interval Exercise With Immersive Virtual Reality
This study aims to compare the acute effects at the cardiovascular (heart rate, blood pressure) and physiological (lactate) levels, as well as the perception of effort and fatigue, of four exercise modalities, one based on the…
- Trial name
- NCT07101341
- Testing
- Traditional aerobic training, High Intensity Interval Training (HIIT), Aerobic training performed with a immersive virtual reality application
- Where
- Spain
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Rotator Cuff Related Shoulder Pain
Effects of a 4-week Low-intensity Training With Blood Flow Restriction in People With Rotator Cuff-related Shoulder Pain
This study aims to analyze the effects of 4 weeks of low-intensity exercise with and without blood flow restriction (BFR) on pain, fear of movement, catastrophizing about pain, strength, and disability in a population with…
- Trial name
- NCT07324993
- Testing
- Resistance exercise with BFR, Resistance exercise without BFR
- Volunteers
- 34 people
- Sponsor
- University of Valencia
Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs
Peri-implant Tissues Changes for Different Abutment Shapes and Heights
The goal of this randomized clinical trial is to investigate the influence of supracrestal soft tissue on abutments of different heights (2-mm vs. 3-mm) and shapes (cylindrical abutment vs.
- Conditions
- Dental Implant-Abutment Designs, Marginal Bone Loss in Different Abutment Designs, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- NCT07509281
- Testing
- Bone-Level Implant Placement with Transmucosal Abutment and One Abutment-One Time Protocol
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Tooyh Discoloration
Impact of At-Home Dental Bleaching on Quality of Life Using OHIP-14
This prospective clinical study aims to evaluate the clinical efficacy of an at-home dental bleaching protocol and its impact on oral health-related quality of life using objective color measurements and patient-reported…
- Trial name
- WID-OHIP (NCT07624344)
- Testing
- Carbamide peroxide 16%
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Diabetic Complications, Foot Care
Evaluation of Materials for the Distribution of Pressure in the Treatment of Neuroischemic Ulcers
The hypothesis of this study is based on the premise that pressure-distributing materials with superior biomechanical and tissue response properties will be capable of improving the healing rate of neuropathic ulcers.
- Trial name
- NCT07620379
- Testing
- felt padding
- Where
- Spain
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Relatives
"Family Connections" for Caregivers of People With Eating Disorders and Personality Disorders.
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with eating disorders and personality disorders in a randomized control trial with a Spanish participants.
- Trial name
- FC-ED&PD (NCT05404035)
- Testing
- Family Connections for relatives of people with eating disorders and personality disorders, Optimized Treatment As Usual
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Relatives
Family Connections Transdiagnostic for Relatives of People With Emotional Dysregulation
The aim of this study is to evaluate the efficacy of the Family Connections Transdiagnostic (FC-T) program in relatives of individuals with psychological disorders associated with emotional dysregulation through a randomized…
- Trial name
- FC-T (NCT07585955)
- Testing
- Family Connections Transdiagnostic for relatives of people with emotional dysregulation, Optimized Treatment as Usual (TAU-O)
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- University of Valencia
Aging, Physical Activity
NEUROmuscular Training for Enhanced AGE Longevity
In recent years the research group on Prevention and Health in Exercise and Sport (PHES) has carried out numerous studies that have provided current and convincing evidence of the benefits of physical activity and exercise for…
- Conditions
- Aging, Physical Activity, Training
- Trial name
- NEUROAGE (NCT06620666)
- Testing
- Water-based power resistance training + Dietary supplement I (WPowDSI), Elastic band-based power resistance training + Dietary supplement I (EBPowDSI), Elastic band-based eccentric resistance training + Dietary supplement II (EBEccDSII)
- Where
- Spain
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Relatives
Family Connections for Caregivers of People With Suicidal Behavior
The aim of our study is to verify the efficacy of the Family Connections intervention for relatives of people diagnosed with suicidal behavior disorder in a randomized control trial with a Spanish participants.
- Trial name
- NCT05157607
- Testing
- Family Connections Protocol for Relatives of Patients with SBD., Treatment as Usual Optimized Protocol (TAU-O)
- Where
- Spain
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Cancer
Spanish Meaning-Centered Psychotherapy for Cancer
The aim of this study is to verify the efficacy of the Spanish adaptation of Meaning-Centered Psychotherapy for Spanish participants with cancer in a randomized control trial.
- Trial name
- NCT05197348
- Testing
- Meaning-Centered Group Psychotherapy (MCP)., Cognitive Behavioral Psychotherapy (CBT).
- Where
- Spain
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- University of Valencia