Clinical trials: sponsored by University of Virginia
Lung Cancer
Post-Treatment Surveillance in Lung Cancer
There are 13.7 million Americans currently living with a history of cancer. With continued improvements in cancer treatment and increasing life expectancy, this number is expected to reach nearly 18 million within the next…
- Trial name
- NCT03475420
- Volunteers
- 9,613 people
- Sponsor
- University of Virginia
Non-Small-Cell Lung Cancer
Lung Cancer Information Study (LCIS-R01)
The primary specific aim is to test the hypothesis that use of a decision aid to enhance informed, shared decision making coupled with quality of life assessment in patients with advanced lung cancer receiving first-, second-, or…
- Trial name
- LCIS-R01 (NCT01924416)
- Testing
- Enhanced Care (intervention group and comparison group), Usual care (routine chemotherapy cycles and imaging studies)
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- University of Virginia
HIV Infections
Text Messaging Intervention to Improve HIV Adherence in Rural Drug Users
The investigators will develop and test the feasibility and promise of a combined HIV adherence assessment and intervention application for rural drug users using an available, familiar technology whose reach will grow…
- Trial name
- TEXTR34 (NCT01343654)
- Testing
- Text messaging plus EMA, Treatment as usual
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Virginia
Patellofemoral Pain Syndrome
Rehabilitation With Patterned Electrical Neuromuscular Stimulation for Patients With Patellofemoral Pain
This is a Randomized Controlled Trial (RCT) regarding the conservative treatment of patellofemoral pain (PFP) with an impairment based rehabilitation program.
- Trial name
- PENS for PFP (NCT02441712)
- Testing
- PENS
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Virginia
Type 1 Diabetes Mellitus
Feasibility and Efficacy of Delivering Blood Glucose Awareness Training Over the Internet
BGATHome is an interactive, web-based training program designed to improve the ability of adults with Type 1 Diabetes to recognize, predict, treat, and avoid extreme blood glucose (BG) events.
- Trial name
- NCT00327210
- Testing
- Blood Glucose Awareness Training
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- University of Virginia
Amebiasis, Cryptosporidium
Field Studies of Amebiasis in Bangladesh
The purpose of this study will be to investigate the incidence of both Amebiasis and cryptosporidiosis in Bangladeshi children and examine genetic variation in innate and adaptive immunity with respect to these infections.
- Trial name
- NCT02734264
- Where
- Bangladesh
- Volunteers
- 629 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Behavioral and Psychiatric Symptoms of Dementia, Dementia
Behavioral and Environmental Sensing and Intervention
This 3-phase research plan to employ Behavioral and Environmental Sensing and Intervention (BESI) will overcome the fundamental scientific barriers to realizing prediction of agitation episodes and detection early stages of…
- Conditions
- Behavioral and Psychiatric Symptoms of Dementia, Dementia, Caregivers
- Trial name
- BESI (NCT03297268)
- Testing
- Intervention with Home-Based Caregivers
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Peripheral Artery Disease
Comprehensive Magnetic Resonance of Peripheral Arterial Disease
The purpose of this study is to develop new ways of imaging fatty blockages in the leg arteries to improve upon techniques used now and to develop new ways of understanding how new treatments may affect the disease.
- Trial name
- NCT00587678
- Testing
- Simvastatin, Ezetimibe, Simvastatin/Ezetimibe
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- University of Virginia
Sports Related Concussion
The Impact of Riboflavin on the Severity and Duration of Sports Related Concussion
The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.
- Trial name
- NCT02235337
- Testing
- Riboflavin 400mg daily
- Where
- 2 sites in United States
- Volunteers
- 248 people
- Sponsor
- University of Virginia
Sports-related Concussion
The Impact of Riboflavin on Sports-related Concussion
The purpose of this study is to investigate the effectiveness of riboflavin to decrease the duration of time for a student-athlete to return to participation in sports after a sports related concussion.
- Trial name
- NCT02772237
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Diabetes Mellitus, Type 1
Closed-Loop Control in Young Children 5-8 Years Old Using DiAs Platform
The overall aim of this proposed research is to determine the safety, feasibility and efficacy (AP vs at home use of SAP) of the Diabetes Assistant (DiAs) controller in day and night closed-loop control in young children 5-8…
- Trial name
- NCT02750267
- Testing
- Diabetes Assistant (DiAs) with Closed-Loop
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Virginia
Alcohol Dependence, Binge Eating
Topiramate for the Treatment of Alcohol Dependent Binge-Eating Disordered Individuals
The purpose of this study is to test the feasibility of using topiramate to reduce binge eating and drinking episodes in alcohol dependent individuals with comorbid binge eating disorder.
- Trial name
- NCT00300742
- Testing
- Topiramate
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- University of Virginia
Health Behavior
Reduce African-American Infant Mortality
The overall purpose of this randomized trial is to develop and evaluate a systematic approach to improve African-American parental behaviors specifically with regards to the infant sleep environment.
- Trial name
- SIDS (NCT01361880)
- Testing
- Reduce Infant Mortality
- Where
- United States
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Glioblastoma
Stereotactic Radiosurgery With Nivolumab and Valproate in Patients With Recurrent Glioblastoma
The purpose of this study is to evaluate the safety and feasibility of the immunotherapeutic agent nivolumab given in combination with gamma knife therapy and valproate in patients with recurrent glioblastoma, a common and lethal…
- Trial name
- NCT02648633
- Testing
- Stereotactic Radiosurgery, Nivolumab, Valproate
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Virginia
Safety Issues, Tolerance
Safety and Tolerability of Lactoferrin/FOS in Very Low Birth Weight Infants
This study will examine the safety and tolerability of supplementation with bovine lactoferrin with fructo-oligosaccharide a simple sugar in very low birth weight infants.
- Conditions
- Safety Issues, Tolerance, Very Low Birth Weight Infant
- Trial name
- NCT03163212
- Testing
- Lactoferrin/FOS
- Volunteers
- 20 people
- Sponsor
- University of Virginia
Prostatic Hyperplasia, Prostate Cancer
Digital Rectal Exam Proficiency Tool
A digital rectal exam proficiency tool, titled the 'DiRECT' was developed based on the consensus of 10 experts. The purpose of this study is to validate this tool for use in both undergraduate and graduate medical education .
- Trial name
- DiRECT (NCT02278679)
- Testing
- Digital Rectal Exam
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- University of Virginia
Healthy, Physiology
Assessment of the Changes in Cortical and Medullary Renal Blood Flow During Exercise in Healthy Subjects Using Contrast Enhanced Ultrasound
Renal parenchymal blood flow can be divided in cortical and medullary blood flow. Changes and factors affecting renal medullary blood flow have not been studied in detail previously as investigators/doctors did not have tools to…
- Trial name
- NCT02672722
- Testing
- Definity, Exercise, Kidney Ultrasound
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Type 2 Diabetes
Effect of Angiotensin Converting Enzyme Inhibitor, Lisinopril, on Renal Blood Flow and Its Correlation With Proteinuria Reduction in Subjects With Type 2 Diabetes and Kidney Disease
The purpose of the study is to investigate the effect of a blood pressure medication, Lisinopril, or similar drugs in that class, on the flow of blood to the kidneys.
- Trial name
- NCT01101269
- Testing
- ACEI or ARB, Lisinopril
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Collapse of Thoracic Vertebra, Collapse of Lumbar Vertebrae
Study of Dexmedetomidine in Spine Surgery
The investigators will conduct a prospective randomized double blind study comparing methadone plus methadone and intraoperative dexmedetomidine in multi-level spine surgery in two randomized groups.
- Trial name
- NCT01850017
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Sinusitis, Nasal Polyps
Association of Periostin Levels and Chronic Sinusitis
The purpose of this study is to see if a protein in blood, called periostin, can determine if patients have chronic sinusitis. This protein is in everyone's body, but the level of the protein may indicate certain conditions such…
- Trial name
- NCT02071667
- Testing
- Blood draw
- Where
- United States
- Sponsor
- University of Virginia