Clinical trials: sponsored by University of Virginia
Alcohol Dependence
Ondansetron With Olanzapine for the Treatment of Alcohol Dependence: A Preliminary Clinical Trial
This study would like to test whether the combination of ondansetron and olanzapine will be superior to placebo at decreasing self-reported heavy drinking among early onset alcoholics.
- Trial name
- NCT00678457
- Testing
- Ondansetron, Olanzapine
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Virginia
Diarrhea, Malnutrition
Clinical Trial of Alanyl-Glutamine or Glycine in Children With Persistent Diarrhea or Malnutrition
This is a double blinded randomized clinical trial of Alanyl-Glutamine or Glycine in children with persistent diarrhea or malnutrition.
- Trial name
- NCT00338221
- Testing
- alanyl-glutamine, glycine
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Diarrhea, Malnutrition, Other Nutritional Deficiencies
HIAS II - Study of Nutritional Supplementation in Hospitalized Children With Persistent Diarrhea or Malnutrition
This study will determine the effect of 7 days supplementation of alanyl-glutatime or glycine on the damaged intestinal barrier function on day 8 in children with persistent diarrhea or malnutrition.
- Trial name
- NCT00133562
- Testing
- Alanyl-glutamine, Glycine
- Volunteers
- 108 people
- Sponsor
- University of Virginia
Metabolic Syndrome
Impact of Exercise Training Intensity on Abdominal Visceral Fat and Risk Factors Associated With the Metabolic Syndrome
The purpose of this study is to determine if sixteen weeks of high intensity physical training is more effective than sixteen weeks of low intensity physical training in reducing abdominal fat and lowering risk factors associated…
- Trial name
- NCT00350064
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Corneal Transplantation
A Prospective Study of the Effect of Topical Sodium Hyaluronate Immediately Post-PKP on Time to Reepithelialization
Hypothesis: 1% sodium hyaluronate (Healon), applied at end of surgery to the surface of a corneal transplant will not shorten graft reepithelialization time when compared to coating with nothing.
- Trial name
- NCT00570648
- Testing
- sodium hyaluronate
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Kidney
Assessment of Changes in Renal Cortical and Medullary Blood Flow by Contrast Ultrasound
The purpose of this study is to determine if contrast enhanced ultrasound (CEU) using microbubbles, is useful in assessing changes in kidney blood flow.
- Trial name
- NCT00631553
- Testing
- perflutren lipid microspheres
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections
Continuous Exhaled Breath Condensate pH in Mechanically Ventilated Patients
Given the possible prognostic relationship between exhaled breath condensate pH and clinical symptoms, it is quite plausible that exhaled breath condensate pH can prove useful in the intensive care unit.
- Conditions
- Respiratory Distress Syndrome, Adult, Respiratory Syncytial Virus Infections, Pneumonia, Acute Lung Injury
- Trial name
- NCT00429637
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Virginia
Diabetes Mellitus, Type 2, Obesity
Lifestyle Intervention's Impact on Health Care Costs
The ICAN Pilot project aims to evaluate the differences in economic, clinical and quality of life outcomes of a nutrition intervention involving lifestyle case management and medical nutrition therapy by a registered dietitian…
- Trial name
- ICAN (NCT00717158)
- Testing
- Usual medical care, Lifestyle Case management
- Where
- United States
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Osteoarthritis, Knee
Effects of Electrical Stimulation on Osteoarthritis of the Knee
The purpose of this study is to find out whether electrical stimulation can reduce knee pain and increase function in people with osteoarthritis of the knee.
- Trial name
- NCT00601497
- Testing
- InterX 5000
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- University of Virginia
Lymphoma
Bortezomib and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways.
- Trial name
- NCT00265928
- Testing
- bortezomib, rituximab, antibody therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of Virginia
Postoperative Ileus
Effects of Intravenous Local Anesthetic on Bowel Function After Colectomy
Epidural local anesthetics are the gold standard for shortening duration of bowel dysfunction after bowel surgery. Previous studies suggest that their effect may be in part a result of actions of the local anesthetic outside the…
- Trial name
- NCT00600158
- Testing
- bupivacaine with hydromorphone, lidocaine
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Virginia
Aging
Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults
The purpose of this study is to determine whether treatment of healthy older men and women with oral MK-677 for 12 months will enhance pulsatile GH release and increase mean GH and IGF-I concentrations into the range of young…
- Trial name
- MOT089 (NCT00474279)
- Testing
- Orally active growth hormone secretagogue (MK-677)
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Type 2 Diabetes
Lifestyle Interventions for Long Term Diabetes Control
Lifestyle interventions have been shown to reduce heart disease risk and improve blood sugar control in clinical trials. This project will investigate whether those lifestyle interventions can be implemented long-term, in usual…
- Trial name
- NCT00364312
- Testing
- diet and physical activity
- Where
- United States
- Volunteers
- 390 people, healthy volunteers welcome
- Sponsor
- University of Virginia