Clinical trials: sponsored by University of Washington
Insomnia, Alcohol Use
Brief Interventions to Reduce Comorbid Alcohol and Cannabis Misuse and Sleep Impairment in Young Adults (Rest-Up RCT)
This study is designed to evaluate an integrated intervention to reduce alcohol and marijuana use and consequences and improve sleep among young adults with comorbid heavy episodic drinking, marijuana use, and sleep impairment.
- Conditions
- Insomnia, Alcohol Use, Marijuana Use
- Trial name
- NCT06736444
- Testing
- Brief Behavioral Therapy for Insomnia (BBTI), Brief Alcohol Screening and Intervention for College Students (BASICS), Attention Control
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- University of Washington
Child Abuse, Child Neglect
Families Together: Intervention for Reunified Families
Birth parents of young children who have been placed into foster care are a highly vulnerable population of caregivers. Little is known about the ability of existing prevention programs to intervene with birth parents who have…
- Trial name
- NCT04382677
- Testing
- Promoting First Relationships ®, Resource & Referral
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- University of Washington
Stroke, Ischemic
Motor Recovery Through Plasticity-Inducing Cortical Stimulation
Using the CorTec Brain Interchange (BIC) System, we will examine the effect of a plasticity-inducing therapy regime on the rehabilitation of upper limb impairment post-stroke.
- Trial name
- MRPICS (NCT06506279)
- Testing
- CorTec Brain Interchange (BIC) System
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Washington
STI
Weekly Doxycycline DOT for STI Prevention Among Cisgender Women Taking HIV PrEP in Kisumu, Kenya
The first study of doxycycline postexposure prophylaxis for cisgender women did not reduce incident STIs likely due to low use of doxycycline.
- Trial name
- NCT06582966
- Testing
- Doxycycline
- Where
- Kenya
- Volunteers
- 60 people
- Sponsor
- University of Washington
Chronic Pain
Digital Therapeutic for Chronic Pain Feasibility Study
The investigators will conduct a 2-arm randomized control feasibility study to evaluate: 1) the feasibility of using the mobile app and an optional activity tracker, 2) the feasibility of conducting a 2-arm trial, and 3) estimate…
- Trial name
- NCT06000007
- Testing
- 2Morrow Chronic Pain Self-Management Program - digital therapeutic mobile app, Treatment as usual
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- University of Washington
Cystic Fibrosis, Colorectal Cancer
Colorectal Cancer Screening in Cystic Fibrosis
This multi-center study will compare multi-target DNA and quantitative FIT stool-based testing to colonoscopy in individuals with Cystic Fibrosis (CF) undergoing colon cancer screening with colonoscopy.
- Conditions
- Cystic Fibrosis, Colorectal Cancer, Adenoma
- Trial name
- NICE-CF (NCT05362344)
- Testing
- Stool tests
- Where
- 26 sites in United States
- Volunteers
- 350 people
- Sponsor
- University of Washington, the Collaborative Health Studies Coordinating Center
Suicidal Ideation and Behavior
Suicide Treatment and Recovery in Integrated Behavioral Health (STRIBH)
The suicide rate has increased 28% over the past two decades while heart disease, diabetes, and cancer mortality has declined. Starting in 2011, new standards have led to improved adoption and reach of suicide risk surveillance…
- Trial name
- STRIBH (NCT06700993)
- Testing
- Treatment as Usual in Collaborative Care or Integrated Behavioral Health, Connections model
- Sponsor
- University of Washington
Retinoblastoma Bilateral, Retinoblastoma Unilateral
Detailed Phenotypic and Genotype Study to Correlate RB1 Mutations Relating to Primary Ocular Tumors and Secondary Extra-ocular Metastasis.
The goal of this observational study is undertake a detailed phenotypic and genotypic study of patients with ocular and secondary cancers due to mutations in the RB1 gene.
- Conditions
- Retinoblastoma Bilateral, Retinoblastoma Unilateral, Retinoblastoma, Extraocular, Retinoblastoma, Recurrent
- Trial name
- NCT06725173
- Testing
- Targeted Long-read sequencing
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Multiple Sclerosis
Factorial Optimization Trial to Test Cognitive Behavioral Therapy Components for Multiple Sclerosis Fatigue
This randomized controlled factorial trial will examine whether and how relaxation training, behavioral activation, and cognitive therapy improve fatigue and functioning in fatigued adults living with multiple sclerosis.
- Trial name
- NCT06809192
- Testing
- 4-session Relaxation Training, 4-session Behavioral Activation, 4-session Cognitive Therapy
- Where
- United States
- Volunteers
- 112 people
- Sponsor
- University of Washington
HIV, Heart Failure
Proof-of-concept of a Behavioral Intervention to Improve the Cardiovascular Health of People Living With HIV
Heart failure (HF) is a growing health and economic burden around the globe, and it remains a leading cause of morbidity and mortality among the general population.
- Trial name
- HEICA-HIV-2025 (NCT07105007)
- Testing
- Exercise Intervention, Tailored Education sessions, Behavioral coaching
- Where
- 2 sites in United States, Brazil
- Volunteers
- 30 people
- Sponsor
- University of Washington
Parenting, Parent-Child Relations
Delivering Evidence-Based Parenting Services to Families in Child Welfare Using Telehealth
The goal of this randomized controlled trial is to compare Promoting First Relationships - Home Visit (PFR-HV) to Promoting First Relationships - Telehealth (PFR-T) among parents of 6-12 month olds in the child welfare system.
- Conditions
- Parenting, Parent-Child Relations, Child Behavior, Child Maltreatment
- Trial name
- NCT06109766
- Testing
- Promoting First Relationships
- Where
- United States
- Volunteers
- 357 people, healthy volunteers welcome
- Sponsor
- University of Washington
Cirrhosis, Chronic Liver Disease
Copper Supplementation in Cirrhosis
End stage liver disease or cirrhosis is a major cause of mortality in the United States and the world. Other than targeting the underlying cause, such as alcohol cessation and antiviral therapy, very few medical treatments can…
- Conditions
- Cirrhosis, Chronic Liver Disease, Fibrosis, Infection
- Trial name
- NCT07471542
- Testing
- Copper Gluconate
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Washington
Overweight/Obesity, Puberty
Improving Health Among Disadvantaged Girls to Slow Pubertal Onset and Reduce Long-term Health Risks
This study is testing whether improving health in girls during the prepubertal period may slow the onset of puberty. This study will focus on prepubertal girls who have a high weight status (at or above the 85th percentile for…
- Conditions
- Overweight/Obesity, Puberty, Health Behavior, Cardiometabolic Health
- Trial name
- NCT07460544
- Testing
- Family-Based Treatment (FBT)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of Washington
Neurodevelpmental Delays, Neurodevelopment
Implementation Outcomes and Cost-effectiveness of Developmental Monitoring for Children Exposed to HIV
The goal of this study is to learn about how to best carry out neurodevelopmental screening methods (tests to see if a young child can use support with brain development) in routine clinic visits in Botswana and Kenya among…
- Conditions
- Neurodevelpmental Delays, Neurodevelopment, Neurodevelopment Outcome
- Trial name
- IMPLEMENT (NCT07457411)
- Testing
- Neurodevelopmental screening
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- University of Washington
Alcohol Use, Unspecified
Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of High School
The purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes…
- Trial name
- NCT06191861
- Testing
- Most hoped for future self, Most feared future self, Control (trip to zoo)
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Washington
Schizophrenia, Bipolar Disorder
Technology-Assisted Implementation of a Mobile Health Program for Serious Mental Illness
The goal of this clinical trial is to learn about how a digital training platform can enhance implementation and effectiveness of a validated mHealth system, called FOCUS, in people with serious mental illness.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder, Schizo Affective Disorder
- Trial name
- NCT05725785
- Testing
- FOCUS participants
- Where
- 3 sites in United States
- Volunteers
- 191 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neurodevelopment, Child Growth
Building Opportunities for Nurturing Care to Enhance Child Development in Eastern and Southern Africa
The goal of this randomized controlled trial is to adapt and test a package of interventions to provide nurturing care for children aged 0-2 years in three countries (Botswana, Kenya, Zimbabwe).
- Trial name
- BONDS (NCT07430826)
- Testing
- Friendship Bench, Infant and Young Child Feeding (IYCF) Curriculum, Play-Based Curriculum
- Volunteers
- 1,260 people, healthy volunteers welcome
- Sponsor
- University of Washington
Chronic Pain
Matching Adults to Treatments for Chronic Pain (MATCH) Study
Chronic pain is a prevalent, disabling problem affecting as many as 50% of men and 75% of women Veterans. Cognitive Behavioral Therapy (CBT) is the current gold standard treatment for chronic pain.
- Trial name
- MATCH (NCT05699252)
- Testing
- Cognitive Behavioral Therapy (CBT), Hypnotic Cognitive Therapy (HYP-CT), Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- 3 sites in United States
- Volunteers
- 331 people
- Sponsor
- University of Washington
Alcohol Use, Unspecified
Narrative Writing to Promote Healthy Decisions About Alcohol During the Transition Out of College
The purpose of the proposed research is to evaluate (1) whether a future possible self task (FPST) can lead to changes drinking identity (DI; how much one associates one's self with drinking) and (2) whether the FPST and changes…
- Trial name
- NCT07418424
- Testing
- Most hoped for future self, Most feared future self, Balanced future self
- Where
- United States
- Volunteers
- 468 people, healthy volunteers welcome
- Sponsor
- University of Washington
Neoplastic Syndromes, Hereditary
Applying Population Management Best Practices to Preventative Genomic Medicine Trial
Preventive genomic medicine, particularly identification of individuals with inherited cancer risk, can improve longevity and quality of life, yet adherence to risk management following cancer genomic testing is poor.
- Trial name
- CARE-HCS (NCT07053813)
- Testing
- Web resources, Personalized outreach
- Where
- 2 sites in United States
- Volunteers
- 900 people
- Sponsor
- University of Washington
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